最新刊期
期 9 ， 2015
- 摘要：Objective:To observe the clinical curative effects of “Sanjie Tongluo Decoction” combined with radiotherapy on brain metastasis tumor from lung cancer Methods:76 patients with brain metastasis tumor from lung cancer were equally randomized to the therapy group and the control group. The patients in the therapy group were provided “Sanjie Tongluo Decoction” after radiotherapy, while the patients in the control group were provided radiotherapy and symptomatic treatment, which follow-up 6 months. The efficacy of the solid tumor, progress free survival, tumor markers and immune functions were evaluated between the two groups Results:① The evaluating effective rate was 94.74% and 89.47% respectively in the therapy group and the control group; There was no significant difference in clinical efficacy between the two groups (P>0.05). ② The progression free survival of brain metastases median was 5.67 months and 3.29 months respectively in the therapy group and the control group; There was significant difference in PFS in between the two groups (P<0.05). ③ Compared between the two groups after the treatment, the serum levels of CEA, CA50 and CA125 were significantly lower in the therapy group than in the control group(P<0.05). ④ Compared between the two groups after the treatment, the NK levels were significantly higher in the therapy group than in the control group(P<0.05) Conclusion:“Sanjie Tongluo Decoction” can inhibit tumor growth of brain metastases after radiotherapy, and can prolong the progression free survival, as well as can improve the immune functions of the patients.关键词：lung cancer;brain metastasis;“Sanjie Tongluo Decoction”;radiotherapy;progression free survival
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical effects and mechanism of “Qingli Huayu Xiaoshi Decoction” on pyelic stones Methods:80 cases of pyelic stones were randomly divided into treatment group and control group, and 40 patients in each group. Patients in treatment group were given “Qingli Huayu Xiaoshi Decoction”, while patients in control group were given Pai Shi Ke Li for 6 weeks. Treatment efficacy and levels of urinary calcium and uric acid were calculated and analyzed Results:Cure rate of treatment group was 87.5% and total effective rate was 95.0%; Cure rate of control group was 37.5% and total effective rate was 72.5%; compared with control group, treatment group achieved much higher cure rate(P<0.01). After treatment, urinary calcium and uric acid of treatment group decreased significantly (P<0.05,P<0.01), while urinary calcium of control group decreased after the treatment(P<0.05)；and urinary calcium and uric acid of treatment group were lower than control group(P<0.05) Conclusion:“Qingli Huayu Xiaoshi Decoction” could efficiently and safely move renal stone, and the mechanism was related to decreasing urine calcium level and urine uric acid level.关键词：“Qingli Huayu Xiaoshi Decoction”;pyelic stones;urinary calcium;uric acid
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发布时间：2022-08-31 - 摘要：Objective:To investigate the clinical therapeutic effect and function mechanism of “Baogen-Ⅰ Decoction ” on Repeated Respiratory Tract Infection(RRTI)(deficiency of both lung and spleen, DBLP) Methods:120 children with RRTI were assigned (DBLP) randomly into two groups, the test group treated with “Baogen-Ⅰ Decoction ” and the control group treated with Pidotimod Solution, and the course of the treatment was 8 weeks. The clinical efficacy and the cell group changes of T-cell subsets and immunoglobulin before and after treatment were observed Results:The effective rate of test group and control group were 91.67% and 66.67% respectively. The clinical therapeutic effect of test group was better than that of control group(P<0.01). After the treatment, IgG, IgA and IgM level increased than that before the treatment in both groups(P<0.05,P<0.01). IgG, IgA and IgM level increased more significantly in test group than the control one(P<0.01) ; the level of CD3+, CD4+and CD8+ of the test group after the treatment increased than that before the treatment, and the level of CD3+ and CD4+ increased more significantly in test group than the control group (P<0.01) Conclusion:“Baogen-Ⅰ Decoction” could well regulate the humoral immunity and cellular immunity of children with RRTI and has a better clinical efficacy in children RRTI (DBLP).关键词：“Baogen-Ⅰ Decoction ”;Repeated Respiratory Tract Infection(RRTI);immunoglobulin;T-cell subsets
