最新刊期

    2 2016
    • ZHOU Hai-zhe
      Vol. 50, Issue 2, Pages: 1-3(2016)
      摘要:This paper introduces professor Zhang’s experience in treating the throat disease. Professor Zhang identifies this disease as five types which include external evil invasion, phlegm-qi knot, yin deficiency of lung and kidney, spleen-stomach overheat, and deficiency-fire flaming upward due to spleen deficiency. The main treatment methods for throat diseases are provided as disparsing wind and clearing heat, removing toxin and easing the throat, regulating qi and relieving depression, resolving phlegm and easing the throat, nourishing yin-fluid and moistening dryness, clearing heat toxin, easing the throat to reduce swelling, invigorating spleen and replenishing qi, clearing fire to ease the throat. These are flexibly combined and applied with syndromes.  
      关键词:throat disease;syndrome differentiation and treatment;experience of famous doctors;Zhang Xuewen   
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      发布时间:2022-08-31
    • JIANG Jian
      Vol. 50, Issue 2, Pages: 4-7(2016)
      摘要:This paper explores the therapy and syndromes of tinnitus due to depression syndrome. It indicates that tinnitus cannot be restricted to the dogma of “the kidney opening into the ears”,and also cannot invigorate kidney totally. Tinnitus is a common manifestation of depression syndrome,ancient physicians had expounded it sufficiently. Depression,anger,anxiety,panic can all lead to tinnitus. Tinnitus due to depression syndrome has direct clinical evidences(emotional disorders’ mind and psychotic and neurologic symptoms),as well as indirect clinical evidences further(involved colorful constitutional symptoms). Tinnitus due to depression syndrome is a kind of masked depression syndrome which concealed by the tinnitus essentially. The objective existence of tinnitus due to depression syndrome has been proved by modern pathophysiology,psychology,and therapeutics of traditional and western medicine already. To improve the clinical curative effect,we should consider the intractable tinnitus again from the view of depression syndrome,and try to treat it from the aspect of depression syndrome.  
      关键词:depression syndrome;tinnitus;clinical features;treating from the aspect of depression   
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      发布时间:2022-08-31
    • CAO Qi,ZHOU Li-rong,WANG Wen-jun
      Vol. 50, Issue 2, Pages: 8-11(2016)
      摘要:To illuminate the diagnosis, classification and theuapeutic strategies of polycystic ovary syndrome (PCOS) proposed by Professor Yu Jin,this paper explained her exploration on the pathogenesis of PCOS with different viewpoints of “Kidney deficiency and phlegm” (in Traditional Chinese medicine, TCM), hyperandrogenitism being the main reason (in Modern medicine, MM) and both factors being the same cut-point for dysregulation of the female life network (in the fusion or the integration of TCM and MM). Professor Yu innovatively set up the diagnosis of “small follicle syndrome (anovulatory mense disorder and PCO, without hyperandrogenitism)”. She treated the two syndromes with the combination of psychological-biological-socieological strategies. The treatment for PCOS is mainly to cutdown the hyperandrogenitism and recover the normal ovarian axis, while for “small follicle syndrome” being to improve the lowered ovarian function.  
        
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      发布时间:2022-08-31
    • DI Dan,ZHOU Min,ZHOU Hui-lin,QIN Peng-fei,ZHU Wei
      Vol. 50, Issue 2, Pages: 12-14(2016)
      摘要:This paper is on the development of portable tongue imagine analysis instrument on the basis of pervious research. In the environment of simulating the natural lighting, this instrument collecting tongue imagines with digital imaging equipment, then extracting the features of the tongue imagines, reporting the results of tongue analysis. With small size, easy carrying, this instrument can be used to collect tongue imagines of patients of lying on bed.  
