最新刊期
期 8 ， 2015
- 摘要：Objective:To observe the effect of treating on shoulder-hand syndrome after stroke under superficial acupuncture combined manipulation Methods:60 cases of the patient with shoulder-hand syndrome after stroke were randomly divided into treatment group and control group equally. Both of the two groups were treated with usual rehabilitation therapy, and control group was treated with manipulation therapy while treatment group was treated with superficial acupuncture on the base of control group. The courses of the two groups were 6 weeks. Cores of upper limb FMA function and pain VAS were observed Results:① There were significant difference in FMA scores in each group before and after the treatment (P<0.05); there were significant difference in FMA scores between the two groups after the treatment (P<0.05). ② There were significant difference in pain SVAS scores in each group before and after the first treatment (P<0.05); after the treatment, there were significant difference in pain VAS scores between the two groups (P<0.05). After that, VAS scores in the two groups increased, but after 24 hours, VAS pain score of the treatment group was significantly lower than that of the control group (P<0.05). ③ Before and after the overall treatment, there were statistically difference in pain VAS scores in each group (P<0.05); before and after the treatment, there were statistically difference in pain VAS scores between the two groups (P<0.05) Conclusion:The shoulder-hand syndrome after stroke treated b Methods: of superficial acupuncture combined manipulation can significantly alleviate limb pain and improve their motor functions.关键词：shoulder-hand syndrome;stroke;superficial acupuncture;manipulation
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发布时间：2022-08-31 -
Clinical evaluation of “Chinese Medicine Therapy for Community Cerebral Infarction in Convalescence”
摘要：Objective:To evaluate the clinical efficacy of “Community Cerebral Infarction in Convalescence treated with the therapy of TCM” Methods:Sixty-four cases of community cerebral infarction in convalescence were randomly divided in to observation group (31 cases) and control group (33 cases). Cases in the control group were treated with the usual treatment of western medicine while cases in the observation group were treated with “Community Cerebral Infarction in Convalescence treated with the therapy of TCM” (Chinese medicine, acupuncture or point sticking)on the base of the usual treatment. The course of the two groups was 1 year. BI, scores of modified Rankin scale and NIHSS scale were observed Results:Before and after the treatment, there were significant difference in BI, modified Rankin scale and NIHSS scale in each group(P<0.05); before and after the treatment, there were significant differences in BI, modified Rankin scale and NIHSS scale between the two groups(P<0.05) Conclusion:The “Community Cerebral Infarction in Convalescence treated with the therapy of TCM” can improve the neurological defects in ischemic stroke,and improve quality of life.- 5
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发布时间：2022-08-31 - 摘要：Objective:To observe the effects of “Zilongjin Tablets” on the quality of life in patients with locally advanced non-small cell lung cancer(NSCLC) Methods:Seventy-eight subjects were randomized into treatment group and control group(39 cases in each group), and treated respectively by “Zilongjin Tablets” and placebo, with a course of two months. The scores of clinical symptoms and quality of life were evaluated before and after treatment Results:After treatment, in the treatment group the scores of such symptoms as fatigue were deceased in comparison with before treatment(P<0.05), with lower scores in the treatment than in the control group(P<0.05); the scores of quality of life such as somatic function were improved after treatment in the treatment group(P<0.05), with more significant improvement in the treatment than in the control group(P<0.05) Conclusion:Maintenance treatment with “Zilongjin Tablets” can improve the clinical symptoms and quality of life in non-small cell lung cancer.关键词：“Zilongjin Tablet”;advanced non-small cell lung cancer;Chinese medical syndrome;quality of life
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of Adhesive Intestinal Obstruction(AIO) with electroacupuncture and Chinese Medicine Nasal Feeding and Enema Methods:All the 60 patients suffered with AIO were randomized into two groups.30 patients in the treatment group were treated with basic surgical treatment in combination with electroacupuncture and chinese medicine nasal feeding and enema,the other 60 patients in the control group were treated with only basic surgical treatment. The data including clinical efficacy, the restoration of gastrointestinal function, operability were compared between two groups Results:The total effective rates were 86.7% in study group, and 73.3% in control group,with significant difference in two groups (P<0.05). The restoration of gastrointestinal function and the remission time of clinical symptoms and signs of study group was better than control group,there were significantly different (P<0.05). In study group 4 cases have been transferred to surgery, and 11 cases in control group,with significant difference in two groups(P<0.05) Conclusion:The electroacupuncture and chinese medicine nasal feeding and enema in the treatment of AIO promote faster recovery of gastrointestinal function, and improve the clinical efficacy.关键词：adhesive Intestinal Obstruction(AIO);electroacupuncture;herbal nasal feeding;herbal enema;gastrointestinal function
