最新刊期
期 3 ， 2016
- 摘要：This paper introduces Cai Xiaosun’s experience of treating endometriosis with associated prescriptions according to different periods and removing blood stasis. It is believed that blood stasis is the pathogenesis of this disease, so during the treatment period, promoting blood circulation to remove blood stasis is the main method, at the same time, different prescriptions should be used according to endometriosisⅠ, Ⅱand Ⅲ period respectively on the basis of menstrual cycle. 2 proven cases were listed in this paper.关键词：endometriosis;promoting blood circulation to remove blood stasis;treatment in different stages;endometriosis associated prescriptions;tonifying kidney and removing obstruction in the channels;tonifying kidney and strengthening original qi;experience of famous doctor
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发布时间：2022-08-31 - 摘要：This paper discusses the relationship between typhoid fever and febrile disease in perspective of the induction of febrile disease of TCM in Ganzheng Baofa. From the style and content of Ganzheng Baofa we can find that typhoid fever leading febrile disease, six meridians manipulating different diseases. We think that Ganzheng Baofa pay attention to clinical application and the changes of ancient and the time the author lived. The framework of Ganzheng Baofa is helpful for treating febrile disease in clinical application for us.关键词：Ganzheng Baofa;exogenous fever;febrile disease
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发布时间：2022-08-31 - 摘要：This paper explores the therapy and syndromes of impotence due to depression syndrome. It indicates that impotence cannot be restricted to the dogma of “decline of kidney and life gate fire”. Sorrow,anxiety,depression,terrified,abominate,timidity,frustrated,psychentonia,psychological pressure,hyperactivity of heart-fire and liver-fire,chronic fatigue,sub-health,and even bad environment are familiar causes of impotence. This kind of impotence caused by emotional changes all belong to impotence due to depression syndrome,and existed much more clinically. The expound of the therapy and syndromes of impotence due to depression syndrome by ancient Chinese medicine was detailed and abundant,but it doesn’t caused enough attention. The doctors need not only to understand the etiology and course by inquiry and listening and smelling examination,but also have an insight into the heart and realize the patient,and distinguish the form of depression. We could not blindly supplement essence only in the treatment,but also dispel melancholy,soothe the liver and relaxed,tonify spleen and embolden,regulate qi movement,and indicate the patient to aware kindly. The impotence due to depression syndrome is interlinked psychogenic erectile dysfunction of modern medicine.关键词：depression syndrome;impotence;dispel melancholy;tonify the kidney
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发布时间：2022-08-31 - 摘要：Through collecting and organizing the medical records of Professor Liu Jiaxiang treating lung cancer and by using data mining technology such as BK algorithom and entropy based complex systems, we study the related principle-method-recipe-medicinal features through such aspects as the basic formula for each TCM syndrome, the relationship between medicine and syndrome, the law of prescription composing. The aim of this study is to summarize and perfect Professor Liu’s experience of treating lung cancer to provide reference for the inheritance of experience of famous doctors and the development of thoughts of treating lung cancer by TCM, and at the same time we expect to open up new ideas for study the feature of drug using of prescriptions of famous doctors by using entropy based complex systems method.关键词：lung cancer;data mining;experience of famous doctors;Liu Jiaxiang
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发布时间：2022-08-31 - 摘要：In this paper data mining technology was used in study of using drugs regularity of Professor Zhu Huirong in treating colorectal cancer. Professor Zhu pays more attention to heat clearing and detoxifying, Kidney Tonifying and Phlegm Resolving, yin nourishing to moisten dryness in drug using. In clinical application, Professor Zhu usually uses the combination of cold medicine and warming medicine, and she is good at using drug pairs.
