最新刊期
期 10 ， 2015
- 摘要：Objective:To investigate the effect and safety of traditional Chinese medicine formula granules (FG) and Chinese Herbs Pieces (CHP) on grade 1-2 hypertension patients Methods:227 cases were divided into treatment group (116 cases) and control group (111 cases) , the cases in treatment group were treated with traditional Chinese medicine formula granules (Compound radix scutellariae Decoction or Compound Xianmai Decoction ) while the case of control group were treated with traditional Chinese medicine slice decoction(Compound radix scutellariae Decoction or Compound Xianmai Decoction ), 1 month for each group. SBP, DBP, rate of reaching blood pressure standard, TCM syndrome score and drug safety were observed. 26 cases were rejected. The course was 4 weeks. Clinic average decline in blood pressure, rate of reaching blood pressure standard, TCM syndrome score efficacy and difference of adverse events of the two groups were analyzed by the method of non-inferiority test Results:①During the test, there were 225 case accord with FAS and in which 115 case in treatment group and 110 cases in control group; there were 201 case accord to PPS and in which 99 case in treatment group and 102 case in control group. ②In FAS and PPS, compared in each group before and after the treatment, there were statistical significance in the differences of SBP and DBP(P<0.05), but there was no statistical significance in the differences of SBP and DBP between the two groups(P>0.05), and non-inferiority test was established . ③There was no statistical significance in the differences of rates of reaching blood pressure standard between the two groups(P>0.05). ④There was no statistical significance in the differences of TCM syndrome score between the two groups(P>0.05). ⑤There was no statistical significance in the differences of adverse events between the two groups(P>0.05) Conclusion:The effect of traditional Chinese medicine formula granules on grade 1-2 hypertension patients was not worse than that of traditional Chinese medicine slice decoction.关键词：essential hypertension;Chinese medicine formula granules;traditional Chinese medicine slice decoction;compound radix scutellariae decoction;compound Xianmai decoction
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发布时间：2022-08-31 - 摘要：Objective:To evaluate the therapeutic efficacy of “Jianpi Ruangan Decotion” (JRD) in treatment of HBV-related decompensated liver cirrhosis with Syndrome of spleen deficiency and blood stasis Methods:Eighty-five HBV-related decompensated liver cirrhosis patients with Syndrome of spleen deficiency and blood stasis were assigned to two groups by using a random number table:“Jianpi Ruangan Decotion” treatment group (n=43),and control group treated with Fuzheng Huayu Capsule (n=42).In all cases, the treatment course was one year.Clinical efficacy, chronic liver disease questionnaire (CLDQ), Child-Pugh grade (CPT scores), liver function,HBV-DNA, liver fibrosis index, ultrasonic examination and fibroscan test were evaluated in both groups before and after treatment Results:①The overall effective rate was 93.02% in the treatment group and 75.61% in the control group,with a difference between the two groups. ②After treatment,CLDQ,CPT scores were significant different between groups(P<0.05). ③ After treatment,the reducing of ALT, AST, TBIL, HBV-DNA and improving of ALB,CHE were significant different between groups(P<0.05).④After treatment,HA and Ⅳ-C were significant different between groups(P<0.05). ⑤After treatment,the MPV, SPV, spleen-length, spleen-thickness and CAP were significant different between groups(P<0.05) Conclusion:“Jianpi Ruangan Decotion” has a good therapeutic effect in treatment of HBV-related decompensated liver cirrhosis with Syndrome of spleen deficiency and blood stasis with improvement of the patient’s life quality, liver function and liver fibrosis index.关键词：hepatitis B;liver cirrhosis;decompensated;syndrome of spleen deficiency and blood stasis;“Jianpi Ruangan Decotion”;liver fibrosis index
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical effect of “Yuzhang Powder” umbilicaldressing plus moxibustion through ginger for non-severe aplastic anemia (NSAA) of kidney yang deficiency syndrome Methods:75 cases of NSAA of kidney yang deficiency syndrome were randomized into the treatment group (38 cases) and control group (37 cases). The control group received routine treatment, and the treatment group received routine therapy plus “Yuzhang Powder” umbilicaldressing plus moxibustion through ginger. Both two groups were treated for six months, and to observe the clinical curative effect, hemogram index [hemoglobin (Hb), white blood cell (WBC) and platelet] and serum bFGF level changes Results:①After the treatment, 69 cases were preserved, 34 cases in treatment group and 35 cases in control group. ②After treatment, Hb and WBC of the treatment group increased obviously than those of the control group (P<0.05); ③Compared between the two groups before and after the treatment, there was significant difference in the level of bFGF in peripheral serum, and the level of bFGF in peripheral serum after treatment of the treatment group was higher than that of the control group (P<0.05) Conclusion:“Yuzhang Powder” umbilicaldressing plus moxibustion through ginger can significantly relieve clinical symptoms in patients with NSAA of kidney yang deficiency syndrome, improve the hematopoietic microenvironment to a certain extent.关键词：aplastic anemia;kidney yang deficiency syndrome;navel administration;external treatment of traditional Chinese Medicine;bFGF
