最新刊期
期 6 ， 2015
- 摘要：This paper introduces the clinical experience of Professor Men Cheng-fu of treating threatened abortion by using modified Shoutaiwan. It is argued that the kidney deficiency, blood deficiency was the basic pathogenesis of this disease, and syndrome of yin deficiency, blood heat and fluid deficiency often appeared in the disease. Modified Shoutaiwan was the basic remedy in treating this disease based on syndrome differentiation which was divided into kidney deficiency type and yin deficiency with blood heat type. A verification case is attached.
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发布时间：2022-08-31 - 摘要：This paper is to discuss the clinical decision making of TCM treatment for primary liver cancer. It is believed that the combination of disease and syndrome differentiation is the basic principle of the treating, and the treatment is based on the clinical stage. Stress should be put on strengthening the body resistance in the early stage while eliminating pathogens is as subsidiary role. In the medium term stress should be put on eliminating pathogens and strengthening the body resistance is as subsidiary role. In the advanced stage, equal importance should be put on strengthening the body resistance and eliminating pathogens and external treatment should be used to alleviate sufferings at the end stage.关键词：primary liver cancer;TCM treatment;clinical decision making
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发布时间：2022-08-31 - 摘要：Objective:This paper is to investigate the traditional Chinese medicine(TCM) syndrome characteristics of mild cognitive impairment in the elderly in community with cross-sectional method Methods:Eligible participants are the residents aged 55 years and over in the 24 villages in the 5 streets(towns) in Pudong District in Shanghai. The survey is to investigate the prevalence of mild cognitive impairment in the elderly, TCM physique, and classification of TCM syndrome Results:①There are 6 400 samples in this survey and in which 4 086 samples (88.83%) are completed, and 612 samples(14.98%) are mild cognitive impairment patients. ②There are more female patients (70.92%) than the male patients (29.08%) in the 612 samples ( P<0.05). There are more aged 70 and more (51.47%) than the aged 69 and below (48.53%) (P<0.05). In the 612 samples, there are 88.56% with education time less than 8 years and 11.44% equal and more than 8 years (P<0.05). ③There are 261 patients with biased physique patients of Normal constitution (42.65%), 351 patients with biased physique (57.40%). Most patients with biased physique belong to phlegm-dampness constitution, yang-insufficiency constitution and qi-asthenia constitution, and the least patients with biased physique belong to damp-heat constitution and allergic constitution. ④According to the classification of TCM syndrome, there are 26.11% spleen and kidney deficiency type , 20.63% hyperactivity of yang due to yin deficiency type and 10.74% qi-blood deficiency type respectively Conclusion:Most patients of mild cognitive impairment in the elderly belong to phlegm-dampness constitution, yang-insufficiency constitution and qi-asthenia constitution, and there are more spleen and kidney deficiency type, hyperactivity of yang due to yin deficiency type and qi-blood deficiency type according to the classification of TCM syndrome. Mild cognitive impairment featured of deficient root with overdo superficial, manifest as deficient of spleen, kidney and qi-blood, and overdo of dampness and Qi-stagnation.关键词：mild cognitive impairment;symptomatology;physique;the syndrome differentiation
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发布时间：2022-08-31 - 关键词：upper digestive tract ulcer;upper gastrointestinal bleeding;teaching ward-round
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发布时间：2022-08-31 - 摘要：This paper summarizes professor Tong Xiaolin’s clinical experience of using Gegen (Lobet Kudzuvine Root). Professor Tong is good at using Gegen in treating headache, ankylodeire, diabetes and diarrhea by the method of Gegen’s nature of stimulating qi and elevating yang. Professor Tong’s experience has clinical significance.关键词：Gegen;relaxing muscles and joints;elevating yang;clinical experience;Tong Xiaolin
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发布时间：2022-08-31 - 摘要：This article discusses the clinical experience of Professor Wang Peng in treating bronchial asthma in view of collateral theory. It is believed that pathogenesis of bronchial asthma includes Yang collateral deficiency, pathogen congealing and lung collaterals stasis, Qi regurgitating. Dredging collaterals and lowering the adverse Qi is used to treat the disease. Acrid drugs are the essential medicines, make good use of insect drugs.关键词：bronchial asthma;collateral disease;clinical experience;Wang Peng