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发布时间：2022-08-31 - 摘要：Objective:To observe the therapeutic effect of “Haizao Muli Xiaoying Decoction” combined with western medicine on the treatment for hyperthyroidism Methods:164 patients with hyperthyroidism were randomly divided into treatment group and control group equally. The control group was treated with methimazole, and the treatment group was treated with “Haizao Muli Xiaoying Decoction” based on the control group. The course of the two groups was 3 months. The therapeutic effect and adverse reaction were observed, and the recurrence of 1 year follow-up was observed, at the same time, syndrome score, levels of thyroid hormone (TT3, TT4, FT3, FT4 and TSH) were compared Results:① 80 cases had completed in the test.② The total effective rate of the treatment group and control group was 95.00% and 82.50% respectively; there was statistically difference of the clinical efficacy between the two groups (P<0.05).③ After the treatment, there was statistically difference in TCM syndrome score, levels of TT3, TT4, FT3, FT4 and TSH (P<0.05). ④ There were statistically difference in recurrence rate between the two groups (P<0.05). ⑤ There was no significant difference between the two groups in adverse reaction (P<0.05) Conclusion:“Haizao Muli Xiaoying Decoction” combined with western medicine on the treatment of hyperthyroidism can relief syndrome, regulating the levels of thyroid hormone, and can significantly reduce the recurrence rate.
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发布时间：2022-08-31 - 摘要：Objective:To observe clinical therapeutic effect of syndrome differentiation combined with acupuncture in treating elderly sensorineural tinnitus Methods:100 cases of elderly sensorineural tinnitus were randomly divided into treatment group and control group,50 cases in each group.The medication group was treated with Flunarizine tablets, and the treatment group was treated with syndrome differentiation combined with acupuncture. The course of each group was 6 weeks. The clinical effect was observed, and tinnitus score, hearing threshold, tinnitus loudness were investigated Results:①The total effective rates of the treatment group and control group was 92.00% and 78.00% respectively, with a significant difference in the effects between the two groups (P<0.05); ② Before and after the treatment, there was significant difference in tinnitus volumes in each group(P<0.05); before and after the treatment, there was significant difference in tinnitus volumes between the two groups (P<0.05). ③ There was a hearing impairment in tinnitus patients with 2K hz and 4K hz stimulating in each group before and after the treatment, and there was significant difference in hearing threshold (P<0.05); After the treatment, there was significant difference in hearing threshold between the two groups, and hearing impairment in treatment was shot than control group (P<0.05). ④ After the treatment, there was significant difference in tinnitus loudness between the two groups(P<0.05); before and after the treatment, there was significant difference in tinnitus loudness between the two groups(P<0.05 Conclusion:syndrome differentiation combined with acupuncture in treating elderly sensorineural tinnitus can alleviateing tinnitus remarkably.关键词：sensorineural tinnitus;elderly;syndrome differentiation combined with acupuncture;acupuncture;hearing threshold;tinnitus loudness
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发布时间：2022-08-31 - 摘要：Objective:To observe the therapeutic effect of manipulation on temporomandibular disorders,and the range of temporomandibular joints’ motion on imageology Methods:60 patients are randomly divided into a manipulation group (Group A) and a semiconductor laser group (Group B) with 30 cases in each one then observe through therapeutic effects, Fricton’s Craniomandibular Index and the range of temporomandibular joints’motion Results:The total effective rate is 93.3% in Group A and 70.0% Group B. The therapeutic effect of Group A is better than Group B (P<0.05). Both Groups’ Fricton’s Craniomandibular Index numbers are lower after treatment (P<0.05), and Group A is lower than Group B (P<0.05). Both Groups’ range distance increase after treatment (P<0.05), and Group A is longer than Group B (P<0.05) Conclusion:Manipulation can improve the clinical symptoms of temporomandibular disorder and the function of temporomandibular joints.关键词：Temporomandibular Disorder;Manipulation;Range of Motion