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发布时间：2022-08-31 - 摘要：Objective:To explore the influence of renal function, oxidative stress and inflammatory cytokines on old maintenance hemodialysis patients treated by “Shenkang Injection” Methods:88 elderly cases of maintenance hemodialysis patients were randomly divided into two groups equally. On the basis of conventional treatment, cases in control group were given pure blood dialysis, while patients in treatment group were treated by “Shenkang Injection”, and the course was 4 weeks. The patients’ renal function, oxidative stress and inflammatory factor indicators were tested and compared Results:①The levels of renal function indexes SCr, BUN, Ccr in treatment group after treatment were significantly improved than before treatment, and the difference of two groups had statistical significance (P<0.05); ②The levels of stress reaction index MDA, SOD, T-AOC, GSH-Px in treatment group after treatment were significantly improved than before treatment, these differences were statistically significant (P<0.05); ③The levels of inflammatory factor CRP, IL-6, IL-8, TNF-α in treatment group after treatment were significantly reduced than before treatment and these differences were statistically significant (P<0.05) Conclusion:“Shenkang Injection” can improve elderly maintenance hemodialysis patients with renal function, oxidative stress and inflammation.关键词：ESRD;hemodialysis;“Shenkang Injection”;renal function;oxidative stress;inflammatory factors
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发布时间：2022-08-31 - 摘要：Objective:To observe clinical effect of “Shujing Decoction”in the treatment of cold congealing and blood stasis type of primary dysmenorrheal Methods:80 patients were randomized into treatment group and control group,40 cases in each group. Treatment goup was treated with “Shujing Decoction”,and control group was treated with Compound Norethisterone Tablets and ibuprofen capsule. Course of the both groups was 3 months,with one year’s follow-up. The clinical efficacy,change of TCM symptoms were observed Results:①After treatment,the total effective rate of treatment group was 92.50%,while control group was 80.00%. A significant difference was observed between two groups(P<0.05). ②The changes of scores of TCM symptoms after treatment were different between the two groups(P<0.05). ③Compared 6 months after treatment and one year after treatment,there was no significant difference in scores of TCM symptoms in treatment group(P>0.05),while there was significant difference in scores of TCM symptoms in control group(P<0.05). Compared 6 months after treatment and one year after treatment,there was significant difference in scores of TCM symptoms between two groups(P<0.05) Conclusion:“Shujing Decoction”in treatment of cold congealing and blood stasis type of primary dysmenorrhea can relieve pain,and has longer effective time of duration.关键词：primary dysmenorrhea;cold congealing and blood stasis syndrome;“Shujing Decoction”;Compound Norethisterone Tablets;ibuprofen capsule;long-term effect
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发布时间：2022-08-31 - 摘要：Objective:To evaluate the clinical effect of TCM nursing in the perioperative period of suspension type Methods:The patients were randomly divided into observation group and control group. The control group was given routine nursing, and the observation group was treated with traditional Chinese medicine on the basis of conventional nursing. Observe the gernal situation of the patients of two groups, record the time and the average course of disease, analysis of the nursing intervention before and after the anxiety scale score, hospitalization satisfaction score, the score of hospital discharge Results:There was no significant difference in the mean age, body mass index (BMI) and clinical disease classification, anxiety score and other baseline data in the two groups (P> 0.05)；After nursing intervention, the anxiety score in the observation group was significantly decreased (P<0.05),while the control group had no significant change (P> 0.05), the observation group was significantly better than that in the control group (P<0.05)；the average length of stay in the observation group was significantly shorter than that in the control group (P<0.05)； the satisfaction and psychological status were significantly higher than those in the control group (P<0.05) Conclusion:Perioperative nursing of Chinese medicine in the treatment of gynecological laparoscopic operation can improve the symptoms of anxiety, shorten hospitalization time, improve clinical symptoms, improve patient satisfaction and psychological status of patients.关键词：suspension type laparoscope;perioperative period;nursing care of Traditional Chinese Medicine
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of “Pinggan Yangfei Zhike Decoction” with massage on treatment of infantile anaphylactic cough Methods:52 cases of infantile anaphylactic cough were randomly divided into treatment group and control group equally. Cases in treatment group were treated by “Pinggan Yangfei Zhike Decoction” with massage and cases in control group were treated with normal western medicine,for two courses with 2 weeks in a course. The clinical efficacy and the content of IgE before and after the treatment were observed Results:The total effective rate was 88.4% in treatment group and 57.6% in control group; there was significant difference of the clinical efficacy between the two groups (P<0.05). after the treatment, the content of IgE in treatment group decreasing significantly than before the treatment(P<0.01), and lower than that of control group(P<0.01) Conclusion:“Pinggan Yangfei Zhike Decoction” with massageon was quite effective for infantile anaphylactic cough and could decrease the content of IgE .关键词：infantile anaphylactic cough;“Pinggan Yangfei Zhike Decoction”;massage;IgE