      关键词:tongue diagnosis;tongue imagine analysis instrument;portable   
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      发布时间:2022-08-31
    • WANG Qing-qi,YAO Yi,FEI Xiao-yan,WANG Xiu-wei,ZOU Chun-pu,LI Hai-feng,WANG Li-hui
      Vol. 50, Issue 2, Pages: 15-18(2016)
      关键词:chronic colitis;intestinal polyps;chronic gastritis;teaching ward round   
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    • ZHAO Fei-yi,XU Hong
      Vol. 50, Issue 2, Pages: 19-22(2016)
      摘要:This paper introduces clinical experience in differentiating and treating past-schizophrenia depression by soothing the liver and regulating the circulation of qi and occupational therapy. It is argued that the disease is caused by seven emotions and overacting of five minds. Past-schizophrenia depression should be treated by soothing the liver and regulating the circulation of qi combined with occupational therapy, and excellent results have been achieved in clinics. One proven case was presented.  
      关键词:past-schizophrenia depression;soothing the liver and regulating the circulation of qi;occupational therapy   
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      发布时间:2022-08-31
    • AN Song-ge,ZOU Wen-shuang,CHANG Pan-pan,LIU Tie-jun
      Vol. 50, Issue 2, Pages: 23-25(2016)
      关键词:Liu Tiejun;liver cirrhosis ascites;“Qixiao Yin Decoction”;proven case   
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    • ZHANG Qian,ZHANG Yan
      Vol. 50, Issue 2, Pages: 26-27(2016)
      摘要:The paper is to introduce Zhang Yan’s experience in treating sweating disease. It is viewed that sweating disease can be cured though such therapies as warming yang, tonifying spleen, nourishing heart,etc.Two proven cases are presented.  
      关键词:sweating disease;clinical experience;Zhang Yan   
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    • MIAO Ting-ting,CHEN Guang-dong
      Vol. 50, Issue 2, Pages: 28-30(2016)
      摘要:This paper introduces the clinical experience of the treatment of psoriasis by Professor Huang Huang. Professor Huang Huang makes a flexible and dialectical analysis by using the “theory of correspondence of prescription and syndrome” and the “constitutional theory of classical prescriptions”. In this paper, we summarize the constitutions of classical prescriptions and the responding syndromes he used in treating chronic psoriasis.  
      关键词:psoriasis;classical prescriptions;clinical experience;Huang Huang   
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      发布时间:2022-08-31
    • WANG Jing,XU Jin-kang
      Vol. 50, Issue 2, Pages: 31-33(2016)
      摘要:In this paper, we analyzed the proven cases of wood restricting earth class in Medical Records for Clinical Guidance, and according to the physiological relation between wood and earth, we summarized the relationship between stomach disease the liver and the special experience of Ye’s treating stomach disease from liver, that are:to modify the prescription according to the anti-pathogenic factors and pathogenic factors, deficiency and excess of original and superficial causes on the basis of treating liver and stomach together; to lay emphasis on complying with physiological property of Zang and Fu to recover their function in the usage of medication.  
      关键词:Medical Records for Clinical Guidance;wood restricting earth;academic thought   
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      发布时间:2022-08-31
    • CHEN Hai-jing,SHI Zhe-xin
      Vol. 50, Issue 2, Pages: 34-35(2016)
      摘要:The sentence of “Observe symptoms to know how it committed against, and then follow the legislation to treat syndromes” shows the idea and process of diagnosis of Treatise On Febrile Diseases, and it is the collection of pulse and symptoms, embodies the dialectical thinking and methods of “pulse–certificate”. It is also the prototype of syndrome differentiation and treatment, laying a solid foundation for the establishment of TCM syndrome differentiation and treatment. At the same time, it also shows that “recognize pulse and symptoms”, “identify pulse and symptoms” occupies an important position in the clinical syndrome differentiation of TCM.  
