最新刊期
期 8 ， 2019
- 关键词：Crohn’s disease;irritable bowel syndrome;strengthening spleen and nourishing yin;experience of famous doctor;Yu Jianer
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发布时间：2022-08-31 - 摘要：This paper discusses Xie Jingri’s experience in the treatment of diabetic gastroparesis. Professor Xie puts forward two points of his own opinion on treating diabetic gastroparesis: pathogenesis view of liver -spleen depression and etiology view of essence-turbid blending of phlegm-lipit-blood stasis. Professor Xie promotes the combination of traditional Chinese and Western medicine to treat the disease. First, he identifies the direction of the treatment by differentiating the cause of the disease, and then formulates therapeutic rules by differentiating syndrome. Professor Xie’s experience of treating diabetic gastroparesis can be sumed up by the following three points:“the combination of regulating and strengthening”,“the thought of dredging intestines and descending adverse flow of qi” and “the combination of strengthening and eliminating”. And one proven case is presented.关键词：diabetes mellitus;gastroparesis;TCM therapy;experience of famous doctor;Xie Jingri
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发布时间：2022-08-31 - 摘要：This paper introduces Professor Deng Yueyi’s experience in the treatment of kidney disease from the liver. It is believed that kidney disease is related not only with the lungs, spleen and kidneys, but also with the liver, for the failure of liver to convey and disperse is an important factor in the pathogenesis of kidney disease. Clinically, the kidney disease can be treated from the liver, with clearing liver, calming liver and soothing liver as the basic methods. For liver dampness, the method of clearing liver is used; for yin deficiency and yang hyperactivity, the methods of calming liver and softening liver are applied; for liver depression and qi stagnation, the methods of soothing liver and regulating qi are used. The method of soothing liver should be used throughout the treatment. And three proven cases are presented.关键词：kidney disease;treatment of kidney disease from the liver;clinical experience;Deng Yueyi
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发布时间：2022-08-31 - 摘要：This article summarizes the clinical experience of Professor Cheng Yan in the treatment of herpetic pharyngitis. Professor Cheng holds that the clinical manifestations are mainly caused by exogenous wind and heat,toxin in the lung and stomach and consumption of yin due to residual heat. She treats the disease by the methods of dispelling wind and eliminating pathogenic factors,clearing away heat and detoxifying,invigorating qi and nourishing yin, and pays attention to the method of giving the pathogenic factors a way out. In treating the disease, She is very careful about prescribing the bitter and cold herbs and good at applying the herb of Baimaogen (Rhizome Imeratae), modifying the prescription in accordance with the symptom and solar terms of four seasons. And one proven case is presented.关键词：herpetic pharyngitis;throat obstruction;man integrated with nature;experience of famous doctors;Cheng Yan
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发布时间：2022-08-31 - 摘要：This paper explores the position and function of the thought of “preserving liquid” in the treatment of acute leukemia. It is considered that acute leukemia is characterized by exuberant heat toxin, yin deficiency and blood heat, which belongs to febrile disease, acute phthisis and so on. In the treatment of the disease, attention should be paid to nourishing yin and saving liquid (Jin). One proven cases are presented.关键词：acute leukemia;heat toxin;preserving liquid
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发布时间：2022-08-31 - 摘要：This paper explores the clinical experience of Professor Wu Shentao in the treatment of painful diabetic peripheral neuropathy(limb pain of diabetes). The four ideas of “Bo(extensiveness), Jing(precision), Qi(singularity) and Shen(caution)” have been summarized in his treatment of the disease based on following five syndromes: blood deficiency and cold stagnation, turbid phlegm obstructing meridian, retention of turbidity and toxicity and collateral stasis, qi deficiency and blood stasis, and deficiency of both qi and yin and overstrain of governor vessel. And one proven case is presented.