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发布时间：2022-08-31 - 摘要：This paper introduces Professor Huang Zhenqiao’s clinical experience in treating idiopathic thrombocytopenic purpura. It is said that this disease is essentially caused by spleen and kidney deficiency and reflected in the symptoms of superficial venule damage by liver fire. The key should be treating fire, qi and blood. A proven case is listed in this paper.关键词：idiopathic thrombocytopenic purpura;experience of famous doctor;Huang Zhenqiao
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发布时间：2022-08-31 - 摘要：This paper introduces the experience of Professor Wu Kunlun in treating functional bowel disorders with “Xiangsha Liujunzi Decotion” as basic prescription. Professor Wu made slight changes to the contents and dosage of the original prescription. 3 proven cases were listed in this paper.关键词：functional bowel disorders;“Xiangsha Liujunzi Decotion”;clinical experience;Wu Kunlun
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发布时间：2022-08-31 - 摘要：This article introduces chief physician Miao Qing’s treating experience of chronic cough in view of Shaoyang. Chief physician Miao Qing thinks that Xieyu Shaoyang, obstruction of cardinalate, the failure of lung to depress and descend as one of the important pathogenesis of chronic cough, and according to the pathological evolution of Shaoyang meridians Shaoyang cough can be divided into four aspects, which include:deficiency of Qi-blood, Xielian Shaoyang; Shaoyang Yubo, lung qi impairment; Shaoyang Danyu, intermingled phlegm and qi; Qiyu Huahuo, invasion of lung by fire. The patients with Shaoyang cough should be treated with the method of reconciling Shaoyang, lung dispersing and cough stopping.关键词：chronic cough;Shaoyang cough;TCM therapy;clinical experience;Miao Qing
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发布时间：2022-08-31 - 摘要：This article analyzes the rule of treating kidney disease combined with clinical practice. The early stage of nephronia is the yang-edema stage, which should be treated through diaphoresis and eliminating pathogen. Patients in this stage can be treated with Gancao Mahuang Decoction, Xiaoqinglong Decoction, Daqinglong Decoction, Yuebi Decoction, Mahuang Lianqiao Chixiaodou Decoction, etc. The intermediate stage is the ying-edema stage which should be treated through invigorating the spleen to alleviate water, and eliminating wind and consolidating superficies. Patients in this stage can be treated with Fangji Huangqi Decoction and Mufangji Decoction. The later stage is the deficient stage which should be treated through invigorating the kidney and warming yang. Patients in this stage can be treated with Zhenwu Decoction, Shenqi Pill, Shuyu Pill. The advanced stage is the toxin stage which should be treated through eliminating toxin and hydropoisoning by catharsis. Patients in this stage can be treated with Dachengqi Decoction, Tiaowei Chengqi Decoction and Zhuling Decoction,etc.关键词：kidney disease;classic prescription;clinical experience
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发布时间：2022-08-31 - 摘要：This paper discusses the treatment of asthma in view of six-meridian syndrome differentiation and correspondence between syndrome and prescription, and the application of syndrome and prescription, combined prescription were analyzed by proven cases.关键词：asthma;syndrome and prescription;classical prescription
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发布时间：2022-08-31 - 摘要：This article discusses He sizong’s academic thoughts in treating consumptive disease. He sizong considered that consumptive disease was caused by endogenous Zang-fu damage, and the medical pathogenesis was yin deficiency with syndrome of internal heat. He discussed the clinical mistreatment in detail, and criticized the contemporary doctor’s malpractices sharply. He putted forward the three key points of treating consumptive disease.关键词：consumptive disease;yin deficiency;academic thoughts;medication features;He sizong;He Xuan