      关键词:“observe symptoms”;“know how it committed against”;“follow the legislation to treat syndromes”;study of the connotation   
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      发布时间:2022-08-31
    • ZHOU Sheng-fang,LIU Ru-xiu,LIU Jin-feng
      Vol. 50, Issue 2, Pages: 36-37(2016)
      关键词:rheumatic heart disease;heart failure;benefiting qi for diuresis;clinical experience;Liu Ruxiu   
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    • FANG Qing-xia,ZOU Ping,CHEN Rui-xue,CHEN Da-qi
      Vol. 50, Issue 2, Pages: 38-41(2016)
      摘要:Objective:To observe the clinical effect of Chen’s Bushen Huoxue Decoction combined with acupoint catgut embedding for treatment of kidney deficiency and blood stasis type of premature ovarian failure. Methods76 cases of patients with premature ovarian kidney deficiency and blood stasis were randomly divided into treatment group and control group, 38 cases in each group. The treatment group was treated with Chen’s Bushen Huoxue Decoction combined with acupoint catgut embedding therapy, control group were treated with sequential therapy of estrogen and progesterone. Two groups of treatment course were 3 menstrual cycle. The clinical efficacy and safety were observed, the peri menopausal symptom score (Kupperman score) and related follicle stimulating hormone (FSH), LH and estradiol (E2) changes were compared.  Results:①The clinical total effective rate of the treatment group and the control group were 89.47% and 76.32% respectively; there were statistically significant difference in the clinical efficacy of the treatment group and the control group (P<0.05). ②The Kupperman score in each group was significantly decreased before and after the treatment (P<0.05). The difference between the two groups before and after treatment, the score of the treatment group was significantly lower than the control group (P<0.05). ③Before and after treatment, the levels of LH and FSH were significantly lower in the two groups, while the levels of E2 were significantly increased (P<0.05); the level of LH, E2 and FSH were significantly different between the two groups, the improvement of the treatment group was better than that of the control group (P<0.05). ④The occurrence rate of adverse reactions of the two groups were compared, the difference was statistically significant (P<0.05).  Conclusion:There are good curative effects of Chen’s Bushen Huoxue Decoction combined with acupoint catgut embedding in treatment of kidney deficiency and blood stasis of premature ovarian failure, and with fewer side effects.  
      关键词:premature ovarian failure;kidney deficiency and blood stasis;Chen’s Bushen Huoxue Decoction;acupoint catgut embedding;hormone   
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      发布时间:2022-08-31
    • YU Chao,CAO Hong-wen,FENG Yi-geng,HE Xiao-feng,SUN Peng,CHEN Lei
      Vol. 50, Issue 2, Pages: 42-44(2016)
      摘要:Objective:To observe the clinical efficacy of “Jianfu Yin” with Viagr in the treatment of LOH intractable ED. Methods60 cases were randomized into treatment group and control group, 30 in each group. The control group was treated with “Zuogui Pill” combined with Viagr, and the treatment group was treated with “Jianfu Yin” combined with Viagr,both groups with the course of 2 months.The rigidity of penis levels, scores of IIEF-5 scores and SILOH were observed.  Results:① After the treatment of 2 months, there were 22 cases reached III level in treatment group and 17 cases in control group; there was significant difference in the comparison of rigidity of penis between the two groups(P<0.05), and the treatment group was better than the control group. ② Compared before and after the treatment in each group, the scores of IIEF and SILOH both obviously increased(P<0.05); while compared before and after the treatment between the two groups, score of IIEF in treatment group higher than that of control group, and the difference was significant(P<0.05).  Conclusion:The clinical efficacy of “Jianfu Yin” with Viagr in the treatment of LOH intractable ED was satisfactory.  