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发布时间：2022-08-31 - 关键词：Jiang Chunhua;scholarship;book;integrated Chinese and Western medicine;modern experiment of TCM
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发布时间：2022-08-31 - 摘要：Based on ancient and modern literatures of TCM and clinical observation, this paper offers a concept of “taking dryness and dampness as the principle” and detailedly illuminates the specific application in the treatment of chronic cough from the aspect of argument, ways of syndrome differentiation (such as identifying between dryness and dampness, identifying between deficiency and excess, identifying among pathogenic factors, and determining location of disease), and selecting prescriptions and using medicines. It may provide beneficial ways and reference for the treatment of chronic cough with Chinese medicine.关键词：chronic cough;dry cough;wet cough;ways of differentiation of symptoms and signs;TCM therapy
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发布时间：2022-08-31 - 摘要：Objective:To systematically evaluate the effectiveness and safety of rotary drawing manipulation in the treatment of frozen shoulder. MethodsLiteratures about clinical randomized controlled trials (RCTs) on rotary drawing manipulation for frozen shoulder were electronically searched from Pubmed, Cochrane library, Embase, CBM, CNKI, VIP, WANGFANG and other databases at home and abroad from 2007 to 2017, and final literatures were manually selected based on inclusion and exclusion criteria to extract valid data. Quality evaluation was performed on the included studies by the Cochrane systematic evaluation method, and meta-analysis was conducted on data using the RevMan 5.3 software. Results:①Ten RCT literatures involving 1084 patients with frozen shoulder were included. ②Most of the 10 studies included did not describe or were not clear about the criteria of assignment masking, blinding, being lost to follow-up or withdrawal, and the overall quality of literatures was low. ③Meta-analysis showed that the treatment group (rotary drawing manipulation therapy) was superior to the control group (other non-drug therapy) in increasing the total effective rate [RR=1.19,5% CI (1.10,1.29), P＜0.000 1], the curative rate [RR=1.42,5% CI (1.05,1.92), P=0.02] and improving the VAS score [manipulation vs acupuncture and moxibustion:WMD=-0.73,5% CI (-1.08, -0.39), P＜0.000 1; manipulation vs block:WMD=-1.50,5% CI (-1.88, -1.12); Z=7.79, P＜0.000 01]. Conclusion:Rotary drawing manipulation therapy improves the symptoms of frozen shoulder, with efficacy superior to the other non-drug therapies. However, more multi-center randomized controlled trials with a larger sample size are needed to further confirm the conclusion due to the poor quality of methodology for including the literatures and the differences among the studies included.关键词：manipulation therapy;massage;frozen shoulder;systematic evaluation;Meta-analysis
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发布时间：2022-08-31 - 摘要：This paper aims at comparing the different classification systems of liver diseases between current national standards and the ICD-11 TM chapter. By analyzing the location and physiological characteristics of the liver system, the basic classification attributes involved in liver diseases are classified according to the degree of association. Cluster analysis is carried out by SPSS 20.0 to explore the rules and approaches of constructing the disease classification system in traditional Chinese medicine. It is believed that in establishment of TCM disease classification system, multi-attribute and multi-dimension integration may be attempted by combining theories with quantitative indicators.关键词：liver system diseases;disease classification in TCM;traditional medicine;ICD-11
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发布时间：2022-08-31 - 关键词：Dachaihu Decoction;physique;hyperuricemia
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发布时间：2022-08-31 - 摘要：Through the analysis of the representative medical cases, this paper probes into the clinical thought and characteristics of Liu Baoyi’s Medical records. Banxia Xiexin decoction and Xuanfu Daizhe decoction have the function of regulating Zhongjiao(middle energizer), replenishing and reducing simultaneously; Xiaoqinglong decoction and Lingguizhugan decoction having the warming and resolving function, is good for treating retention of fluid and Dachengqi decoction for emergency.关键词：Liu Baoyi’s Medical Records;classical prescription;Zhang Zhongjing