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发布时间：2022-08-31 - 摘要：Objective:To compare the efficacy of individualized herbal decoction with Bronchiectasis Stabilization Decoction within a patient with stable bronchiectasis through N-of-1 RCT (Single case randomized controlled trial). MethodsThe lengths of observation period and washout period of a patient with stable bronchiectasis were determined by preliminary test, and then We conducted N-of-1 RCT (single-patient, double-blind, randomized, multiple crossover design) with 3cycles in 1 patient with stable bronchiectasis. The primary outcome was patient self-reported symptom scores on a visual analogue scale (VAS), 24-hour sputum volume and CAT (The COPD Assessment Test) scores were observed. Results:①After three rounds of trial, the symptom scores of the trial periods diminished significantly more than control periods (P<0.05),and the lower limit of the 95% confidence interval of the mean change was 1.53 (>0.5), indicating that the individualized herbal decoction has clinical superiority over the controlled decoction. ②After three rounds of trial, 24-hour sputum volume of the trial periods diminished significantly more than control periods (P<0.05). ③After three rounds of trial, the scores of CAT scale of the trial periods diminished significantly more than control periods (P<0.05),indicating better quality of life in the trial periods. Conclusion:N-of-1 RCT reflected the advantage of TCM individualized treatment in this patient with stable bronchiectasis, it also provided with the highest rank of evidence of evidence-based medicine for this patient.关键词：bronchiectasis;N-of-1 RCT;individualized treatment;traditional Chinese medicine
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical effect on changes of serum IgE, T lymphocytes and pulmonary function of bronchial asthma patients, and explore the action mechanism of “Fujiu Sticking” in preventing and treating bronchial asthma. Methods60 cases of bronchial asthma patients were divided into treatment group and control group equally, and treated with “Fujiu Sticking” and “Sanfu Sticking” respectively. The changes of serum IgE, T lymphocytes and pulmonary function were observed. Results:①The levels of CD4+ increased(P<0.05)and CD8+ decreased(P<0.05)after the treatment and there was significance in the levels of CD4+ and CD8+ in the two groups(P<0.05). ② After the treatment , the serum IgE of the two groups decreased obviously than before(P<0.05), and the treatment group was lower than that of control group(P<0.05). ③There was no significant difference in FEV1and FEV1/FVC in the two groups before and after treatment(P>0.05). Conclusion:“Fujiu Sticking” has curative effect on increasing immunity and decreasing allergic reaction in bronchial asthma patients in chronic persistent period.关键词：bronchial asthma;“Fujiu Sticking”;“Sanfu Sticking”;immune function;allergic reaction
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of “Shenque” acupoint external application with “Xiaozhong Powder” in treatment of liver cirrhosis ascites. Methods60 cases of patients with liver cirrhosis ascites were randomly divided into treatment group and control group,30 cases in each group. The control group was treated with conventional western medicine,while the treatment group was treated with “Shenque” acupoint external application with “Xiaozhong Powder” based on the treatment of control group. Two groups were treated for 14 days. The changes of abdominal water scale dividing,abdominal distension VAS score,liver function were compared. Results:①Compared before and after the treatment,the difference of abdominal water scale dividing of two groups were statistically significant(P<0.05)；after the treatment,the difference of abdominal water scale dividing between two groups was significant(P<0.05), and the treatment was better than the control group. ②Compared before and after the treatment,the difference of abdominal distension VAS score of two groups were statistically significant(P<0.05)；after the treatment,the difference of abdominal distension VAS score between two groups was significant(P<0.05). ③Compared before and after the treatment,the difference of liver function of two groups were statistically significant(P<0.05)；after the treatment,there was no significant difference of liver function between two groups(P>0.05). Conclusion:The effect of “Shenque” acupoint external application with “Xiaozhong Powder” in treatment of liver cirrhosis ascites was satisfying；it can reduce abdominal water scale significantly.关键词：liver cirrhosis ascites;“Xiaozhong Powder”;“Shenque” acupoint;external application;liver first-pass effect
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical curative effect of “Danshao Shugan Granule” for the treatment of nonalcoholic fatty liver disease. MethodsWe selected 80 cases of nonalcoholic fatty liver patients which were randomly divided into treatment group(40 cases)and control group. The treatment group was treated with “Danshao Shugan granule” and the control group was treated with Atorvastatin Tablets.The period of treatment was 3 months.The clinical efficacy, syndrome score, the changes of blood lipid and liver function were observed in the two groups. Results:①The total effective rate of the treatment and control groups were 90.0% and 85.0% respectively, and there was no significant difference in efficacy between the two groups (P>0.05). ②After treatment,the symptom score was obvious reduced in the treatment and control group compared with those before treatment(P<0.05) . ③After the treatment, the levels of serum total cholesterol and triglyceride were obviously decreased than before(P<0.05)and the level of control group was lower than that of treatment group; ALT, AST and GGT was decreased in the treatment group compared with those before treatment(P<0.05) and lower than that of control group. Conclusion:“Danshao Shugan Granule” has certain therapeutic effect for nonalcoholic fatty liver disease, and could improve lipid metabolism and protect liver function.