      关键词:late-onset hypogonadism in male(LOH);erectile dysfunction(ED);integrated Chinese and western medicine;“Jianfu Yin”;Viagr   
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      发布时间:2022-08-31
    • LIN Jian-xiang,ZENG Su-e,YE Zhong-huan,TAN Zhao-hui
      Vol. 50, Issue 2, Pages: 45-48(2016)
      摘要:Objective:To observe the clinical therapeutic effect on ankylosing spondylitis of damp-heat obstruction type by “Nanshe Simiao Decoction” combined with functional exercises. Methods64 ankylosing spondylitis patients of damp-heat obstruction type were randomly divided into treatment group and control group, 32 in each group. Treatment group was given self-made “Nanshe Simiao Decoction” accompanied by functional exercises; control group was given salfasalazine capsules orally. Total course of treatment was 3 months for the two groups. Standard-reaching rate for curative effect was recorded, and changes in clinical symptom indices (duration of morning stiffness, spinal pain score,spinal inflammation score,overall patient evaluation and BASFI index), spinal mobility index (finger to floor distance, occiput to wall distance, chest expansion and Schober test) and relevant biochemical indices (CRP, ESR, blood routines, liver and kidney function) were compared.  Results:①Standard-reaching rate of curative effect in treatment group and control group was 78.13% and 56.25% respectively; there was statistical significance in the difference of inter-group curative effect(P<0.05). ②Comparison inside groups before and after treatment, duration of morning stiffness, Spinal pain score,Spinal inflammation score,Overall patient evaluation and BASFI index were all significantly decreased, difference being statistically significant(P<0.05).Comparison between groups after treatment, above-mentioned indices decreased more significantly in treatment group than that in control group(P<0.05). ③Inside-group comparison before and after treatment, all differences but occiput to wall distance in control group(P>0.05), occiput to wall distance in treating group(P<0.05) are statistically significant(P<0.05). Inter-group comparison after treatment:there are statistical significance in differences of finger to floor distance, chest expansion and distance of Schober test(P<0.05). ④There were no obvious abnormality in blood routines, liver and kidney function test. At the same time, both CRP and ESR levels lower significantly, according to the comparison inside group before and after treatment(P<0.05); CRP and ESR level in treating group descend more significantly than that in control group after treatment(P<0.05).  Conclusion:Clinical symptoms can be significantly relieved, spinal and joint function can be improved by “Nanshe Simiao Decoction” accompanied by functional exercises.  
      关键词:ankylosing spondylitis;damp-heat obstruction;“Nanshe Simiao Decoction”;functional exercise;pain;spinal mobility   
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      发布时间:2022-08-31
    • GAO Qiang,WU Chao,XI Ming-jian,TIAN Xun-dong,QIAO Qi
      Vol. 50, Issue 2, Pages: 49-51(2016)
      摘要:Objective:To observe the clinical effect of warming needle moxibustion by thunder fire on treating knee osteoarthritis with wind-cold arthralgia syndrome. Methods120 cases of knee osteoarthritis in wind-cold arthralgia syndrome were randomly divided into treatment group and control group, 60 cases for each group. Treatment group were treated with warming needle moxibustion by thunder fire, and control group received Glucosamine Hydrochloride Tablets. The therapeutic effect and levels of Visual analogue scale (VAS), Fairbank scores and Lysholm scores were detected respectively after 30 days treatment course.  Results:The total effective rate was 93.33% in the treatment group, significantly higher than 66.67% in the control group (P<0.05). The levels of VAS were significantly lower (both P<0.05), while the levels of Fairbank scores and Lysholm scores were significantly higher (both P<0.05) in both groups after treatment, but the levels of VAS, Fairbank scores and Lysholm scores in the treatment group were better than the control group (all P<0.05).  Conclusion:Warming needle moxibustion by thunder fire can significantly reduce knee pain and improve knee function and alleviate the condition in knee osteoarthritis with wind-cold arthralgia syndrome.  
      关键词:knee osteoarthritis;wind-cold arthralgia syndrome;warming needle moxibustion;thunder-fire moxibustion   
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      发布时间:2022-08-31
    • LIANG Zhi-qiang,LI Ji,ZHAO Cheng,CAO Ye-min,XI Jiu-yi
      Vol. 50, Issue 2, Pages: 52-54(2016)
      摘要:Objective:To observe the clinical effects of “Qingying Huayu Granule” in treating acute superficial thrombophlebitis. Method 80 patients with acute superficial thrombophlebitis were randomly divided into treatment group and control group, 40 cases in each group. The treatment group was treated with “Qingying Huayu Granule”, while the control group was treated with Tong Sai Mai Tablet, with the course of 30 days for two groups. The clinical effect and the related biochemical index(WBC, TNF-α, CRP and IL-6) were observed.  Results:①The clinical total effective rate of the treatment group and the control group were 92.50% and 80% respectively, and the curative effect of the treatment group was better than that of the control group(P<0.05). ②Compared before and after the treatment, the levels of TNF-α, CRP, and IL-6 were significantly decreased in each group (P<0.05); after treatment, the levels of IL-6, CRP and TNF-αin the treatment group were significantly lower than those in the control group (P<0.05).  Conclusion:“Qingying Huayu Granule” was effective on treating superficial thrombophlebitis in acute period, and the possible mechanism is dissolving and reperfusing venous thrombosis by regulating the inflammation coagulation network.  