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发布时间：2022-08-31 - 摘要：This paper introduces medical records of Professor Qi Cong’s experience in treating gynecological diseases by Leech. Professor Qi Cong thought that the main symptom of gynecological disease is blood stasis as a result of deficiency,and activating blood circulation and dissipating blood stasis is the general method in treating gynecological diseases. Professor Qi is good at treating gynecological diseases such as oviduct blocking, polycystic ovarian syndrome, endometriosis, hysteromyoma, etc.关键词：Gynecological diseases;activating blood circulation and dissipating blood stasis;leech;experience of famous experts in TCM;Qi Cong
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发布时间：2022-08-31 - 摘要：This paper introduces Professor Chen Hongfeng’s clinical experience with acne breast carbuncle. It is believed that the case of the disease includes the congenital defects, emotional suppression, etc, which can be divided into nipple discharge stage, breast mass stage, maturity stage and fistula stage in the process of the differentiating and treating of the disease. Internal therapy was the preterred alternative if there was no ulceration and external therapy was used if there was serious ulceration. 2 pieces of proven cases were presented in this paper.关键词：acne breast carbuncle;therapy of TCM;clinical experience;Chen Hongfeng
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发布时间：2022-08-31 - 摘要：This paper introduces the experience of treating kidney disease with the treatment of classical prescription. The evolution of kidney disease in view of six channel syndrome differentiation includes taiyang disease, shaoyang disease, shaoyin disease, accompanied with fluid retention syndrome and blood stasis through the period of the evolution. The direction of application and corresponding formula are provided in this paper.关键词：chronic kidney disease;six channel syndrome differentiation;classical prescription
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发布时间：2022-08-31 - 摘要：This article summarizes the application, usage, etiology, pathogenesis, symptoms, and disease classification of medicine wine by Zhang Zhongjing, discusses its influences, and poses some questions.关键词：medicine wine;method of application;law of application;formula discussion
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发布时间：2022-08-31 - 关键词：cholestatic jaundice;therapy of TCM;experience of famous doctor;MA Guitong
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发布时间：2022-08-31 - 摘要：Objective:This paper is to evaluate the clinical effect on Yin-Yang-balancing point-to-point acupuncture in patients with post-stroke hemiparalysis according to the paralysis stage, so as to provide effective solutions for clinical treatment Methods:307 patients from 7 research centers randomly divided into A group (104 patients), B group (102 patients) and C group(101 patients). Patients in group A were treated with Yin-Yang-balancing point-to-point acupuncture combined with rehabilitation training, patients in group B were treated with Yin-Yang-balancing point-to-point acupuncture, Patients in group C were treated with rehabilitation training, and the course of treatment in each group was 28 days. Clinical neurological deficit scores (NDS), functional comprehensive assessment scale (FCA), motor status score(FMA) were observed Results:① 93 samples were completed in group A, 90 samples were completed in group B and 85 samples were completed in group C after the test. During the 2 months follow-up, 89 samples were got in group A, 88 samples were got in group B and 80 samples were got in group C. ② In full analysis set, the total effective rate in the 3 groups is 77.45%, 71.57% and 62.64% respectively. The difference between each group was statistically significant (P<0.05). Group A and B compared with group C respectively, the difference was statistically significant(P<0.05). In the completed follow-up set, the total effective rate in the 3 groups is 85.39%, 84.09% and 75.00% respectively, and the difference between each group was statistically significant (P<0.05). Group A and B compared with group C respectively, the difference was statistically significant(P<0.05). ③ After the treatment of 14 days, 28 days and during the 60 days follow-up, the difference between NDS and base line in each group was statistically significant(P<0.05). The change values of NDS of group A and B were significantly better than group C(P<0.05). ④ After the treatment of 7 days, 14 days and during the 60 days follow-up, the respectively change values of NDS, FCA and the difference of base line was statistically significant(P<0.05). The change values of FCA, FMA of group A and B were significantly better than group C(P<0.05) Conclusion:Yin-Yang-balancing point-to-point acupuncture can improve stroke patients’ comprehensive rehabilitation level, neurological function, limbs motor function. The therapy combined with acupuncture and rehabilitation benefits for stroke patients mostly.