关键词：nonalcoholic fatty liver;“Danshao Shugan Granule”;blood lipid;liver function
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发布时间：2022-08-31 - 摘要：Objective:To study the effect of “Ye’s renal failure Party A” in the treatment of chronic renal failure. Methods3 and 4 period of 60 cases of patients with chronic kidney disease were selected and randomly divided to control group and treatment group, 30 in each group. The patients in control group were treated with normal western medicine, while the treatment group was added “Ye’s renal failure Party A” on the basis of normal western medicine treatment. After 6 months treatment, we observed two groups of patients with TCM syndrome score, 24 hours urine protein, therapeutic efficacy, renal function, serum TGF beta 1. Results:①The total effective rate of the treatment group were 93.33% and the control group were 53.33% respectively. The treatment group TCM syndrome score decreased more significantly than the control group (P<0.05). ②TCM syndrome score in the treatment group decreased significantly (P<0.05), while the score in the control group did not decrease significantly (P>0.05) after the treatment. The difference between the groups, TCM syndrome score in the treatment group decreased more significant than the control group (P<0.05). ③Compared before and after treatment, the two groups of 24 h urinary protein were significantly decreased (P<0.05). Between two groups, 24 h urinary protein in the treatment group decreased more significantly than the control group (P<0.05) after the treatment. ④There was no significant difference in UA and BUN in each group before and after treatment (P>0.05); Scr in treatment group was significantly decreased (P<0.05) and eGFR was significantly increased (P<0.05). There were significant differences in Scr and eGFR between the two groups, and the improvement degree of the treatment group was better than the control group (P<0.05). ⑤The serum levels of TGF-β1 were significantly decreased in the treatment group (P<0.05), while there was no significant difference in control group (P>0.05). Compared between the two groups after the treatment, the difference was statistically significant between the serum levels of TGF-β1(P<0.05). Conclusion:“Ye’s renal failure Party A” in the treatment of 3 and 4 chronic kidney disease has obvious curative effect, including reduction proteinuria, improvement renal function and prevention of renal fibrosis.关键词：chronic renal failure;3 and 4 phase;“Ye’s renal failure Party A”;renal insufficiency;renal fibrosis
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical effects of “Jianpi Huoxue Decoction” on treating lipid metabolism disorder after menopause. Methods50 patients were randomly divided into observation group and control group, 25 in each group. The control group was treated with Simvastatin Tablets and the observation group was treated with “Jianpi Huoxue Decoction”, with 3 months of treatment peoriod. The changes of blood lipid, sex hormone and body weighty were observed. Results:Intra-group comparison before and after the treatment, there was significance in TC, TG and LDL-C(P<0.05)but there was no significance in HDL-C(P>0.05)；comparsision between groups after treatment, there was significance in TC and LDL-C(P<0.05). Intra-group comparison before treatment, there was significance in E2 level and body weighty in observation group(P<0.05), but there was no significance in each index in control group(P>0.05); comparsision between groups after treatment, there was significance in E2 level and body weighty(P<0.05). Conclusion:the effect of “Jianpi Huoxue Decoction” on treating lipid metabolism disorder after menopause was satisfactory.关键词：after menopause;lipid metabolism disorder;“Jianpi Huoxue Decoction”