      关键词:superficial thrombophlebitis;green-blue snake toxin sore;acute phase;“Qingying Huayu Granule”;blood stasis;coagulation and inflammation network   
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    • XU Hui-xiang,WANG Zhong-min,WANG Ming-chuang
      Vol. 50, Issue 2, Pages: 55-58(2016)
      摘要:Objective:To observe the effect of “Qiangli Zengyi Soup” on brain fatigue associated with memory deterioration. Methods152 patients with brain fatigue associated with memory deterioration were randomly divided into treatment group and control group, 76 in each group. The treatment group was treated with “Qiangli Zengyi Soup” while the control group was treated with Baizi Yangxin Pills, with the course of 10 weeks for two groups. The clinical effects were detected, and the score of clinical syndrome and the related index of memory were compared.  Results:① The total effective rate of the treatment group and control group was 93.42% and 82.89% respectively; there was significant difference in the clinical efficacy between the two groups(P<0.05). ②Compared in each group before and after the treatment, each index and total integral in each group were significantly declined, and the difference was statistically significant (P<0.05). ③Compared in each group before and after the treatment, scores of picture memory, reorganization, association, understanding and remembering, total score and MQ scores were significantly increased in treatment group (P<0.05), while in control group the cores of association, understanding and remembering, total score and degree of MQ score increased significantly(P<0.05). After the treatment, the scors of remember pictures, recognition, total score and degree of MQ score increased more significantly in treatment group than that in control group(P<0.05).  Conclusion:The clinical effect of “Qiangli Zengyi Soup” on brain fatigue associated with memory deterioration was satisfactory in relieving brain fatigue andstrengthen memory.  
      关键词:brain fatigue;memory deterioration;“Qiangli Zengyi Soup”;Patent Chinese medicine;Wechsler memory scale   
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      发布时间:2022-08-31
    • LI Xiao-xin,MA Jian-feng,SHAO Zhou-xiang
      Vol. 50, Issue 2, Pages: 59-61(2016)
      摘要:Objective:To observe the effect on cytokines and hemorrheology of Yangyin Qingre Huoxue recipe in treatment of the patients with recurrent aphthous ulcer. Methods126 cases of patients with recurrent aphthous ulcer were randomly divided into the observation group (65 cases), and the control group (61cases). The control group was treated with Cetylpyridinium chloride buccal tablets, the observation group was treated with Cetylpyridinium chloride buccal tablets Yangyin Qingre Huoxue recipe,all of the two groups were treated for 2 months.To observe the cflinical effect and the change of cytokines and hemorrheology of the two groups.  Results:①The total efficiency of the observation group was 92.31%, the total efficiency of the control group was 70.49%,the difference was statistically significant (P<0.05); ②After treatment, the levels of IL-2、INF-γ were significantly increased and IL-10、IL-6 were significantly decreased with before,and the difference of the two groups was statistically significant (P<0.05);③After treatment, the whole blood viscosity and plasma viscosity of the observation group were decreased (P<0.05) with before, and that was lower than the control group (P<0.05).  Conclusion:Yangyin Qingre Huoxue recipe can improve the clinical efficacy of RAU, which may be related to regulation of immune function, improve hemorrheology.  