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical effect of “Ningshen Mixture” treating postmenopausal women with abnormal blood lipids Methods:70 postmen-opausal women with abnormal blood lipids were randomly divided into treatment group and control group, 35 cases in each group. The treatment group was treated with “Ningshen Mixture” while control group was given by Simvastatin. Courses of the both groups were 2 months. Levels of blood lipid and sex hormones, dietary scores and BMI were observed Results:① 68 cases completed the test finally, which contained 34 cases of treatment group and 34 cases of control group. ② Intra-group comparison:All indexes had significant difference in both groups before and after treatment(P<0.05). Compared between the two groups after the treatment, there were significant differences of the levels of TC, LDL-C(P<0.05). ③ Compared between the two groups after the treatment, there were significant differences of the levels of E2 and T(P<0.05). ④ Compared between the two groups after the treatment, there were no obvious difference for dietary scores(P>0.05), but there were significant differences of the levels of BMI(P<0.05) Conclusion:The effect of treating postmenopausal women with abnormal blood lipids with “Ningshen Mixture” were satisfied, of which possible mechanism was to regulate sex hormones level in Vivo.关键词：dyslipidemia;postmenopause;“Ningshen Mixture”;sex hormones
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发布时间：2022-08-31 - 摘要：Objective:To evaluate Wuqinxi Exercise effect on mechanics characteristic of abdominal and back muscles and pain in patients with chronic nonspecific low back pain Methods:72 adults with chronic low back pain were randomly divided into treatment group and control group, 36 in each group. Patients in treatment group were treated with Wuqinxi Exercise while patients in control group were treated with conventional rehabilitation gymnastics. The courses of the two groups were 6 months. Scores of SF-MPQ , indexes of PT, PT/BW, AP, TW and F/E and IEMG were observed Results:① 63 patients completed the study in which 32 patients in treatment group and 31 patients in control group.② Compared between the two groups after the teratment, there was a significant difference in SF-MPQ total score , PRI and PPI (P<0.05). ③ Compared in each group before the treatement, there was significant difference in back and abdominal isokinetic testing (P<0.05), while there was no significant difference between the two groups after treatment. ④ Compared in each group after the treatement, there was significant difference in IEMG of left obliquus externus abdominis in 30°/s (P<0.05). ⑤ There was negatively correlated in low degree between level and socere of PT/BW in 30°/s Conclusion:Wuqinxi Exercise is a useful treatment for chronic low back pain in middle-aged people. It has more positive effect on relieve pain and improve health-related life quality that caused by chronic low back pain.关键词：nonspecific low back pain;aged and elderly people;Wuqinxi Exercise;rehabilitation gymnastics;Isokinetic Test;Surface EMG
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of minimally invasive stitch in the treatment of low and high simple anal fistula Methods:One hundred cases with low and high simple anal fistula were divided into test group and control group randomly, 50 cases ineach group. Test group was treated by minimally invasive stitch, and control group was treated with traditional low and high simple anal fistula otomy. Observe the clinical efficacy, healing time, postoperative pain, anus functions Results:The total effective rates were 100% in the two groups. The healing time, postoperative pain were reduced and anus functions was protected effectively by minimally invasive stitch in test group which better than control group, with remarkable difference between the two groups (P<0.05) Conclusion:Both treatments of minimally invasive stitch and anal fistula otomy are effective surgical method for anal fistula, but minimally invasive stitch has advantages including shorten the healing time, relieve postoperative pain and protect the anal function better.关键词：anal fistula;minimally invasive stitch;anal fistula otomy;clinical efficacy
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发布时间：2022-08-31 -
Clinical study of catheter drainage combined with loose thread-drawing in treating high anal fistula
摘要：Objective:To observe the clinical effect of catheter drainage combined with loose thread-drawing on high anal fistula Methods:68 cases of high anal fistula patients were randomly divided into treatment group and control group, 34 cases in each group. Patients in treatment group were treated with catheter drainage combined with loose thread-drawing; patients in control group were treated with inferior incision combined with tight thread-drawing. The curative rate, wound healing time, recurrence rate, postoperative pain, anorectal pressure changes to evaluate anal function were compared between the two groups Results:The cure rate of treatment group and control group were 94.12% and 82.35% respectively, the treatment group was higher than control group (P<0.05); in wound healing time, the treatment group was shorter than the control group (P<0.05); in postoperative pain after surgery 7 days and 10 days, the treatment group pain score was less than the control group (P<0.05) Conclusion:Catheter drainage combined with loose thread-drawing on high anal fistula can be increased on the cure rate and reduce postoperative pain on the basis of the effective protection of anal function.关键词：high anal fistula;catheter drainage;loose thread-drawing;anal function- 5
