This paper introduces Professor Lu Chuanjian's clinical experience in treating chronic urticaria through the spleen and kidney. Chronic urticaria， characterized by its symptom clusters （a group of pruritic wheals）， is pathologically categorized under "water dampness". The onset and recurrence of urticaria are closely linked to the "inefficient transformation of water dampness"， fundamentally attributed to "spleen and kidney yang deficiency". The core pathogenesis is identified as "spleen and kidney yang deficiency at its root， with dampness and wind intermingling as its manifestation". The treatment emphasizes "warming the kidney and strengthening the spleen to treat the root， and expelling wind and transforming dampness to target the symptoms". Professor Lu formulates the core formula "Guben Kangmin Fang" （Root-Solidifying and Anti-Allergy Formula） for syndrome differentiation-based treatment. The therapeutic efficacy has proven to be significant. One proven case is provided for illustration.