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发布时间：2022-08-31 - 摘要：Objective:This paper is to observe the clinical effect of the treatment with “Yiqi Huoxue Huatan Decoction” on senile patients of low extremity atherosclerotic disease(LEAD) of asymptomatic period Methods:70 cases of aged patients with asymptomatic LEAD were randomly divided into treatment group and control group, and there are 35cases in each group. The control group was given Simvastatin and the treatment group was added using of “Yiqi Huoxue Huatan Decoctionin” on the basis of the control group. The course of treatment of the both groups was 12 weeks. The changes of clinical symptoms, ABI and IMT were observed during the course Results:①Compared before and after the treatment, the difference of clinical symptoms of TCM in both groups were statistically significant (P<0.05);compared after treatment of the two groups, the D-value of clinical symptoms of TCM were statistically significant(P<0.05). ②Compared before and after treatment, the difference in the level of ABI and the thickness of IMT were statistically significant (P<0.05); compared after treatment between the two groups, the D-value of level of ABI and thickness of IMT was statistically(P<0.05) Conclusion:The treatment of the early intervention period of asymptomatic atherosclerosis of the lower extremities by “Yiqi Huoxue Huatan Decoction” can significantly improved vascular elasticity and polish up Lower limb function of patients, and can delay the progress of LEAD.关键词：Lower extremity atherosclerotic disease;asymptomatic period;“Yiqi Huoxue Huatan Decoction”;ankle brachial index;femoral artery intima-media thickness.
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发布时间：2022-08-31 - 摘要：Objective:This paper is to observe the clinical curative effect of helicobacter pylori correlation gastritis treated by “Buqi Tuodu Xiaoyong Decoction” Methods:80 cases of patients with Helicobacter Pylori correlation gastritis were randomly divided into treatment group and control group, and there were 40 cases in each group. The control group treated with standard triple therapy; meanwhile treatment group was given “Buqi Tuodu Xiaoyong Decoction” based on the treatment in control group. The treatment course of the two groups was 14 days with follow-up 6 months. The clinical efficacy, adverse reaction, the change of clinical symptoms, Hp clearance and recurrence were observed during the course Results:① The overall effective rate was 95.00% in the treatment group and 77.50% in the control group, with a difference between the two groups(P<0.05).② Compared before and after the treatment, the difference of the clinical symptoms of TCM in both groups were statistically significant(P<0.05); compared after the treatment of the two groups, the difference of the clinical symptoms of TCM in both groups were statistically significant(P<0.05).③ Hp clearance of the treatment group was 90.00% and 72.50% in the control group, with a difference between the two groups(P<0.05).④ During the follow-up period, there were 2 cases of recurrence(5.56%) in the treatment group and 6 cases (20.69%) in the control group, with a difference between the two groups(P<0.05). ⑤No significant difference was found in adverse reaction between the two groups (P>0.05) Conclusion:Helicobacter Pylori correlation gastritis treated by “Buqi Tuodu Xiaoyong Decoction” combined with triple therapy can get high Hp clearance and low recurrence.关键词：Helicobacter Pylori;chronic gastritis;“Buqi Tuodu Xiaoyong Decoction”;triple therapy;recurrence
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发布时间：2022-08-31 - 摘要：Objective:To observe the response and tolerance of “Xiaoyu Jiangzhi Capsule” on healthy subjects to explore a safe effective dosage Methods:Randomized, multi-dose and open research was conducted. ①Twenty-four healthy subjects were randomized into six groups by single dosage respectively at 250 mg, 500 mg, 1 000 mg, 1 250 mg, and 1 500 mg; ②Ten healthy subjects were randomized into two groups by accumulative dosage at 1 250 mg and 1 500 mg, twice a day for total 7 days. Some indexes indicating liver and kidney functions were checked before and after administration of “Xiaoyu Jiangzhi Capsule”, and the adverse events were also recorded Results:The indexes indicating liver and kidney functions before and after treatment were at normal ranges, and no adverse events were found during the whole experiment Conclusion:“Xiaoyu Jiangzhi Capsule” is safe in clinical application at its recommended dosage.关键词：“Xiaoyu Jiangzhi Capsule”;phase I clinical trial;herbal dosage;tolerance;safety