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发布时间：2022-08-31 - 摘要：Professor Chen Xiang-jun thinks that the basic pathogenesis of Sjogren’s syndrome lies in qi-yin deficiency as the root cause and dryness-fire and stasis-toxin as the branch cause; and the therapeutic principle concentrates on enriching yin and moistening dryness. The specifi Methods: include producing body fluids to moisten dryness by sweat cold herbs, nourishing liver and kidney by salty cold herbs, replenishing spleen-qi to generate body fluids, supplementing yin fluids by acid sweat herbs, enriching and activating blood to produce body fluids, and purging fire to save stomach yin.关键词：Sjogren’s syndrome;experience of famous doctor;Chen Xiangjun
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发布时间：2022-08-31 - 摘要：This paper explores the key points of four diagnosti Methods:. Inspecting patients’ eyes is the most important way of diagnosing depression syndrome. Listening to the reflected ideas and dispositions of patients’ words in the auscultation and olfaction is needed. Integration of auscultation and olfaction as well as inquiry should be built on the basic of trust between doctor and patient, we can pay more attention on the etiology of patients’ emotional hurts, past history, and natural endowment from the elementary to the profound. Palpation mainly refers to physical examination. Based on the four diagnosti Methods: of TCM, we also need to combine with the laboratory tests, related scales, and other examinations to make a comprehensive analysis and judgment.关键词：depression syndrome;diagnostic methods;four diagnostic methods
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发布时间：2022-08-31 - 摘要：This article tries to make a brief overview on the research and clinical application of Xuanfu medicine theory from the concept,function and essence of Xuanfu,the closed pathology and open treatment of Xuanfu and the practical meaning of Xuanfu theory by collecting ancient books and modern articles. Xuanfu medicine theory is a unique part of traditional Chinese medicine. Xuanfu medicine theory makes our understanding of the structure of body according to the T.C.M theory to a deeper level and plays a significant role in the guiding the diagnosis of many miscellaneous diseases in clinical practice.关键词：Xuanfu;function and characteristic;clinical significance
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发布时间：2022-08-31 - 摘要：Objective:To discusses the possible link between ovarian blood flow parameters of patients with polycystic ovary syndrome and TCM syndrome,which aims at providing a scientific basis for the syndrome differentiation of traditional Chinese medicine treatment of this disease Methods:There were 178 patients in this experiment with polycystic ovary syndrome diagnostic criteria of western medicine and can be classified into kidney deficiency type, phlegmy wet block type and qi stagnancy and blood stasis type on the criteria of Chinese medicine. Ovarian resistance index and pulse index were tested with method of ultrasonic measuring and the differences of different TCM syndrome were analyzed Results:There was significant difference in ovarian resistance index and pulse index between the three TCM syndromes(P<0.05), and the indexes of kidney deficiency type and phlegmy wet block type were higher than that of qi stagnancy and blood stasis type; there was no statistical significance between kidney deficiency type and phlegmy wet block type(P>0.05) Conclusion:There were certain relationships between ovarian blood flow parameters (ovarian resistance index and pulse index) of patients with polycystic ovary syndrome and TCM syndrome which can provide a scientific basis for the syndrome differentiation of traditional Chinese medicine treatment of this disease.关键词：polycystic ovary syndrome;TCM syndrome;ovary;ovarian blood flow parameters
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发布时间：2022-08-31 - 关键词：coronary heart disease;atrial fibrillation;angina pectoris;palpitation;teaching ward round
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发布时间：2022-08-31 - 摘要：This paper aims at introducing Professor Tang Hanjun’s experience on treating Hashimoto’s Thyroiditis. It is believed that pathogenesis of this disease are stagnancy of the liver and function deficiency of the spleen, stagnation of qi and sputum. Health supporting and goiter clearing therapy is the treating principle of this disease. The therapy can classified into 2 aspects:the fundamental solution is replenishing qi to invigorate the spleen and relieving the depressed liver, the temporary solution is eliminating goiter and dissipating phlegm, eliminating phlegm and softening indurated mass. 3 proven cases were provided.关键词：Hashimoto’s thyroiditis;“Fuzheng Qingying Decoction”;experience of famous doctors;Tang Hanjun