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发布时间：2022-08-31 - 摘要：Through literature review, this paper summarizes the understanding of hemorrhoids of the three major academic schools in the Ming and Qing dynasties (Zhengzong sect, Xinde sect and Quansheng sect). The etiology of hemorrhoids mainly includes four aspects: improper diet, abnormal change of emotions, sedentary weight bearing and excess of sexual intercourse. Chen Shigong (Zhengzong sect) attached great importance to the use of external treatment, advocating early diagnosis and treatment. Gao Bingjun (Xinde sect) paid great attention to internal therapy and did well in judging the prognosis by combining pulse diagnosis while protecting the healthy qi. Wang Weide (Quansheng sect) advocated the identification of cause according to syndrome differentiation, emphasizing that the protection of anus should be considered during the use of hemorrhoid-withering drugs.关键词：hemorrhoids;Ming dynasty;Qing dynasty;academic schools;Surgical authentic;Experience Gained in Treating External Sores;Collections of Treatment Therapy for Extermal Disorders
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发布时间：2022-08-31 - 摘要：Objective:To observe the efficacy and safety of Tongluo Shenggu (TLSG) Capsule in the treatment of osteonecrosis of the femoral head (ONFH) with syndrome of stagnation of sinews and vessels. MethodsIn a multi-center, randomized, double-blind, double-dummy, positive-controlled clinical study, 600 patients with ONFH were randomly assigned into trial group and control group at a ratio of 2∶1. The control group was treated with Tongluo Shenggu Capsule simulant and Jianggusheng Pill, while the trial group was treated with Tongluo Shenggu Capsule and Jianggusheng Pill simulant. The treatment course was 12 weeks. The changes in Harris score, TCM syndrome score and ARCO staging of ONFH were compared at different time points (before treatment, at 4,8 and 12 weeks of treatment and at 4 weeks after drug withdrawal) and safety was evaluated. Results:①=1\*GB3At 4,8 and 12 weeks of treatment and 4 weeks after drug withdrawal, there was significant difference in Harris score from baseline in both groups (P<0.05). The Harris score was higher in the trial group than in the control group (P<0.05) at 12 weeks of treatment and 4 weeks after drug withdrawal; and there was significant difference from baseline between the groups at 8 and 12 weeks of treatment and 4 weeks after drug withdrawal (P<0.05). ②=2\*GB3At 4,8 and 12 weeks of treatment and 4 weeks after drug withdrawal, the scores of TCM syndrome decreased significantly in both groups compared to baseline before treatment (P<0.05). There was no significant difference from baseline in TCM syndrome scores between the groups at 4,8 and 12 weeks of treatment and 4 weeks after drug withdrawal (P>0.05). ③=3\*GB3There was no significant difference in ARCO staging between the groups at 12 weeks of treatment (P>0.05). ④=4\*GB3There was no significant difference in safety evaluation between the groups (P>0.05). Conclusion:TLSG Capsule shows satisfactory efficacy in treating ONFH (syndrome of stagnation of sinews and vessels), and compared with Jiangusheng Pill, it better improves the hip function of patients, and is safe and reliable.关键词：Tongluo Shenggu Capsule;osteonecrosis of the femoral head;multi-center;randomized control;double-blind
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of Lishi Jiedu Formula (LSJD) for oral administration and Tongfu Zhuyu Formula (TFZY) for enema combined with conventional therapy in treating hepatitis B virus (HBV) associated acute-on-chronic liver failure (HBV-ACLF). Methods139 patients with HBV-ACLF were randomly assigned into treatment group (72 patients) and control group (67 patients). The control group was treated with comprehensive medical treatment, while the treatment group was treated with LSJD and TFZY on the basis of the treatment measures of the control group. The two groups were treated for 8 weeks. Survival rate was observed, and liver function [alanine aminotransferase (ALT), total bilirubin (TBil) and cholinesterase (CHE)], prothrombin activity (PTA), hepatitis B virus-DNA (HBV-DNA), and score of model for end-stage liver disease (MELD) were compared at 2,4 and 8 weeks of treatment and 12 weeks after treatment. Results:①The total survival rate and the 2- and 4-week survival rates were 65.3%, 86.1% and 95.2% respectively in the treatment group, and 43.3%, 67.2% and 80.0% respectively in the control group, with significant difference between the two groups (P<0.05). ②There were significant differences in the levels of serum ALT, TBil, CHE and PTA and MELD scores in the groups at 2,4 and 8 weeks of treatment and at 12 weeks after treatment compared to those before treatment (P<0.05); there were significant differences in the levels of serum ALT, TBil, CHE and PTA and MELD scores between the two groups at 4 and 8 weeks of treatment (P<0.05). ③The level of HBV-DNA decreased in both groups at 2,4 and 8 weeks of treatment and at 12 weeks after treatment compared to that before treatment (P<0.05); the level was lower in the treatment group than in the control group at 8 weeks of treatment (P<0.05). Conclusion:LSJD for oral administration and TFZY for enema combined with conventional therapy shows satisfactory effect in treating HBV-ACLF. Compared with conventional therapy, it improves the liver function and coagulation function, reduces the level of HBV-DNA, and improves the short-term survival rate of patients with HBV-ACLF.