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发布时间：2022-08-31 - 摘要：To observe the clinical efficacy of “Xiakucao Fluid” in the treatment of nodular goiter of qi depression and phlegm obstruction Methods:Sixty-six subjects were randomized into two groups:control group in which 33 cases were treated by Levothyroxin Sodium Tablets, and treatment group in which 33 cases were treated by Levothyroxin Sodium Tablets and “Xiakucao Fluid”, with a course of six months. The clinical efficacy, thyroid nodes and thyroid functions were observed Results:The total effective rate was 84.85% in the treatment group and 51.52% in the control group, with better efficacy in the treatment group than in the control group(P<0.01). After treatment, the maximal diameters of thyroid nodes were reduced in both groups(P<0.05, P<0.01), with smaller diameter in the treatment group than in the control group(P<0.01); the number of thyroid nodes was decreased in the treatment group(P<0.05), with fewer number in the treatment group than in the control group(P<0.05). The levels of FT3, FT4 and TSH changed little between before and after treatment, and the two groups(P>0.05) Conclusion:“Xiakucao Fluid” is quite effective against nodular goiter of qi depression and phlegm obstruction.关键词：nodular goiter;qi depression and phlegm obstruction;“Xiakucao Fluid”;thyroid function
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发布时间：2022-08-31 - 摘要：Objective:This paper is to determine the treatment efficacy of “Fuzheng Huashi Tonglin Decoction” (FZHSTL) on the recurrent urinary tract infection (UTI) in elderly women Methods:70 elderly women with recurrent UTI were randomized into treatment group and control group, 35 in each group. Subjects in both groups received standard antibiotic therapy. In addition, subjects in the control group received Bilinqing capsule while subjects in the treatment group received FZHSTL. The duration of the therapy was 6 months with a 3-month follow-up in both groups. The clinical efficacy, scores of TCM syndrome, and recurrence of UTI were assessed Results:① 4 subjects dropped off in the treatment group and 6 in the control group. 60 subjects had completed the study. ②The overall effective rate was 90.32% in the treatment group and 68.97% in the control. A significant difference was observed between two groups (P<0.05). ③ Compared before and after the treatment ,the difference of clinical symptoms of TCM in both groups were statistically significant (P<0.01); In addition, the changes of scores of TCM syndrome before and after treatment were different between the two groups (P<0.01). ④ During the follow-up, the rate of UTI recurrence was significantly lower in the treatment group than the control groups (P<0.05) Conclusion:FZHSTL combined with antibiotic therapy provides better clinical efficacy and reduces the incidence of recurrent UTI in elderly women.关键词：rinary tract infection;recurrent;elderly women;“Fuzheng Huashi Tonglin Decoction”;recurrence;antibiotic
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发布时间：2022-08-31 - 摘要：Objective:This paper is to observe the curative effect of “Qingdai Guben Soup” combined with metronidazole in treating atrophic vaginitis with syndrome of yin deficiency and dampness-heat Methods:60 patients diagnosed as atrophic vaginitis with yin deficiency and dampness-heat syndrome were randomly divided into treatment group and control group,30 in each group. The treatment group was given “Qingdai Guben Soup” and metronidazole, and control group was given metronidazole. The treatment course was 14 days. The clinical effect of the two groups, TCM symptoms, Vaginal cleaning degree and health score were observed. The recurrence rate of two the two groups in the following 3 months were compared Results:① After treatment, the total effective rate of the treatment group was 96.67%, while the control group was 83.33%, A significant difference was observed between two groups (P<0.05). ②Compared before and after the treatment, the difference of clinical symptoms of TCM in both groups were statistically significant (P<0.05); In addition, the changes of scores of TCM syndrome before and after treatment were different between the two groups (P<0.05).③Compared before and after the treatment, there was significant difference in the vaginal cleanliness and vaginal health score in each group(P<0.05); Compared before and after the treatment, there was significant difference in the vaginal cleanliness and vaginal health score between the two groups(P<0.05) ④ There was significant difference in the recurrence rate in the follow-up period between the two groups (P<0.05) Conclusion:“Qingdai Guben Soup” combined with metronidazole has curative effect on atrophic vaginitis with yin deficiency and dampness-heat syndrome.关键词：atrophic vaginitis;yin deficiency and dampness-heat;“Qingdai Guben Soup”;metronidazole;TCM-WM therapy