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of “Bushen Huatan Recipe” in treating polycystic ovary syndrome (PCOS) Methods:62 subjects were randomized into treatment group (30 cases) and control group (32 cases). The control group was treated with Diane-35 orally while the treatment group was treated with “Bushen Huatan Recipe”. The courses of the two groups were 3 menstrual cycles. The clinical effects and adverse reaction were observed, the reproductive endocrinological indicators (T, FSH, LH, E2, PRL, P) and the ovarian volume were compared before and after treatment Results:① The overall effective rate was 96.7% in the treatment group and 75.00% in the control group,with a difference between the two groups (P<0.05).② Before and after the treatment in each group,there were significant difference in the levels of T (P<0.05); After the treatment in each group, there were significant difference in T level and the ovarian volume (P<0.05); After stop using medicines for 3 months, the levels of T and the volume of ovary in treatment group was better than that in control group(P<0.05). ③ After treatment,there were significant differences in LH levels in both groups (P<0.05) ; There was significant difference in LH level between the two groups. ④ There was significant difference in adverse reaction between the two groups(P<0.05) Conclusion:“Bushen Huatan Recipe” can improve and stabilize clinical symptoms, regulate reproductive endocrine hormone level in PCOS with hyperandrogenism and make patients recover ovulation and promote menstrual bleeding. There was little adverse reaction in the treatment with “Bushen Huatan recipe”.关键词：polycystic ovary syndrome (PCOS);hyperandrogenism;“Bushen Huatan Recipe”;Diane-35;ovarian volume
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficiency of low-frequency electro-acupuncture in the treatment of knee osteoarthritis Methods:Eighty subjects were randomized into treatment group and control group (40 cases in each group), and treated respectively by low-frequency electro-acupuncture and Diclofenac Sodium Sustained Release Capsules, with a course of 28 days. The visual analogue scale(VAS) and the Lysholm knee scoring scale(LKSS) were used to observe the knee pain severity and function of knee joints Results:After treatment, the VAS scores in both groups were significantly lowered(P<0.01), with lower scores in the treatment group than in the control group(P<0.05); the LKSS was increased in the treatment group after treatment(P<0.01), with high score in the treatment group than in the control group(P<0.05) Conclusion:Low-frequency electro-acupuncture is effective to relieve pain and improve joint function in knee osteoarthritis.关键词：electro-acupuncture therapy;low frequency;knee osteoarthritis
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发布时间：2022-08-31 - 摘要：This paper introduces the application of the idea of “Treating lung and spleen simultaneously” of treating Children Recurrent Respiratory Tract Infection (RRTI) in different period. We discuss the therapeuti Methods: of Dong’s Traditional Chinese Pediatrics in protecting the spleen and stomach function, including “Supi decoction”,acupuncturing ‘Sifeng’ acupoint, Meridian pilot, diet adjustment, and herbal extracts. At the same time, we introduce the relevant researches about the idea of ‘Treating lung and spleen simultaneously’ in children RRTI.关键词：“Treating lung and spleen simultaneously”;children recurrent respiratory tract infection;Supi decoction;Sifeng acupoint;meridian pilot
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发布时间：2022-08-31 - 摘要：This paper introduces Xu Xiaopu’s academic experiences of treating pediatric cough. It is argued that pediatric cough can be divided into due to exopathy or due to internal injury. The principal therapy on treating exogenous cough of children is moistening lung and removing phlegm and therapeutic principle on treating pediatric cough that induced by internal injury was staring from lung and spleen. The typical medical records were represented in this paper.关键词：pediatric cough;simultaneous treatment of spleen and stomache;famous doctor’s experience;Xu Xiaopu