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of Zishen Qingqi Granule combined with conventional therapy in the treatment of mildly to moderately active systemic lupus erythematosus (SLE) and effect of the drug on dosage of hormone therapy. MethodsSixty-four patients with SLE who met the inclusion criteria were randomly assigned into treatment group and control group, 32 patients in each group. The basic therapy was prednisone combined with hydroxychloroquine sulfate in both groups and in addition, the treatment group was given Zishen Qingqi Granule and the control group received placebo. The treatment course was 3 months in both groups. Changes in SLEDAI score, TCM syndrome score, dosage of hormone and relevant laboratory indicators (erythrocyte sedimentation rate, Complement C3 and C4, anti-ds-DNA antibody, alkaline phosphatase, serum calcium and phosphorus and osteocalcin) were observed. Results:After treatment, the SLEDAI score, TCM syndrome score and dosage of glucocorticoids were significantly reduced in both groups (P＜0.05); they were significantly lower in the treatment group than in the control group (P＜0.05). After treatment, the ds-DNA level decreased in both groups (P＜0.05), and the other laboratory indicators had no statistically significant differences (P＞0.05). There were no significant differences in laboratory indicators between the groups after treatment (P＞0.05). Conclusion:Zishen Qingqi Granule is effective in the treatment of SLE. It significantly improves TCM syndrome and helps to withdraw and reduce the dose of hormone.关键词：systemic lupus erythematosus;Zishen Qingqi Granule;glucocorticoid;clinical observation
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发布时间：2022-08-31 - 摘要：Objective:To investigate the effect of extracorporeal shock wave acupoint therapy on shoulder pain and the levels of serum 5-hydroxytryptamine (5-HT) and prostaglandin E2 (PGE2) in patients with shoulder periarthritis. Methods82 patients with shoulder periarthritis were randomly assigned into treatment group and control group, 41 patients in each group. The control group was treated with routine extracorporeal shock wave therapy, while the treatment group was treated with extracorporeal shock wave acupoint therapy. The treatment course was 4 weeks. The therapeutic effect was observed. Changes in VAS score of shoulder pain, shoulder range of motion as well as levels of serum 5-HT and PGE2 were compared. Results:①There was no drop-out during the trial. ②The total effective rate was significantly higher in the treatment group (97.56%) than in the control group (80.49%) (P<0.05). ③After treatment, the VAS scores of shoulder pain decreased in both groups (P<0.05); and the difference in the scores before and after treatment were greater in the treatment group than in the control group (P<0.05). ④After treatment, the shoulder range of motion increased significantly in both groups (P<0.05); and the difference in shoulder range of motion before and after treatment was greater in the treatment group than in the control group (P<0.05). ⑤After treatment, the levels of serum 5-HT and PGE2 decreased significantly in both groups (P<0.05); and the differences in the levels before and after treatment were greater in the treatment group than in the control group (P<0.05). Conclusion:Extracorporeal shock wave acupoint therapy is effective in patients with shoulder periarthritis as it relieves shoulder pain, increases shoulder range of motion and reduces the levels of PGE2 and 5-HT in serum.关键词：shoulder periarthritis;extracorporeal shock wave;acupoint therapy;shoulder range of motion;5-hydroxytryptamine;prostaglandin E;2
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发布时间：2022-08-31 - 摘要：Objective:To explore the changes in tongue color, blood flow of tongue microcirculation and ICAM-1 in rats with type 2 diabetes mellitus. MethodsExcept for the 10 rats in the normal group, the other Wistar rats were used to establish the model of type 2 diabetes mellitus. Rats for successful modelling were randomly assigned into model group and inhibitor group, 10 rats in each group. In the inhibitor group, PDTC, the inhibitor of the NF-κB signaling pathway was intraperitoneally injected for 8 weeks. The tongue images of diabetic rats were collected and analyzed using “small TDA-1 tongue imager” and “tongue digital analysis system (TDAS)”. The changes of hemodynamics in tongue microcirculation of diabetic rats were observed by laser Doppler flowmetry. The concentrations of ICAM-1 in serum, tongue tissue and liver tissue were observed by ELISA. Results:In comparison of objective indicators of tongue images, it was shown that compared with the normal group, zhiClrI and taiClrI (the quantitative indicators of tongue color) were significantly reduced, while zhiClrS and taiClrS (the quantitative indicators of tongue color) were significantly increased in the model group and the inhibitor group (P<0.05). Compared with the model group, zhiClrS (the quantitative indicator of tongue color) was reduced in the inhibitor group (P<0.05). In comparison of local hemodynamics of the tongue, it was shown that compared with the normal group, mean perfusion area of blood flow in local tongue microcirculation decreased significantly in the normal group and the inhibitor group (P<0.05). In comparison of adhesion factor, it was shown that compared with the normal group, the concentration of serum adhesion factor ICAM-1 increased (P<0.05) and the concentration of ICAM-1 in tongue tissue and liver tissue was significantly increased (P<0.01) in the model group. Compared with the model group, the concentration of ICAM-1 in tongue tissue and liver tissue was significantly reduced in the inhibitor group (P<0.01). Conclusion:The changes of tongue color in rats with type 2 diabetes mellitus may be related to disorder of local microcirculation of the tongue and increase of the adhesion factor ICAM-1.关键词：type 2 diabetes mellitus;objectification of tongue image;disorder of microcirculation;ICAM-1;rats
