Wang Yixiao, Wang Nan, Yang Jun, Lim Xue Yee, Wu Xingyi, Zhang Tong, Li Ling
DOI:10.16305/j.1007-1334.2025.z20250903005
摘要:Glycyrrhizae Radix et Rhizoma (Gancao) is the dried roots and rhizomes of Glycyrrhiza uralensis Fisch, Glycyrrhiza inflata Bat, or Glycyrrhiza glabra L. It possesses the efficacy of tonifying the spleen, reinforcing Qi, moistening the lungs to relieve cough, clearing heat and detoxifying, as well as harmonizing the properties of other medicinal herbs. With a long history of application, it serves as an important herb for replenishing deficiency and detoxification. In recent years, researchers have conducted extensive studies on the chemical constituents, pharmacological actions, and clinical applications of glycyrrhiza. These studies have confirmed that its chemical profile primarily comprises triterpenoid saponins, flavonoids, polysaccharides, coumarins, along with various amino acids and volatile oils. Pharmacological studies have demonstrated that glycyrrhiza possesses antitumor, antiviral, anti-inflammatory, and neuroprotective effects, etc. Clinical research has indicated its applicability in treating a range of conditions, including respiratory, gastrointestinal, and skin disorders. This paper reviews relevant literature on glycyrrhiza from recent years and provides a systematic summary of its chemical constituents, pharmacological actions, and clinical applications, aiming to facilitate further basic research and industrial development of this herb.
关键词:Glycyrrhizae Radix et Rhizoma;pharmacological action;clinical applications;chemical constituents;Chinese materia medica;review
Zhou Xinru, Li Huizhen, Liu Yun, Ding Yue, Lu Lu, Zhang Tong
DOI:10.16305/j.1007-1334.2026.z20251126004
摘要:Angelica Sinensis Radix, known as "the holy medicine for blood disorders", has a long history of medicinal use and is often referred to as "present in nine out of ten classical formulas". It acts as either the monarch medicine or the minister medicine in more than ten classical formulas. And its chemical components mainly include volatile oils, flavonoids, organic acids, polysaccharides and amino acids. Based on these components, Angelica Sinensis Radix has a variety of pharmacological effects, such as promoting hematopoietic function, anti-inflammatory, anti-tumor, regulating immunity, and protecting liver. In terms of quality research, the cultivation place of origin, processing methods and post-harvest processing methods will all affect the quality and efficacy of Angelica Sinensis Radix. A systematic review of the chemical components, pharmacological effects and quality control of Angelica Sinensis Radix is conducted in order to provide reference for the development and application of Angelica Sinensis Radix and its compound preparations.