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发布时间：2022-08-31 - 摘要：This paper discusses the depression syndrome with various forms,including single depression syndrome as well as the coexistence of diseases and depression syndrome,diseases induced by depression syndrome and depression syndrome induced by diseases,dominant depression syndrome and recessive depression syndrome,restricted depression syndrome and general depression syndrome. Single depression syndrome is a kind of emotional diseases with disorder of function. The coexistence of diseases and depression syndrome which means there are depression paralleling organic diseases and TCM diseases,and it can be divided into two parts,that is diseases induced by depression syndrome and depression syndrome induced by diseases. Dominant depression syndrome is induced by the seven outside emotions,which can be differentiated easily in clinics. Recessive depression syndrome is induced by the seven inside emotions in clinics,and the patients might be also specially gifted in the field of recessive depression syndrome. Restricted depression syndrome is a simple dominant depression syndrome induced by bad emotions and stagnation of qi,such as hysteria,lily disease,globus hystericus,and insomnia. General depression syndrome includes the coexistence of diseases and depression syndrome,depression syndrome induced by diseases,recessive depression syndrome,and all of the diseases related by bad emotions. Discussing the morphology of depression syndrome aims to meet the needs of TCM clinical diagnosis and treatment better.关键词：depression syndrome;morphology;the coexistence of diseases and depression syndrome;dominant depression syndrome;recessive depression syndrome;restricted depression syndrome;general depression syndrome
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发布时间：2022-08-31 - 摘要：The logical and realistic possibility of integrated traditional Chinese and western medicine was analyzed by philosophical principles. It is view that the fundamental reason for different theory system is due to differences in the standard and way of division of the world. A theoretical system formally accepted is usually marked by establishment of its own ontology language system. This paper adopted the intuitive concept of set to interpret the logical possibility of integrated traditional Chinese and western medicine, and found that it is realistically impossible to produce the ontology language system belonging to integrated traditional Chinese and western medicine. The identity of integrated traditional Chinese and western medicine at last depends on what kind of standard of measure we used. Based on the above theoretical review,we also analyzed the major factors influencing the future development of traditional Chinese medicine,integrated traditional Chinese and western medicine.关键词：integrated traditional Chinese and western medicine;ontology;language
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发布时间：2022-08-31 - 摘要：Objective:To investigate the occurrence and TCM syndrome characteristics of hearing impairment in patients with type 2 diabetes Methods:100 hospitalized patients with type 2 diabetes were examined both ears by pure tone hearing test and classified with syndrome differentiation. Hearing impairment detection rate, damage degree and distribution of TCM syndrome were investigated Results:① Hearing impairment detection rate was 53.0%, and 79.25% of patients were with mild hearing loss,severe hearing damage were not found. The average age and damage degree of hearing impairment are higher than the normal people(P<0.05) . Hearing impairment detection rate of patients ≥60 years was 72.3%. ② 81.8% type 2 diabetic patients with Liver and Kidney deficiency syndrome in this study occurred hearing impairment Conclusion:Patients with type 2 diabetes are more likely to develop hearing impairment. The major TCM syndrome of hearing impaired patients with type 2 diabetes is Liver and Kidney deficiency.关键词：type 2 diabetes;hearing impairment;TCM syndrome
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发布时间：2022-08-31 - 关键词：hypokalemia;consumptive disease;teaching ward round
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发布时间：2022-08-31 - 关键词：postoperative mammary carcinoma;“Wushi Xiaoliu Powder”;clinical experiences;Wu Kun-lun
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发布时间：2022-08-31 - 摘要：This article summarizes chief physician Jin Changjuan’s clinical experience of syndrome differentiation and treatment of diarrhea after operation on esophagus cancer. Doctor Jin advocates to start from spleen, liver and kidney to treat diarrhea and the therapeutic principle include enforcing spleen and nourishing kidney, regulating liver, resolving dampness and inducing astringency, and activating blood as an adjuvant therapy.关键词：esophagus cancer;diarrhea after operation;TCM therapy;clinical experience;Jin Changjuan
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发布时间：2022-08-31 - 关键词：stranguria;urinary tract infection;classical prescription
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发布时间：2022-08-31 - 摘要：This article summarizes Wang Xixin’s academic thoughts in four aspects by th Methods: of literature research. These thoughts include locating acupoints with standard method and selecting acupoints with moderate degree, selecting acupoints correctly and pay attention to syndrome differentiation, rescuing patients in danger with acupuncture combined with herbs, from abundance to limitation and making great contribution to incoming generation.关键词：Handbook of Acupuncture;Wang Xixin;academic thoughts