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发布时间：2022-08-31 - 摘要：Objective:To investigate the effect of Liuwei Dihuang Pill on glucose metabolism in insulin-resistant mice and its relationship with osteocalcin. MethodsMice with insulin resistance induced by high-fat diet were divided into low-, middle- and high-dose groups of Liuwei Dihuang Pill, Western medicine group (pioglitazone), model group and normal group. After 8 weeks of intervention, fasting blood glucose (FBG), fasting insulin (Fins) and osteocalcin were detected. Results:Compared with the model group, FBG was improved significantly in insulin-resistant mice in the low-dose group (P<0.01); Fins was significantly lower in the low- and high-dose groups of Liuwei Dihuang Pill (P<0.01, P<0.05); uncarboxylated osteocalcin was increased significantly in insulin-resistant mice in the groups of Liuwei Dihuang Pill (P<0.01, P<0.05) and the ratio of uncarboxylated to carboxylated osteocalcin increased significantly in the low-dose group of Liuwei Dihuang Pill. Correlation analysis showed a negative correlation between uncarboxylated osteocalcin and FBG (P<0.05); the ratio of uncarboxylated to carboxylated osteocalcin was negatively correlated with FBG (P<0.01) and Fins (P<0.05). Conclusion:FBG and Fins are significantly improved in insulin-resistant mice in the low-dose group of Liuwei Dihuang Pill. Compared with uncarboxylated osteocalcin, the ratio of uncarboxylated to carboxylated osteocalcin better explains the improvement of glucose metabolism by Liuwei Dihuang Pill.关键词：Liuwei Dihuang Pill;insulin resistance;osteocalcin;glucose metabolism;mice
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发布时间：2022-08-31 - 摘要：Objective:To observe and evaluate the effect of Supplemented Taohong Siwu Decoction (THSW) on retinal vein occlusion (RVO) in rats by establishing the model of RVO in SD rats by using Rose Bengale combined with laser photodynamics and THSW was given by gavage. Methods① The model of RVO in SD rats was established by using Rose Bengale combined with laser photodynamics. ②THSW at high, medium and low concentrations was given by gavage for 3 weeks and the fundus was observed at regular intervals. Results:The model of RVO in SD rats was successfully established, as shown by FFA and the light and electron microscopy. In the fundus, it was found out that the improvement of fundus lesions with THSW was superior to the natural course of the model, with most significant effect in the high concentration group. Conclusion:Supplemented Taohong Siwu Decoction given by gavage reduces fundus lesions including retinal hemorrhage and edema in rat model of RVO.关键词：retinal vein occlusion;Supplemented Taohong Siwu Decoction;rats
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发布时间：2022-08-31 - 摘要：Objective:To determine the content of total mercury in Zizhu Ointment, and to provide evidence for its effectiveness and safety. MethodsAfter microwave digestion of samples, the content of total mercury was determined by inductively coupled plasma optic emission spectrometry (ICP-OES). Results:In the established method for determining total mercury, the linearity was Y=4 587X-150.1 and the correlation coefficient was 0.999 9. The recovery rate was 89.29%~101.36% and the average content of total mercury in Zizhu Ointment was 3.20%, with RSD of 1.28%. Conclusion:ICP-OES is a rapid, accurate and reliable method for the determination of total mercury in Zizhu Ointment.关键词：Zizhu Ointment;total mercury;ICP-OES
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发布时间：2022-08-31 - 摘要：Considering relevant studies on reversal of multidrug resistance in liver cancer in recent 10 years both at home and abroad, this paper summarizes the reversal effect of traditional Chinese medicine in liver cancer in inhibiting membrane transporter, inhibiting multidrug resistance (MDR) genes, inhibiting the anti-apoptotic pathway, reversing enzyme-mediated MDR and improving the microenvironment of tumor cells, and also summarizes the existing problems in and the direction of research, so as to provide new ideas for clinical treatment.关键词：traditional Chinese medicine;liver cancer;multidrug resistance;reversal;mechanism;review
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发布时间：2022-08-31 - 摘要：This paper reviews the research progress on the mechanism of action of TCM in Th17/Treg imbalance in asthma. Th17/Treg imbalance plays an important role in the pathogenesis of asthma. It has been shown that in traditional Chinese medicine, herbal monomers (baicalin, icariin, etc.), a variety of compounds (Guben Fangxiao Decoction, Pingchuan Formula, etc.) and external treatment (acupuncture and moxibustion) can reduce airway inflammation and improve asthma symptoms by regulating the number of Th17/Treg cells and the relevant inflammatory cytokines.关键词：bronchial asthma;Th17;Treg;traditional Chinese medicine;review
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发布时间：2022-08-31
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