      关键词:aphthous ulcer;Yangyin Qingre Huoxue recipe;cytokines;Hemorheology   
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    • YANG Yi-wen
      Vol. 50, Issue 2, Pages: 62-63(2016)
      摘要:Objective:To observe the clinical efficacy of “Qutan Qingwei Decoction” in the treatment of simple obesity of damp-heat accumulation. MethodsEighty subjects were randomized into two groups:control group in which 40 were given dietary control and exercise therapy, and observation group in which 40 cases were given “Qutan Qingwei Decoction” as well as dietary control and exercise therapy, with a course of 12 weeks. The clinical efficacy, body weight and fat rate, and the levels of triglyceride (TG), total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) were observed.  Results:The overall effective rate was 30.0% in the control group and 80.0% in the observation group, with better efficacy in the observation group than in the control group(P<0.05). After treatment, the body weight and fat rate were reduced in both group (P<0.05), with more significant reduction in the observation group than in the control group (P<0.05). After treatment, in the observation group, the levels of TG and TC were decreased (P<0.05) and the level of HDL-C increased (P<0.05), with more significant improvement in the observation group than in the control group (P<0.05).  Conclusion:“Qutan Qingwei Decoction” is quite effective in the treatment of simple obesity and in improving blood lipids.  
      关键词:simple obesity;damp-heat accumulation;“Qutan Qingwei Decoction”;clinical observation   
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    • DAI Pu-ding,LI Wei-yi,DENG Jian-min,CHEN Zhe
      Vol. 50, Issue 2, Pages: 64-66(2016)
      摘要:This paper try to study the theory of the long needle therapy to guide clinical practice. In this paper, we discuss on the naming of the needle, operation method, efficacy, and clinical application, related research in modern days, typical cases and experiences. It is believed that there is satisfactory efficacy of the long needle therapy in treating some difficult and intractable diseases.  
      关键词:long needle therapy;long needle;elongated needle;acupuncture method   
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    • CHEN Xiao-meng,LIN Wu,CHEN Chun-tao,HUANG Shu
      Vol. 50, Issue 2, Pages: 67-68(2016)
      关键词:warm heart yang;skin diseases;clinical experience   
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    • LIU Chun-fang,CAO Hui-jie,CHENG Yan-mei,ZHANG Xiu-lian,ZHU Sheng-liang,WANG Hong-wei
      Vol. 50, Issue 2, Pages: 69-73(2016)
      摘要:Objective:To observe influence of the “Dingxiang Jiangqi Decoction” on IL-23/IL-17 inflammation axis in rats with reflux esophagitis. Methods40 Spregue-Dawley(SD) rats were randomly divided into treatment group,control group,model group and normal group, 10 in each group. Reflux esophagitis models were induced by cardiomyotomy and pylorus semiligation,and given the corresponding intervention measures. Pathological changes of esophagus tissues were observed by light microscope in each group, and the expression of IL-23,I L-17 mRNA in esophageal tissues of rats were detected by real-time RT-PCR, IL-17 protein content in esophageal tissues was measured by ELISA.  Results:Compared with the normal group, the esophageal mucosa in each group had different degrees of inflammation,but the Dingxiang Jiangqi Decoction group was mild than the western medicine group(P<0.05).The expressions of IL-23 and IL-17 mRNA and IL-17 protein in the esoph ageal tissues of model group were significantly higher than the normal group(P<0.05). Compared with model group, the expressions of IL-23 and IL-17 mRNA and IL-17 protein in the esoph ageal tissues of Chinese medicine group were lower(P<0.05), and the expression of IL-23mRNA in western medicine was lower(P<0.05). Compared with western medicine group, IL-17 protein decreased and IL-17 mRNA expression decreased(P<0.05). There was no significant difference of IL-17 protein expression between the Dingxiang Jiangqi Decoction group and the normal group(P>0.05). There was no significant difference in IL-23mRNA expression in Dingxiang Jiangqi Decoction group,control group and normal group(P>0.05); while there was no significant difference between the Dingxiang Jiangqi Decoction group and the western medicine group(P>0.05).  Conclusion:“Dingxiang Jiangqi Decoction” can effectively improve the esophageal mucosal inflammation of reflux esophagitis rats,the regulation of the IL-23/IL-17 inflammation axis may be one of the mechanisms of the “Dingxiang Jiangqi Decoction”.  