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发布时间：2022-08-31 - 摘要：Objective:The paper is to observe the clinical curative effect of Luo’s gynecological treatment of fallopian tube obstructive disease Methods:82 cases of oviduct obstructive infertility were randomly divided into the treatment group (42 cases) and control group (40 cases). The control group was treated by traditional Chinese medicine Luo’s Sundarbans decoction, while the treatment group treated with traditional Chinese medicine treatment of abdominal acupuncture on the basis of post iontophoresis (Luo’s external use prescription of traditional Chinese Medicine). Both of the group were 1 year for a course, clinical efficacy and the pregnancy rate were observed, and 1 year follow-up to observe the pregnancy Results:①The clinical total effective rate were 90.48% and 72.50% of the treatment group and the control group respectively, and the cure rate was 83.33% and 62.50% respectively. Comparison of the clinical efficacy between the two groups, the difference was statistically significant(P<0.05).②During the test, there were 27 cases of pregnancy in the treatment group, and 17 cases of pregnancy in the control group, the difference was statistically significant of the pregnancy rate between the groups(P<0.05).③Two patients were followed up for pregnancy rate showed no significant difference(P>0.05) Conclusion:Luo’s treatment of oral drug combined with external treatment on tubal obstruction disease is effective , the treatment can improve the pregnancy rate.关键词：obstruction of fallopian tube;infertility;internal and external treatment of traditional Chinese Medicine;abdominal applicator;Luo’s Sundarbans Decoction;phlegm and blood stasis
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发布时间：2022-08-31 - 摘要：Objective:This paper is to observe the clinical efficacy of cooling blood, clearing heat and removing dampness formula in treating damp heat immersed type of eczema Methods:178 cases of damp heat immersed type of eczema patients randomly divided into treatment group and control group on average, the control group was treated with loratadine and the treatment group was treated with cooling blood, clearing heat and removing dampness formula, both of the treatment of course were 2 months. Clinical efficacy, itch degree and changes of TCM syndrome were observed Results:The clinical efficacy of the treatment group and control group was 88.8% and 71.9% respectively, the clinical efficacy of treatment group was better obviously than the control group(P<0.05). After the treatment, the itch degree accumulated point and TCM symptom accumulated point of the two groups decreased obviously(P<0.05), and the accumulated points of the treatment group was lower than the control group(P<0.05) Conclusion:Cooling blood, clearing heat and removing dampness formula has good effect in treating damp heat immersed type of eczema.关键词：eczema;dampness and heat syndrome;therapy of TCM;cooling blood, clearing heat and removing dampness formula
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of wrist-ankle acupuncture in the treatment of acute lumbar sprain Methods:One hundred eighty subjects were randomized into three groups:group A in which 60 cases were by wrist-ankle acupuncture, group B in which 60 cases were treated conventional body acupuncture, and group C in which 60 cases were treated by both wrist-ankle acupuncture and body acupuncture, with a course of three days Results:The cure rate was 78.3% in group A, 81.6% in group B and 98.3% in group C; the clinical efficacy was better in group C than in group A(P<0.01) and group B(P<0.05). After treatment, the VAS score for lumbago were markedly reduced in the three groups(P<0.01), with greater difference of VAS score between before and after treatment in the group C than in group A(P<0.01) and group B(P<0.05) Conclusion:Wrist-ankle acupuncture can help conventional body acupuncture in the treatment of acute lumbar sprain.关键词：acute lumbar sprain;wrist-ankle acupuncture;body acupuncture