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发布时间：2022-08-31 - 摘要：Objective:To observe the effects of ironing treatment at “Zusanli” on the intestinal function in senile patients with colorectal cancer after laparotomy. Methods72 senile patients over 65 years old were randomly assigned to iron-treated group (36 cases) and control group (36 cases), “Iron Sticking” and Placebo Sticking was treated respectively, with course of 3 days. The time of bowel sound recovery and the first aerofluxus and dejection were recorded. The fasting venous blood samples were gathered before and 3 days after surgeries, testing IL-2, IL-6, NK cells, CD4+/CD8+ ratio and so on. Results:①The time of bowel sound recovery and the first aerofluxus and dejection in iron-treated group was shorter than that of control group after treatment (P<0.01). ②The IL-2, CD4+/CD8+ levels of iron-treated group increased than before (P<0.01), and IL-6 level decreased than before (P<0.01); and there was significance in levels of IL-6 and CD4+/CD8+ between the two groups (P<0.01). Conclusion:Iron treatment at bilateral “Zusanli” could accelerate the restitution of borborygmi in postoperative senile patients with colorectal cancer after laparotomy, promote the anal discharge, its mechanism may be association with regulating inflammatory factors and immune function.关键词：colorectal cancer;laparotomy;“Zusanli” acupoint;intestinal function;ironing treatment;senile patients
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of “Pinggan Huoxue Decoction” in treating liver-depression and blood-stasis insomnia accompanied by hypomnesis. MethodsSeventy-two subjects were randomly divided into treatment group and control group, 36 cases in each group. The control group was treated with Wuling Capsule, and treatment group was added with “Pinggan Huoxue Decoction”, with the course of 12 weeks. The improvement of the sleep were decided by SPIEGEL scale score and assessed by P300 changes to contrast. Results:After treatment, SPIEGEL scale score of the two groups were reduced(P<0.05), and the treatment group was lower than the control group (P<0.05); “Pinggan Huoxue Decoction” exhibits a distinguish efficacy on P300 after the treatment than before in treatment group(P<0.01), and the treatment was shorter than the control group(P<0.05). Conclusion:“Pinggan Huoxue Decoction” has an advantage in improving memory and sleep in the treatment of insomnia.关键词：insomnia;hypomnesis;“Pinggan Huoxue Decoction”;SPIEGEL scale;event-related potentials(ERPs)
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical effect of syndrome differentiation acupuncture therapy on chronic migraine. Methods200 patients of chronic migraine were randomized into treatment group and control group,100 cases in each group. The treatment group was treated with syndrome differentiation acupuncture therapy,while control group was treated with conventional western medicine. The treatment course was 46 days in each group,with a follow-up of 2 weeks. Clinical efficacy was observed. Changes of chronic migraine score,incubation and amplitude of SSR were compared. Results:①180 cases completed the trail,among which 94 cases in treatment group and 86 cases in control group. ②The total effective rate of treatment group and control group were 92.55% and 84.88%. The difference of clinical efficacy was statistically significant(P<0.05). ③Compared before and after the treatment,the total chronic migraine score in each group was obviously decreased(P<0.05), while the total chronic migraine score in treatment group decreased obviously than that of control group after the treatment(P<0.05). ④Compared before and after the treatment,incubation of SSR in the two groups were shot than before(P<0.05), and amplitude of SSR in treatment group increased obviously(P<0.05). After the treatment,the difference of incubation and amplitude of SSR was statistically significant(P<0.05). Conclusion:The effect of syndrome differentiation acupuncture therapy on chronic migraine was satisfying. It can relieve the headache significantly with a possible mechanism of improving autonomic nervous system function.关键词：migraine;chronic;acupuncture;syndrome differentiation and treatment;autonomic nervous pathway;sympathetic skin reflex
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发布时间：2022-08-31 - 摘要：This paper introduces 3 cases of treating cough with Smoking therapy in Compendium of Materia Medica, and discusses three herbs Flos Farfarae, Radix Rehmanniae Preparata and cudweed and analyzes the development of Sanqi Powder. A proven case was listed in this paper.关键词：cough;smoking therapy;Compendium of Materia Medica;Sanqi Powder;proven case