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发布时间：2022-08-31 - 摘要：This paper discusses Wang Yiqin’s experience on treating children asthma. It is believed that pathogenesis of this disease are congenital deficiencies and the imbalance of lung, spleen and kidney.Treatment period included attack stage and remission stage.Treatment therapy included taking Chinese medicine orally,herbal paste point application.关键词：children asthma;“Shegan Mahuang Decoction”;“Xiao Pingchuan Fomula”;“Guti Tongqiao Fomula”;experience of famous doctror;Wang Yiqin
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发布时间：2022-08-31 - 摘要：This paper did a discussion on the experience of Chen Zhiwei on syndrome differentiation and treatment of condensing ostitis. It is believed that deficiency of liver and kidney as well as exopathgen is the main pathogeneses of this disease. The treatment of this disease include nourishing liver and kidney, dispelling dampness and heart, expelling coldness and dredging tendon, activate blood circulation and smoothing collaterals, and medicine should be fitted respectively.关键词：condensing ostitis;TCM therapy;experience of famous doctors;Chen Zhiwei
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发布时间：2022-08-31 - 摘要：This paper aims at introducing Director Jiang Zhiyan’s experience in treating childhood recurrent respiratory tract infection by stages. It is considered that heat, phlegm and blood stasis is the key of the pathogenesis of childhood recurrent respiratory tract infection; at the cute phase is the evidence of positive syndrome of heat, phlegm and blood stasis, and at steady period is the imbalance of the lung and spleen. Regulating lung and collateral is the first choice of treatment in cute phase, and reinforcing lung and spleen is the first choice in steady period, and treated by “Qingfei Tongluo decoction”. Typical drug pairs and a proven case are presented.关键词：childhood recurrent respiratory tract infection;“Qingfei Tongluo decoction”;differentiating and treating by stage;Jiang Zhiyan
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发布时间：2022-08-31 - 摘要：This paper provided 4 proven cases of Shi Yinyu’s during the period of study instructed by Professor Shi Yinyu. The 4 proven cases embody Professor Shi’s experience on treating traumatology diseases with classical prescriptions as well as the concept of wholism, consideration both of qi and blood and integration of the internal and the external.关键词：traumatology;classical prescriptions;experience of famous doctor;Shi Yinyu
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发布时间：2022-08-31 - 摘要：This paper aims at discussing Characteristics of Zhang Xichun’s Yixuezhongzhongcanxilu on treating warm disease. Zhang Xichun had unique insights on warm disease and had his special features on treating warm disease. He proposed that warm disease could be classed into three aspects. Mr Zhang obey the theory of Liqi on treating pestilence and had his special prescription, making new prescription for disease of Fuqi according to the theory of Neijing, presenting fresh ideas on Baifutang syndrome differentiation. Zhang Xichun made a great contribution on development and perfection of war disease theory because of his academic thoughts and clinical experience.关键词：Zhang Xichun;Yixue Zhongzhong Zanxilu;warm disease
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发布时间：2022-08-31 - 摘要：This paper aims discussing the academic thoughts of manicdepressive disease due to phlegm and blood stasis interaction in history though reviewing TCM literature. Characteristics of onset, pathogenesis, symptom and law of differentiation and treating were analyzed in this paper which can lay basis of literature and theory for treating schizophrenia by TCM.关键词：manicdepressive disease;phlegm and blood stasis interaction;literature review
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发布时间：2022-08-31 - 关键词：ovarian hyperstimulation syndrome;Guzhang Syndrome;Enforcing Spleen and Nourishing Kidney;experience of famous doctor;Li Xiangyun
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发布时间：2022-08-31 - 摘要：This paper introduced the application of treating menopausal syndrome with modified “Cassia Twig and Dragon Bone Combination”. It is believed that the pathogenesis of this disease is the imbalance of Yin and Yang, and “Cassia Twig and Dragon Bone Combination” can balance Yin and Yang. A proven case was attached.关键词：menopausal syndrome;imbalance of Yin and Yang;“Cassia Twig and Dragon Bone Combination”