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy and therapeutic mechanisms of “Quyu Qingbi Decoction” and arthroscopic operation in the treatment of knee osteoarthritis Methods:Eighty-seven subjects were randomized into observation group(n=43) and control group(n=44); all the patients were treated with arthroscopic operation and intra-articular injection of sodium hyaluronate, with a course of six weeks. The clinical efficacy, knee function and pain scores were evaluated, and the levels of such inflammatory factors in knee fluid as TNF-α, IL-1β, MMP-3 and MMP-13 were detected Results:①The total effective rate was 90.7% in the observation group and 72.7% in the control group, with better efficacy in the observation group than in the control group(P<0.05). ②After treatment, the knee functional scores were increased and the pain scores were reduced in both groups(P<0.05), with significant differences in the knee functional score and the pain score between the two groups(P<0.05). ③After treatment, the levels of TNF-α, IL-1β, MMP-3 and MMP-13 were reduced in both groups(P<0.05), with more significant reduction in the observation group than in the control group(P<0.05) Conclusion:“Quyu Qingbi Decoction” can regulate the inflammatory agents in knee osteoarthritis patients undergoing arthroscopic operation to improve knee functions.关键词：knee osteoarthritis;arthroscopic operation;“Quyu Qingbi Decoction”;fumigation therapy
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发布时间：2022-08-31 - 摘要：Objective:This paper is to evaluate the efficacy of electro acupuncture XiYan in treating knee osteoarthritis and the modern rehabilitation evaluation Methods:100 patients with knee osteoarthritis disease were divided randomly into two groups, the treatment group was treated with electro acupuncture for 4 weeks, and the control group was treated with topical diclofenac diethylamine dmulgel for 4 weeks, Lequesne and Vas score were recorded before and after the experiment. Subjects were assessed with isokinetic measurement Results:After two-week treatment, VAS and Lequesne score of the two groups were better than before(P<0.05), there was no significant difference between the two groups(P>0.05). After four-week treatment, VAS and Lequesne score of the two groups were better than before(P<0.01), as to the VAS score , there was no significant difference between two groups(P>0.05),but the Lequesne score of the treatment group was better than the control group(P<0.05). The rehabilitation value such as PT, PTWB, WF and APT was higher than four weeks before, and the treatment group was batter than the control group(P<0.05) Conclusion:Electro acupuncture XiYan had advantage in curing KOA, can improve quadriceps femoris muscle strength and improve the stability and the flexibility of the knee.关键词：knee osteoarthritis;electro acupuncture therapy;rehabilitation;isokinetic muscle strength
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发布时间：2022-08-31 - 摘要：Zhang Xichun thought that the efficacy and characteristic of centipede include calming internal wind, expelling exogenous wind, eliminating stagnant blood, abolishing poison, regulating neural, etc. According to his experience, there are significant efficacy in the clinical practice in treating optic neuropathy, facial paralysis, channel blocking, etc.关键词：Zhang Xichun;centipede;clinical experience
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发布时间：2022-08-31 - 摘要：The current paper adopts traditional and moder Methods: to screen 86 legume drugs which have rheumatic efficacy in Chinese Materia Medica, discusses their properties such as three characteristics, flavors, meridian, efficacy, indications. Most legumes rheumatism drugs are bitter in taste, warm in nature, channel tropism to spleen, lung, kidney and liver. Most are non-toxic. The main efficacy of legume drugs are dispelling wind and eliminating dampness, promoting blood circulation and detoxification, for the treatment of wind dampness arthralgia syndrome and bloodstasis syndrome.关键词：legumes;rheumatism;drug;law of drug properties
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发布时间：2022-08-31 - 摘要：Objective:This paper is to investigate the anti-depression effect of classic recipe “Ganmai Dazao Decoction” by observing the change of behavior characteristics in depressed rats Methods:40 Wistar male rats were randomly divided into control group,model group,“Ganmai Dazao Decoction” group and fluoxetine group,10 in each group. The models were established by chronic unpredictable stress combined solitary keeping 28 days and were given 28 days of drug intervention after modeling success. They were carried by open field test and sugar consumption test to observe the behavior change of depressed rats. The experimental data was recorded and statistical analysis Results:Compared with normal control group,Ganmai Dazao Decoction