      关键词:reflux esophagitis;IL-23/IL-17 inflammation axis;IL-17 mRNA;IL-23 mRNA   
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    • ZHOU Yu-qi,ZHANG Ying-cheng,WEI Pin-kang,YE Min
      Vol. 50, Issue 2, Pages: 74-78(2016)
      摘要:Objective:To observe the effect of “Xiaotan Sanjie Recipe” on the cell cycle distribution of colorectal cancer cell line,and to study the possible mechanisms. MethodsThe original “Xiaotan Sanjie Recipe” aqueous solution was lyophilized, weighted and dissolved in cell culture and stored. HCT116 cells were treated with different concentrations of “Xiaotan Sanjie Recipe” for 72h,cell cycle distribution was detected by flow cytometry,the expression of proteins(cyclinA2,cyclinB1,CDK2 and CDK1)were detected by Western Blotting.  Results:After being treated by “Xiaotan Sanjie Recipe” for 72 h,the proportion of the cells in S phase was increased in 0.47 and 0.94 g/L group, the difference was significant compared with the controlled group(P<0.01); the proportion of the cells in G2 phase were increased in 0.47,0.94 and 1.88 g/L group,the difference was significant compared with the controlled group(P<0.01). After being treated by “Xiaotan Sanjie Recipe” for 72 h,the expressions of cyclinA2, CDK2 and CDK1 proteins were significantly decreased in 0.24,0.47,0.94 and 1.88 g/L group,the expression of cyclinB1 was significantly decreased in 0.47,0.94 and 1.88 g/L group,the difference was significant compared with the controlled group(P<0.01),the effect was concentration-dependent.  Conclusion:“Xiaotan Sanjie Recipe” has the ability to induce the S phase and G2 phase arrest of HCT116 cell line,its mechanism might be down-regulating the expression of cyclinA2,cyclinB1,CDK2 and CDK1 proteins.  
      关键词:colorectal cancer;“Xiaotan Sanjie Recipe”;cell cycle   
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    • XIAO Hai-juan,SUN Jue,XU Jian-hua,FAN Zhong-ze
      Vol. 50, Issue 2, Pages: 79-83(2016)
      摘要:Objective:To investigate the molecular mechanisms of resistance of traditional Chinese medicine Changwei Qing(CWQ)reversal of human colon cancer oxaliplatin. MethodsExtract CWQ containing serum,using MTT assay to detect CWQ reversal index(RI),using the comet assay to detect cell DNA damaged and detect cell apopotosis by flow cytometr in resistant cells.  Results:CWQ drug serum containing reversing HCT116/L-OHP resistant cells to L-OHP resistance reversal index(RI)was 2.63 times. The CWQ L-OHP group of resistant cells could promote DNA damage(P<0.001)and apoptosis(P<0.01).  Conclusion:CWQ can reversal drug resistance of human colon cancer to Platinum-based Chemotherapy,and it's mechanism may has relationship with promotion DNA damage and apoptosis occurred in cancer cells.  