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发布时间：2022-08-31 - 摘要：This paper provide a proven case of “Warm Yang and Induce Diuresis” on differentiating and treating thymoma with large pericardial effusion and pleural effusion. It is believed that pericardial effusion is due to phlegmatic hygrosis and weakness of vital qi, so strengthening spleen and warm yang is the main therapy to strengthen body resistance, and purgation and promoting qi and removing blood stasis is the main therapy to eliminating the pathogenic factor. It is important to combine strengthening body resistance with eliminating the pathogenic factor and it is necessary to adopt the treatment both manifestation and root cause.关键词：pericardial effusion;thymoma;TCM therapy;proven case
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发布时间：2022-08-31 - 关键词：Herba Taraxaci;clearing and diverging fire of liver and stomach;clearing dampness and dredging meridians and collaterals;clinical experience
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发布时间：2022-08-31 - 摘要：Objective:To study the effects of cryptotanshinone on the antibody level of rats with the positive Anticardiolipin antibody and antiβ2-glycoprotein and the expression of TLR4/NF-κB Signaling Pathway Methods:The female SD rats were divided randomly into cryptotanshinone(0.03 μg/g)group, Salvia miltiorrhiza injection(6 μl/g)group, aspirin(0.04 μg/g)group, hydrosolvent(tween-80 saline at the same liquid volume) group, model group(normal saline at the same liquid volume) and blank group(NS at the same liquid volume). Fed the rats by gavage with medicine continuously from the first day for 2 weeks. ACA and Anti-β2-GP1 levels were tested with the method of ELISA after the model was set up and fed by gavage, and then put the male and female rats into the same cage. The rats were sacrificed on the 12th day after pregnancy, serum level of TNF-α and the number of live births were detected by the method of ELISA. Decidual tissue were selected, and the expression of the TLR4 protein were tested by the method of SP Results:① Cryptotanshinone may effectively reduce the concentrations of ACA, Anti-β2-GP1 and can increase the rate of live births effectively. ②The protein expression of TLR4 in decidual cells can be reduced by cryptotanshinone which resulting in lower TNF-α concentration to decrease the risk of miscarriage Conclusion:Cryptotanshinone has a protective effect on low pregnancy of rats with the positive of Anticardiolipin antibody and anti-β2-GP1, which is partially via attenuating inflammatory through TLR4 / NF-κB signaling pathway.关键词：cryptotanshinone;anticardiolipin antibody;anti-β;2;-glycoprotein 1;TLR4/NF-κB signaling pathway;recurrent spontaneous abortion
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发布时间：2022-08-31 - 摘要：Objective:To study the impact of “Jieyu Yubao Prescription” on estrous cycle, β-EP and pinopodes in chronic stress rats and discuss the regulatory mechanism of “Jieyu Yubao Prescription” on endometrial receptivity in chronic stress rats Methods:80 SPF SD rats were randomly divided into 5 groups:normal control group, model group, “Jieyu Yubao Prescription” low-dose group, “Jieyu Yubao Prescription” middle-dose group, “Jieyu Yubao Prescription” high-dose group. Except the normal group, the remaining four groups of rats were established drug chronic stress model. From the 15th day of stimulation, the rats in the “Jieyu Yubao Prescription” middle-dose group were given the solution of “Jieyu Yubao Prescription”, intragastric administration capacity was 11.2 μl/g；normal group and model group were fed with an equal volume of purified water (11.2 μl/g); low-dose group and high-dose group were given 1/2 and 2 times of middle-dose group once a day, the administration capacity was 5.6 μl/g and 22.4 μl/g. The estrous cycle of rats was observed from the fourteenth day after model-building. All the rats in the five groups were made to copulate (female∶male=2∶1) 16∶00 on the 28th day of stimulation. On the 4th day after confirmation of pregnancy by Vaginal smears, the rats were killed at 16∶00 at the day of drug withdrawal. Serum β-EP was tested and endometrial VEGF levels was observed by Transmission Electron Microscope. Pregnancy rate and the average of implantation number were calculated Results:① The general situation and estrous cycle:hair of the rats in the normal group, middle-dose group and high-dose group were clean and neat, active and with bright eyes and normal diet, body weights increased rapidly. Compared with model group, the time of estrous cycle of the rats increased obviously (P<0.05), and there was no significant difference compared with normal group(P>0.05).