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发布时间：2022-08-31 - 摘要：Objective:To observe the effects of artemisinin on cardiac function and fibrosis in diabetic cardiomyopathy rats. MethodsEight Wistar rats were randomly selected as normal group, and the other rats were created as diabetic models by intraperitoneal injection of streptozotocin. After 16 weeks, the diabetic models were set up successfully after the test, and were randomly divided into diabetic cardiomyopathy group and artemisinin group, 8 in each group. Each group was intervened respectively. The myocardial pathology structure was observed by HE staining. The content of collagen was detected by Masson staining, and cardiac function was measured by Echocardiography. Results:Compared with normal group, the expression of fibrosis increased obviously in diabetic cardiomyopathy group(P<0.01), and E/A, LVEF and FS decreased obviously, and cardiac systolic and diastolic function decreased obviously. Compared with diabetic cardiomyopathy group, the expression of fibrosis decreased obviously(P<0.01), E/A, LVEF and FS increased(P<0.01), and cardiac systolic and diastolic function improved obviously. Conclusion:Artemisinin may improve cardiac function of rats by attenuate myocardial fibrosis.关键词：artemisinin;diabetes cardiomyopathy;cardiac function;fibrosis
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发布时间：2022-08-31 - 摘要：Objective:To explore the influence of Puerarin(Pur) on expression of gene andprotein of ATP-binding cassette superfamily G member2(ABCG2) in human renal proximal tubular epithelial cells(HK2),and to clarify Pur the possible mechanism for the treatment of gout. MethodsHK2 cells were cultured in vitro,and were divided into control group and 25, 50 , 100, 200 mg/L Pur dose groups. CCK-8 method was used to detect Pur effects on HK2 cells; ATP content was detected, HK2 cells enzymatic reaction condition was observed; Fluorescence quantitative PCR and Western blotting methods were used for determination HK2 ABCG2 gene protein expression in the control group and the different dose groups. Results:Pur has promote proliferation effect on HK2 cells(P<0.05). The best group of ATP activity was 100 mg/L in dose group; detection by Real-time PCR and Western blotting methods showed that HK2 cells ABCG2 gene and protein expression in dose group was significantly higher than that of the control group,of which 100 mg/L of dose group was most obvious(P<0.01). Conclusion:Pur could increase HK2 cells the expression of ABCG2,which indicated that this maybe one of the important molecular mechanism for regulation gout patients blood uric acid level.关键词：Puerarin;gout;human renal proximal tubular epithelial cells;ATP-binding cassette superfamily G member 2
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发布时间：2022-08-31 - 摘要：Objective:To investigate the protective effect on myocardium of three commonly used tonifying qi traditional Chinese medicine including ginseng, astragalus and liquorice in mice with acute myocardial injury induced by adriamycin. MethodsModel of acute myocardial injury was induced by adriamycin with intraperitoneal injection. Mice were randomly assigned to normal group, model group, astragalus group (10 g/kg), ginseng group (3 g/kg) and liquorice group (3 g/kg). Ginseng, astragalus and liquorice were given orally to mice continuously for 15 days starting at 4 days before modeling. The serum levels of myocardial enzymes including creatine kinase (CK), lactate dehydrogenase (LDH), and aspartate aminotransferase (AST), and the left ventricular histopathology were measured. The effect of anti-oxidative stress was detected and the cardiac energy metabolism was quantitatively determinated with HPLC method. Results:Compared with that in the normal group, the serum activities of myocardial enzymes were significantly increased, the myocardium had large area of edema, muscle fiber of vacuolization, the activities of antioxidant enzymes were decreased and myocardial energy metabolism was abnormal in the model group. Compared with that in the model group, the serum activities of myocardial enzymes in the ginseng, astragalus and liquorice groups were decreased significantly, and myocardial edema was alleviated. And ginseng and astragalus could improve the activity of GSH-Px. The three tonifying qi traditional Chinese medicine could improve myocardial energy metabolism slightly, among them the function of astragalus was the strongest, and the next was that of ginseng. Liquorice had a significant effect on increasing the concentration of cAMP of myocardial tissue. Conclusion:In conclusion, Ginseng, astragalus and liquorice have protective effect on acute myocardial injury induced by adriamycin in mice, and the function may be related to the regulation of myocardial energy metabolism and the increase of the activities on antioxidant enzymes. The significant trend of astragalus is regulating energy metabolism, and the antioxidant effect of ginseng and astragalus is remarkable. The effect of liquorice on increasing the concentration of cAMP is significant.关键词：ginseng;Astragalus;liquorice;Adriamycin;myocardial injury