group and fluoxetine group,weight,horizontal movement distance, upright time and the consumption of sugar water in model group, Ganmai Dazao Decoction group and fluoxetine group showed a tendency to decrease significantly(P<0.05). After the 56th day of the test, weight, horizontal movement distance and the consumption of sugar water increased in the Ganmai Dazao Decoction group(P<0.05), while the fluoxetine group were increased than the model group(P<0.05). Compare between the Ganmai Dazao Decoction group and the fluoxetine group,no significant difference was found in the above index(P>0.05) Conclusion:“Ganmai Dazao Decoction” can affect behavioral characteristics in rat model of depression and relieve the depressed-like behavior in depressed rats.关键词：depression syndrome;disease model;rat;“Ganmai Dazao Decoction”;behavior characteristics
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发布时间：2022-08-31 - 摘要：Objective:This paper is to study antihypertensive effect of “Qianyang Decoction” in rats with hypertension by abdominal aortic banding Methods:Hypertention model was established by abdominal aortic banding,and a sham operation was performed for controls. Wistar rats were randomly divided into sham-operation group and operation group. After the modeling,operation rats were randomly divided into model group,perindopril group,“Qianyang Decoction” group,there were 10 rats in each group. 4 weeks after operation,rats were gavaged for 8 weeks. The blood pressure of rats was determined by measuring left forelimb blood pressure with caudal artery continuous dynamic measurement instrument Results:①4 weeks after the modeling,compared with the sham-operation group,each group’s systolic blood pressure is significantly increased(P<0.001). There was increased trend in diastolic blood pressure,but there was no statistical difference between each group(P>0.05). ②4 weeks after intervention,compared with the model group,the systolic blood pressure of perindopril group and Qianyang Decoction group both were significantly decreased(P<0.001),while the diastolic blood pressure has no statistical difference between each group(P>0.05). ③8 weeks after intervention,compared with the model group,the systolic blood pressure of perindopril group and Qianyang Decoction group both were significantly decreased(P<0.05),while the diastolic blood pressure has no statistical difference between each group(P>0.05). ④8 weeks after intervention,compared with the sham-operation group,the level of AngⅡof model group was significantly decreased(P<0.001). Compared with the model Group,the level of AngⅡof perindopril group and Qianyang Decoction group are both significantly decreased (P<0.001) Conclusion:Qianyang Decoction has antihypertension effect in rats with abdominal aortic banding,especially lower systolic pressure,the possible mechanism is by inhibiting AngII levels.关键词：“Qianyang decoction”;abdominal aortic banding;high blood pressure;AngⅡ
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发布时间：2022-08-31 - 摘要：Objective:The current research is to observe the contents change of IL-4,IFN-γ,IL-17 and IL-10 in allergic rhinitis rats’ serum,analyze the regulating role of Bimingan Prescription in the cytokines and the possible mechanism of its treatment of allergic rhinitis Methods:32 SD rats are randomly divided into blank group, model group, Bimingan group and Loratadine group. Apart from the blank group,other groups established AR rats model with OVA. When the model was established, fed the objects with normal saline, water extrat of Bimingan Prescription and Loratadine water solution. Observe the scores of rats symptoms for 7 days, 14 days and 28 days after afterwards. Detect cytokine of IL-4, IFN-γ, IL-17 and IL-10 with ELISA after the 28 days afterwards Results:7 days, 14days and 28 days after the administration, nasal symptoms of Bimingan group and Loratadine group have been more obviously relieved than the model group(P<0.01). After the model was established,the contents of IL-4 and IL-17 of model group obviously increased and the IFN-γ and IL-10 decreased(P<0.01). Compared with model group, the contents of IL-4 and IL-17 of Bimingan group and Loratadine group decreased and IFN-γ and IL-10 increased.(P<0.01) Conclusion:It showed that Bimingan Prescription was effective on treating allergic rhinitis. One of the possible mechanism of Bimingan Presciption treating allergic rhinitis was regulating the cell function balance between Th1/Th2 and Th17/Treg through influencing the contents of IL-4, IFN-γ, IL-17 and IL-10.关键词：Bimingan Prescription;allergic rhinitis;IL-4;IFN-γ;IL-17;IL-10