② The serum β-EP content:Compared with normal group, the serum β-EP of model group and low-dose group was significantly increased (P<0.05); compared with model group, the serum β-EP of middle-dose group and high-dose group was significantly decreased (P<0.05); the serum β-EP of middle-dose group and high-dose group was obviously lower that that in the low-dose group (P<0.05). ③ The expression of endometrial VEGF levels:compared with model group, the score of model group and low-dose group decreased obviously(P<0.05); there was no significant difference in score of high-dose group compared with normal group(P>0.05); the score of middle-dose group and high-dose group obviously higher than the normal group(P<0.05); the score of middle-dose group and high-dose group obviously higher than the low-dose group(P<0.05). ④ Compared with normal group, the average of implantation number of rats in model group and low-dose group decreased significantly (P<0.05), while there was no significant difference in middle-dose group and high-dose group (P>0.05). Compared with normal group, the average of implantation number of rats in middle-dose group and high-dose group increased significantly (P<0.05). The average of implantation number of rats in middle-dose group and high-dose group was higher than that of low-dose group (P<0.05); there was no significant difference in middle-dose group and high-dose group (P>0.05) Conclusion:① “Jieyu Yubao Prescription” can improve or reduce chronic stress serum β-EP valuation effectively, and can reduce stress damage to the body, increase the body’s anti-stress ability, and shows a dose-dependent manner. ② “Jieyu Yubao Prescription” high-dose can significantly increase chronic stress in rats VEGF expression in the endometrium. ③ “Jieyu Yubao Prescription” can increase the expression of VEGF by balancing distribution of β-EP of the body due to the tension caused by the stress, and improve endometrial pinopodes maturity of endometrial epithelial cells, thereby improving the endometrial receptivity.关键词：“Jieyu Yubao Prescription”;chronic stress;endometrial;receptivity
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发布时间：2022-08-31 - 摘要：Objective:To clarify the Ginkgolide B-rapamycin drug-eluting stent system in the acceleration of early phase re-endothelialization and anticoagulation of porcine coronary artery Methods:9 pigs were used in this experiment,and 3 pigs were used in each kind of model (venous shunt model, high load thrombosis model,balloon injury model),and each pig was put separately in different stent (GB-RAP stent,RAP stent and bare metal stent). GB-RAP stent’s anti thrombosis effect was clarified through the arteriovenous shunt thrombosis model and high load GB-RAP model, the effect of early GB-RAP stent was observed through 1 weeks of porcine coronary artery balloon injury model Results:GB-RAP drug eluting stents has better antithrombotic effect in arteriovenous shunt model and high load thrombosis model than RAP stent and bare metal stent, and it was showed that GB-RAP drug eluting stents has good effect of re-endothel in 1 week after balloon injury in porcine animal model Conclusion:GB-RAP stent has good compatibility with biological scaffolds, and can accelerate the early phase re-endothelialization and improve the anticoagulation property.关键词：drug-elution stent;Ginkgolide B;endothelialization;thrombus
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发布时间：2022-08-31 - 摘要：Objective:To study “Fuxin Decotion” on the expression of PI3K-Akt-GSK3β pathway in cardiac failure rats with cardiac muscle hypertrophy induced by adriamycin, and to study the action mechanism of “Fuxin Decotion” on the effect of the cardiac muscle in heart failure Methods:75 healthy adult male Wistar rats were randomly divided into blank group, model group, captopril group, “Fuxin Decotion” low-dose group, “Fuxin Decotion” high-dose group. Each group except blank group was treated respectively after modeling with adriamycin. Expression and quantitative analysis of PI3K, Akt and GSK3β of myocardial were detected b Methods: of immunohistochemistry and Western blotting respectively after 4 weeks Results:PI3K, Akt positive expression area in model group was the highest, captopril group, “Fuxin Decotion” low-dose group and “Fuxin Decotion” high-dose group was lower, and the blank group was the lowest; the GSK3β protein expression in the blank control group was the highest compared with captopril group, “Fuxin Decotion” low-dose group and “Fuxin Decotion” high-dose group Conclusion:“Fuxin Decotion” in treating heart failure is related to PI3K-Akt-GSK3β pathway.关键词：“Fuxin Decotion”;heart failure;PI3K;Akt;GSK3β