      关键词:Changwei Qing;oxaliplatin;chemoresistance;colon cancer;apoptosis   
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    • ZHANG Qiu-hui,KUANG Ji-lin,LI Ping
      Vol. 50, Issue 2, Pages: 84-88(2016)
      摘要:Objective:Through exploring the influence of the traditional Chinese medicine “Penyan Fang” on the expression of transforming growth factor-pi (TGF-β1) and its transforming growth factor-β receptor Ⅱ (TβR Ⅱ) in the uterine tissue and ovarian tissue of the female rats with sequelae of pelvic inflammatory disease to probe the functional mechanism of the “Penyan Fang”. Methods124 SD female rats were treated as the subjects and were randomly extracted 10 female rats as the blank group, 10 female rats as the sham operation group. After making models successfully,rat models were randomly divided into model group for 15 rats,Fuke Qianjin Capsule group for 15 rats,Penyan Fang high, medium and low dose groups for every 15 rats. Observing the change of the uterus tissue morphology under HE dyeing,and using the immunohistochemical method to observe the expressions of TGF-β1 and TβR Ⅱ of the rats in all groups after drug intervention for 21days.  Results:Compared with the blank group and sham operation group, the expression of TGF-β1 and TβR Ⅱ in the uterine tissue and ovarian tissue of the female rats increased in model group, and there was significant difference between the groups(P<0.01). Compared with model group, Fuyan Fang different dose groups and Fuke Qianjin Capsule group could reduce the expression of TGF-β1 and TβR Ⅱ in the uterine tissue and ovarian tissue of the female rats with sequelae of pelvic inflammatory disease,the difference between them was significant(P<0.05,P<0.01), the effects of Penyan Fang high dose group were the best, and the effects was equal to Fuke Qianjin Capsule group.  Conclusion:Panyan Fang can treat sequelae of pelvic inflammatory disease may through decreasing the expression of TGF-β1 and TβR Ⅱ in the uterine tissue and ovarian tissue and elieving and diminishing local inflammation.  
      关键词:“Penyan Fang”;sequale of pelvic inflammatory disease;TGF-β;1;TβRⅡ   
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    • WEI Si-jie,YUAN Xiu-rong
      Vol. 50, Issue 2, Pages: 89-93(2016)
      摘要:Objective:To get a microscopic identification of scorpion and centipede in “Shaoyao Shujin Tablet”. MethodsWe determined identification characteristics of scorpion and centipede by consulting document. We used microscopic identification method to identify the scorpion and centipede in a single taste, mixing herbs and Chinese medicine.  Results:We succeeded in the microscopic identification for the scorpion and centipede in multiple batches, and initially identified bristles, body wall fragments as well as the unique tissues and organs of centipede as characteristics.  Conclusion:Integrated with variations and recognizations, debris of the gas pipeline in centipede and bristles in scorpion were selected as the main distinguishing features of mixing medicine. At the same time, the hair nest, tubercles and non-ossification of the scorpion body wall fragments were selected as auxiliary identifying characteristics in mixing medicine. This method provides a simple, fast and easy method of identifying for compound prescription of scorpion and centipede.  
      关键词:scorpion;centipede;“Shaoyao Shujin Tablet”;microscopic identification   
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      发布时间:2022-08-31
    • LIU Chun-liang,CHEN Hui,XIONG Yuan-chang
      Vol. 50, Issue 2, Pages: 94-96(2016)
      摘要:Wrist-ankle acupuncture used for analgesia has obtained the good curative effect. The clinical research of the wrist-ankle acupuncture in postoperative analgesia in recent years was summarized from the aspects of mechanism, postoperative analgesia and postoperative complications. Wrist-ankle acupuncture for postoperative analgesia postoperative can effectively reduce the adverse events, reducing the use of analgesic drugs, improve the analgesic effectiveness and patient satisfaction, but still needs regulatory and analgesic drugs in combination therapies synergies and other aspects further research and discussion.  
      关键词:wrist ankle needle;postoperative analgesia;review   
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    • ZHOU Qiu-qiu,REN Wei-ming,WANG Yan-hong,YANG Dan,WANG Guo-ming,LI Yue-ru
      Vol. 50, Issue 2, Pages: 97-100(2016)
      摘要:As main processing product of Radix Ginseng, different processing drugs method of red ginseng leads to different effect on the content of saponin, polysaccharide and AFG in red ginseng. There are unique ingredients in red ginseng which are different from fresh ginseng and dried raw ginseng, and such contents contain the pharmacological activity such as anti-diabetes, anti-tumor, anti-aging, anti-oxidation and anti-fatigue etc.  
      关键词:red ginseng;processing drugs;unique ingredients;pharmacological activity   
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