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发布时间：2022-08-31 - 摘要：Objective:To study antidepressant effects of “Compound Danshen Dripping Pill” (FDD) on lipopolysaccharide (LPS)-induced depressive-like behaviors in mice. MethodsTo observe the influence of FDD high dosage (270 μg/g) and low dosage (135 μg/g) on open field test (OFT) and forced swim test (FST) in depressive-like behavior model mice induced by LPS injection, furthermore, to detect interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10) levels in serum and cerebral cortex, explain antidepressant mechanism of FDD from its effects on inflammatory cytokines in depression model. Results:High dosage of FDD can obviously improve the decrease of moving distances in OFT induced by LPS injection, and both of high and low dosage of FDD can remarkable increase the decreasing of rearing times induced by LPS, as well as decrease the improvement of immobility time of mice in FST induced by LPS. All of these results are statistically significant (P<0.05). In serum, each dosage of FDD can significantly reduce IL-6, TNF-α level improvement, and increase IL-10 decrease induced by LPS with statistically significant (P<0.05, P<0.01). In cerebral cortex, each dosage of FDD can significantly reduce IL-6 level improvement induced by LPS (P<0.01), high dosage of FDD can obviously reverse the improvement of TNF-α level induced by LPS (P<0.05), and both of high dosage (P<0.01) and low dosage (P<0.05) can obviously reverse IL-10 level increase. Conclusion:The improvement effects of FDD on depressive-like behaviors mice model induced by LPS may be related to its anti-inflammation and immune system regulation effects, and its mechanism needs further research.关键词：Compound Danshen Dripping Pill (FDD);LPS;depression;IL-6;TNF-α;IL-10
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发布时间：2022-08-31 - 摘要：Objective:To investigate the chemical compounds from the branch of Syringa wolfii C. K. Schneid. MethodsThe branch was subjected to the system solvent, and the obtained extracts were separated by column chromatography and thin layer chromatography. The volatile oil was extracted by water-steam distillation and analyzed by GC-MS. Results: Six chemical compounds were identified, which included dimethyl terephthalate (1), 3-hydroxy-Ursane- 12-ene (2), ursolicacid (3), 4- (2-hydroxyethyl)-phe-nol (4), D-mannitol (5) and syringin (6). 69 compounds were identified in essential oils, accounting for 99.86% of the total essential oil and 2-methyl-5- (1-methyl ethyl)-1-cyclopentene alcohol (14.16%) was with the high content among them. Conclusion:Compound 3,5 and 6 were obtained for the first time from the plant. Compound 1,2 and 4 were obtained in Syringa for the first time. Because the contents of 2 and 4 were fairly high, which will provide protophase theoretical reference for the gathering of the two compounds from Syringa wolfii C. K. Schneid. Except for the alkanes, the most compounds were terpene. The analysis of the results show that sesquiterpenes was accounted for the largest portion in the alkene and the oxide compounds.关键词：Syringa wolfii C. K. Schneid;chemical composition;GC-MS;essential oils
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发布时间：2022-08-31 - 摘要：This paper reviews the pharmacological activity of traditional Chinese medicine composite polysaccharide. Complex polysaccharides have anti-tumor,immunomodulatory,hypoglycemic,anti-viral,anti-oxidation,anti-radiation,antibacterial and so on,polysaccharide complex polysaccharides pharmacological activity than a single high in traditional Chinese medicine,and showed synergy.关键词：polysaccharide;complex polysaccharides;pharmacological activity
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发布时间：2022-08-31 - 摘要：This paper briefly reviews the research progress of mechanism of acupuncture information in the initiation and conduction on acupoint and its correlation with mast cells. After needle inserting at the acupoint, the material basis, mechanical reaction force, inflammatory response, nerve excitement, substance P, tissue fluid, calcium, Histamine, etc all taking part in the conduction of acupuncture information and activating the mast cells’ degranulation. Degranulation of the mast cells maybe the key in the conduction of acupuncture information in the initiation and conduction.关键词：acupuncture;mast cells;information conduction;initiation;mechanism;review
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发布时间：2022-08-31
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