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发布时间：2022-08-31 - 摘要：Objective:To study the effect of “Yiqi Qinghua Decoction” on intestinal flora in HFD-induced non-alcoholic fatty liver disease rats model Methods:30 adult clean healthy Wistar rats was selected and randomly divided into blank group,model group and treatment group, 10 in each group. Rats in model group and treatment group were fed with high fat diet to prepare for non-alcoholic fatty liver disease rats model, the treatment group were treated with “Yiqi Qinghua Decoction” at the same time in the first day while model group were treated with 0.9% NaCl solution with the same quantity. Rats in blank group were treated with general diet and 0.9% NaCl solution with the same quantity. The course of each group was 8 weeks. At the end of the experiment,liver function and LPS of rats were tested, liver were collected for observing pathological changing with method of HE staining. Intestinal flora were determined with the method of ERIC-PCR fingerprint,and a cluster analysis on the fingerprint was performed. Result ① The serum ALT,AST, TG, TC and LPS levels in model group were significantly increased than that in the blank group(P<0.05), and the level of ALT, AST and LPS in the treatment group were significantly lower than that in the model group(P<0.05). ② There were a little fatty infiltration in the liver cells of the treatment group and inflammatory cells and necrosis of hepatic cells were significantly reduced in the treatment group than that in the model group. ③ The composition and distribution of bands of ERIC-PCR fingerprint in the treatment group was more and wider than that in the model group which showed that the structure of intestinal flora of the rats in the treatment group was partially recovered under the intervention of “Yiqi Qinghua Decoction”. ④ It was showed that the similarity of intestinal flora in the blank group and treatment group was greater than that of the blank and model groups and of the model and treatment groups. The data above showed that “Yiqi Qinghua Decoction” can correct the disorder of intestinal flora of non-alcoholic fatty liver disease rats. The analysis of intestinal flora diversity of rats showed that the diversity of blank group and treatment group were higher than that of model group, and it showed that “Yiqi Qinghua Decoction” can increase the species of intestinal flora of non-alcoholic fatty liver disease rats and then to improve the disorder of intestinal flora of non-alcoholic fatty liver disease rats Conclusion:“Yiqi Qinghua Decoction” can effectively alleviate injury of liver cells and improve steatosis on non-alcoholic fatty liver disease rats,and also can the disorder of intestinal flora of non-alcoholic fatty liver disease rats.关键词：non-alcoholic fatty liver disease;rats;intestinal flora;“Yiqi Qinghua Decoction”
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发布时间：2022-08-31 - 摘要：Objective:To study the extraction technology of Qinling Polyporus triterpenoids, and carries on the identified research for its comprehensive utilization Methods:The content of polyporus total triterpenes was measured by UV spectrophotometry with vanillin-glacial acetic acid solution and perchloric acid as developing agent; With ethanol as solvent, using the method of solvent extraction of triterpenoid compounds. The optimum extraction is evaluated by single factor test and orthogonal test, and the structure of the triterpenoids was identified based on the physicochemical constants and spectral evidences Results:The most optimum conditions for this extraction was adding six times amount of 95% alcohol and refluxing three times,2h once Conclusion:The extraction process is simple, feasible, and can provide a scientific basis for the study of Qinling Polyporus.关键词：Qinling polyporus;triterpenoids;extraction process;identification
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发布时间：2022-08-31 - 摘要：Based on the review of related literature,this article summarized the research progress of the active ingredients of acetylcholinesterase inhibitors from botanical drugs,medicinal animals,Fungus medicine and the screenin Methods: in recent years,in order to develop new ideas of anti-Alzheimer’s research on the basis of Chinese herbs.关键词：acetylcholinesterase inhibitors;Alzheimer disease;Chinese herbs;review
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发布时间：2022-08-31 - 摘要：This article summarized the research progress of pharmacological actions and clinical applications of Rhizoma Bletillae in recent years. It is argued that the pharmacological actions of Rhizoma Bletillae includes anti-bacteria, promoting blood circulation and arresting bleeding, promoting wound healing and the restoration of gastrointestinal mucosa damage, promoting hemopoietic ability of marrow, antitumor, caries prevention and repairing of the alveolar bone defect, etc. The clinical applications of Rhizoma Bletillae includes the treatment of tuberculous, gastrointestinal hemorrhage, ulcer, trauma, dermatosis, blood disease, tumor, pharyngitis, oral ulcer and dental caries, etc.关键词：Rhizoma Bletillae;pharmacological action;clinical application;review
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发布时间：2022-08-31
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