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发布时间：2022-08-31 - 摘要：Objective:To explore the effect of “Bushen Jianpi Decoction” on tumor recurrence inhibition of high metastasis models of human hepatocellular carcinoma (HCC) after curative in nude mice and its synergies and toxicity-reducing effect on Sorafenib Methods:Decorticate and reset the tumor in HCCLM3 model nude mice with a size of 1 mm×1 mm×1 mm. Transplant the tumor into the liver of experimental nude mice orthotopicly. On postoperative day 15,do laparotomy to resct the new tumor. Divide experimental nude mice into group A,B,C and D,6 in each group. From the 3rd day of the 2nd surgery,according to the nude mice weight,they received gavage in a dosage of 0.1ml/10 g each day,for 4 weeks in all. Group A were given “Bushen Jianpi Decoction”. Group B received Sorafenib suspension. Group C were treated with both two medicines. Group D were administered 0.9%NS. Record the weight of nude mice pre-dose,the 7th,14th,21st and 28th day(D0,7, 14,1, 28)of the course as well as the fodder consumption every day of each group. After treatment,the tumor weight and size were measured and Blood Routine Index(eg.WBC,RBC,Hb,PLT) were tested Results:① Tumor weight and size:In Group A,B and C,Tumor weight(P<0.001) were lower and size(p=0.001) smaller than in Group D; Both weight and size in Group C decreased more than Group A(P<0.05). ② Mice weight:Compared Group A with Group B,C,D, there was statistical difference(P<0.05). Mice weight on D7、14、21、28 were all lower than D0(P<0.05).Falling range from smaller to larger was Group A(0.60±1.75),C(1.29±1.63),D(1.57±1.84)and B(2.14±2.40). ③ Fodder consumption:Compared Group A with Group B,C,D, there was statistical difference(P<0.001)；Group C and D had statistical difference(P<0.05). Group A ate more than the other groups while Group C’s fodder consumption first slowly raised then decreased. Fodder consumption of Group B and D reduced more obviously. ④ Blood Routine Index(WBC, RBC, HGB, PLT):Four indexes of Group A and D had no statistical difference(P>0.05),but WBC,RBC and HGB count of Group A were higher than D. Compared Group A with Group B and C,there were statistical difference(P<0.05). Group B was the lowest of all indexes(P<0.05). Group C was a little bit more than B,while Group B and C had no statistical difference(P>0.05) Conclusion:“Bushen Jianpi Decoction” could inhibit recurrent tumor growth,improve the body resistance against Sorafenib,decrease its toxic reaction to the Blood System,and stablize the body dietary and weight. The Decoction could restrain HCC recurrence after hepatectomy,and it had synergies and toxicity-reducing effect on Sorafenib.关键词：“Bushen Jianpi Decoction”;after operation on hepatectomy;tumor recurrence;tumor inhibition;Sorafenib;synergies and toxicity-reducing
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发布时间：2022-08-31 - 摘要：Objective:The aim of this study is to investigate the effect of “Danzhi Jiangtang Capsule” on PI3K/AKT signaling pathway in the liver of diabetic rats Methods:55 male SD rats were fed with high calorie diet except the normal control group for 4 weeks. A single intraperitoneal injection of streptozotocin (STZ) of 35mg/kg,when the diabetic rodent model was build, the rats were randomly re-divided into 4 groups:model group, high-does group of DJC, low-does group of DJC and pioglitazone group. High-does group of DJC and low-does group of DJC were treated with 1.08 g/(kg·d) and 0.54 g/(kg·d) repectively, pioglitazone group was treated with 10mg/(kg·d), the blank group and the model group were treated with the same volume of saline .Continuous intragastric administration for 8 weeks,took the liver,detected β-actin, PI3K/AKT in liver tissue of rats by reverse transcription reaction and Quantitative Real-time PCR. Total RNA was extracted from the liver tissue of rats with Trizol kit,determinated the blood glucose and blood lipid Results:Expression of PI3K/AKT in model group increased significantly ,DJC evidently inhibited the excessive expression of PI3K/AKT and RNA. Compared with the normal control group (P<0.05 or P<0.01); the blood glucose of rats were increased significantly (P<0.01) compared with. After being given “Danzhi Jiangtang Capsule ” for 8 weeks,the level of glucose was decreased(P<0.01) ,curative effect was similar to Pioglitazone. The blood glucose and the PI3K/AKT correlation analysis showed a significant positive correlation Conclusion:The DJC has a significant intervention effect on the over expression of PI3K/AKT signaling pathway in the liver of diabetic rats,this may be related to the protection of the liver,reduced vascular endothelial inflammatory reaction.关键词：“Danzhi Jiangtang Capsule”;PI3K/AKT;diabetes;rat
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发布时间：2022-08-31 - 摘要：Objective:To investigate the protective effects and the possible mechanisms of velvet antler polypeptides (VAP) on microwave radiation-induced injury to the development of secondary follicles in mouse ovaries Methods:Adult female mice were radiated by microwave with 5 mW/cm2 intensity for 30 days. After that,the radiated mice were injected intraperitoneally with VAP (1.5 mg·kg-1·d-1,3 mg·kg-1·d-1 and 6 mg·kg-1·d-1) for 30 days. The development of secondary follicles in mouse ovaries was observed. The apoptosis of granulosa cells in secondary follilces was detected by TUNEL assay. The immunohistochemistry technique was used to analyze the expression of anti-apoptosis protein Bcl-2 and active pro-apoptosis protein caspase-3 in granulosa cells from secondary follilces. The content of estrogen in