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发布时间：2022-08-31 - 摘要：Objective:This paper is to research antitussive, apophlegmatic and antiasthmatic effects of “Qingfei Zhikeling Syrup” on chronic bronchitis acute attack Methods:Thre Methods: were used in this experiment include the observation of cough that was induced by SO2 in mice, observation on the phlegm expelling in rats by using glass capillary and the observation of incubation period of guinea pig induced by histamine phosphate Results:“Qingfeizhikeling Syrup” can significantly prolong the mice to SO2 stimulation caused cough incubation period (P<0.05), can significantly increase the rat trachea sputum volume(P<0.05), can obviously prolong the guinea pig histamine phosphate spray out of the incubation period(P<0.05) Conclusion:“Qingfeizhikeling Syrup” of chronic bronchitis acute phase has obvious Antitussive, apophlegmatic and anti-asthmatic effect.关键词：“Qingfeizhikeling Syrup”;chronic bronchitis;acute attack;antitussive;expectorant;antiasthmatic
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发布时间：2022-08-31 - 摘要：Objective:To investigate the influence of “Laifu Chengqi Decoction” on gastrointestinal function in rats after subtotal gastrectomy Methods:Thirty SD rats were randomized into model group, treatment group and sham group, ten rats in each group. Twenty-four hours after subtotal gastrectomy, treatment group was treated with “Laifu Chengqi Decoction”(5 g/kg), sham group and model group with the same volume of saline(10 ml/kg), with a course of 21 days. The amount of food intake, body weight, and the levels of urine D-xylose and serum leptin were observed Results:①Compared with the model group, the amount of food intake and body weight were increased in the treatment group and sham group(P<0.05). ②Compared with the model group, the levels of urine D-xylose were increased and the levels of serum leptin were reduced in the treatment group and sham group(P<0.05) Conclusion:“Laifu Chengqi Decoction” can promote the restoration of gastrointestinal function after subtotal gastrectomy by increasing gastrointestinal absorption and decreasing serum leptin.关键词：“Laifu Chengqi Decoction”;subtotal gastrectomy;subtotal gastrectomy;rat
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发布时间：2022-08-31 - 摘要：Objective:This paper is to study the correlation of contents of hesperidin,limonin and nomilin from different parts of citrus with their antioxidant and anti-breast cancer cell activities Methods:The contents of hesperidin,limonin and nomilin in different parts of citrus,tangerine seed,pith and peel were detected with HPLC method. Furthermore,the in vitro antioxidant effects of the three parts of tangerine were studied with DPPH and FRA Methods:,and anti-breast cancer cell (MCF-7) activities were studied with MTT assay Results:The tangerine peel has the highest content of hesperidin,while the tangerine seed contains the highest content of limonoids. Relevant to the content study,tangerine peel has the stronger antioxidant activities in vitro than the other two,while the tangerine seed show more stronger anti-breast cancer cell activities Conclusion:The antioxidant activites of tangerine seed,pith and peel are mainly correlated with their contents of hesperidin,and the anti-breast cancer cell activities are correlated with their contents of limonins.
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发布时间：2022-08-31 - 摘要：This paper outlines the research development of the combination of Radix Aconiti Lateralis Preparata and Radix Glycyrrhiza in recent years. Research on the combination of aconite and glycyrrhiza involves the chemical components changes, effect and mechanism, absorption and metabolism, efficacy, etc, which can provide reference for the new drug research and development.关键词：Radix Aconiti Lateralis Preparata;Radix Glycyrrhiza;combination of medicines;review
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发布时间：2022-08-31 - 摘要：This paper summarizes the research development on the chemical composition, pharmacological effects of Cordyceps Militaris. The main ingredients of Cordyceps Militaris are nucleoside acid, polysaccharide, caterpillar fungus, cordycepin, sterols, amino acids and trace elements, etc., and their pharmacological effects are widely. The effects of Cordyceps Militaris on the nervous system, circulatory system and immune system are remarkable.关键词：Cordyceps Militaris;cordycepic acid;cordycepin;pharmacological aciton;review
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发布时间：2022-08-31
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