mouse serum was detected by ELISA Results:Compared with model group,VAP with high concentration significantly improved the development of secondary follicles and histological structure. In high VAP treatment group,the apoptosis of granulosa cells and the expression of active pro-apoptosis protein caspase-3 in granulosa cells from secondary follilces were greatly decreased,while the expression of anti-apoptosis protein Bcl-2 in granulosa cells from secondary follilces and the estrogen level in mouse serum were significantly increased Conclusion:Thes Results: suggest that VAP with high concentration can significantly improve the development of impaired secondary follicles induced by microwave radiation in mice; and its mechanism may be associated with reducing the granulosa cell apoptosis in secondary follicles and promoting the synthesis and secretion of estrogen.关键词：velvet antler polypeptides;microwave radiation;ovary;apoptosis;secondary follicle
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发布时间：2022-08-31 - 摘要：Objective:To explore the mechanism of tonify kidney and drain dampness method in the treatment of gouty arthritis, therefore, to provide the theory basis for the prevention and treatment of tonify kidney and drain dampness method of gouty arthritis Methods:Eighty four rats were randomly divided into seven groups:blank control group,model group,herbal control group,western medicine control group,high dosage herbal group,medium dosage herbal group and low dosage herbal group,twelve rats in each group.The uric acid sodium and oxygen polybenzoxazines potassium were used to induce rat acute gouty arthritis model. HE staining method was used to observe the pathological changes of synovial tissue. ELISA was used to detect the concentration of serum IL-6 and TGF-β in rats and analyze the data Results:Compared with the blank control group, levels of IL-6 and TGF-β in serum in each model groups significantly increased (P<0.05). Compared with model group, the concentration of serum IL-6 in high dosage herbal group and medium dosage herbal group decreased significantly(P<0.05), while the concentration of serum TGF-β increased (P<0.05), with no difference in colchicine group (P>0. 05). Compared with the model group, the concentration of serum IL-6 in herbal control group and low dosage herbal group decreased (P<0.05), but there were still differences compared with colchicine group (P<0.05). However, colchicine group and low dosage herbal group TGF-β concentration compared with the model group, no significant difference (P>0. 05) Conclusion:Tonify kidney and drain dampness method can inhibit the expression of IL-6 in rat acute gouty arthritis, promote the expression of TGF-β, so it has an effect on the prevention and treatment of gouty arthritis.关键词：tonify kidney and drain dampness method;gouty arthritis;IL-6;TGF-β
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发布时间：2022-08-31 - 摘要：Objective:To study the acute toxicity of “Kushen Gel” on single dose in rats Methods:Twenty female SD rats were randomized into observation group and control group(10 rats in each group), and respectively given “Kushen Gel” and matrix via vagina, twice a day for one day. In the following 14 days, the general conditions, body weight, amount of foot intake and body temperature of the rats in the two groups were observed; and such organs as vagina were observed on the fifteenth day Results:The general conditions of the two groups were normal; the body weight, amount of foot intake and body temperature of the rats in the two groups were of no difference(P>0.05); no abnormal changes were found in internal organs Conclusion:Intravaginal administration of “Kushen Gel” is safe.关键词：“Kushen Gel”;medication on single dose;acute toxicity experiment;intravaginal administration;rat
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发布时间：2022-08-31 - 摘要：This paper reviewed the progress in G0/G1 phase、S phase and G2/M phase about traditional Chinese medicine regulating blood tumor cell cycle in the following application research in recent years. It is believed that Blood tumor and abnormal regulation of hematopoietic cell cycle mechanism are closely related,traditional Chinese medicine and its effective extract can arrest cell cycle in a limited point,thus inhibiting tumor cell proliferation,inducing apoptosis,and this is the important pathogenesis of haemal tumour.关键词：blood tumor;cell cycle;traditional Chinese medicine
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发布时间：2022-08-31 - 摘要：This paper did a review on the research progress of phellinus polysaccharides anti-tumor mechanisms. It is believed that phellinus polysaccharides anti-tumor mechanisms can be manifested into three aspects: immune regulation, anti-angiogenesis and antioxidation. It is shown that phellinus polysaccharides combined with cyclophosphamide could enhance effect and minus side effects.
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发布时间：2022-08-31
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