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical curative effect of “Huashen Mixture” combined with Clarityne in treating wind-heat urticaria Methods:129 cases of wind-heat urticaria were paired randomly divided into two groups, the control group of 65 cases was treated with Clarityne, while on this basis the observation group of 64 cases was added with “Huashen Mixture”. During one month’s treatment, the clinical symptom score was evaluated and compared, including the number and diameter of wheal, the frequency and duration of wheal, the degree of itching, and the clinical curative effect also was compared between these two groups Results:①The clinical curative effect of the observation group was 100.00%, the control group was 96.92%; the differences were significant (P<0.05). ②After treatment, the number, the diameter, the duration of wheal and the degree of itching scores were significantly lower in the observation group than in the control group (P<0.05). ③After treatment, the frequency of wheal was significantly lower in the observation group than in the control group (P<0.05) Conclusion:Combination “Huashen Mixture” and Clarityne in treating wind-heat urticaria can significantly improve the clinical symptoms, reduce the frequency of wheal.关键词：Urticaria;wind-heat syndrome;“Huashen Mixture”;Clarityne;the frequency of wheal onset
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发布时间：2022-08-31 - 关键词：Monkshood;Astragalus;insect drugs;carbon drugs;famous doctor’ s experience;Xie Jianguo.
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发布时间：2022-08-31 - 摘要：With the increasing numbers of depressives,the therapeutic strategies should be taken into further consideration. Soothing the liver and regulating the flow of qi,as well as invigorating the heart to tranquilize mind should be regarded as the mai Methods:. Facing the depressives with various and universal manifestations,differentiation and diagnosis cannot be treated inflexibly but flexible. The weird symptoms are one of the main features of depression syndrome,we put forward the view of treating weird symptoms from the aspect of depression is on the basis of treating weird symptoms from the aspects of sputum and blood stasis. To the patients with the coexistence of diseases and depression syndrome,treating both diseases and depression should be emphasized, at the same time, psychotherapy should also be combined.关键词：depression syndrome;weird symptoms;soothing the liver and regulating the flow of qi;invigorating the heart to tranquilize mind;treating from the aspect of depression;psychotherapy
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发布时间：2022-08-31 - 摘要：In this paper, we analyze the application of combined Chinese formula, and by adopting the philosophy of TCM, argue that its philosophical source is parallelism between prescription and syndrome, which embodies the TCM philosophy thought of image-numerology and intuition. Combined Chinese formula is based on pathogenesis of disease, pathogenesis condition, aims to improve efficiency, and embodies unity thinking, neutral thinking, changing thinking and function thinking of TCM. The application of combined Chinese formula came into being on the basis of philosophical thought of TCM; meanwhile it reflects the clinical application of the philosophical thought of TCM.关键词：combined Chinese formula;TCM;philosophical thinking;parallelism between prescription and syndrome
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发布时间：2022-08-31 - 摘要：Objective:To describe the kinematics and dynamics parameters of cervical traction manipulation Objective:ly and provide the exact data for the regularity research of cervical massage manipulation Methods:A chief physician worked for more than 25 years of massage speciality acted as the performer and nine healthy volunteers were selected as the subjects. The performer applied cervical traction manipulation in the healthy volunteers and the kinematics and dynamics parameters of cervical traction manipulation were collected by motion-capture-system and force platform Results:In the course of cervical traction manipulation, the average stretching length of the cervical spine was (8.80±3.09) mm and the average stretching angle of the cervical spine was (16.67±6.61)°; the average pelma resultant force of the performer was increased (353.76±44.08) N and the average pelma resultant force of the subject was reduced (353.48±45.29) N Conclusion:Cervical traction manipulation has some regularity on the dynamics and kinematics parameters, and it provides the reference for the massage manipulation.关键词：cervical traction manipulation;kinematics;dynamics
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发布时间：2022-08-31 - 关键词：bronchiectasis;cough;teaching ward round
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发布时间：2022-08-31 - 关键词：dysmenorrhea;treatment on syndrome differentiation;famous doctor’s experience;Zhu’s department of gynaecology;Hu Guohua
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发布时间：2022-08-31 - 摘要：This article summarized and arranged the clinical experience of Mr. Bian Songjing differentiation and treatment of chronic atrophic gastritis with intestinal metaplasia. It is believed that the deficiency of Zhongyang and phlegm stagnation and blood - stasis are the etiology of this disease, and warming and nourishing Zhongyang and activating blood analgesia are the therapy of this disease. This disease can be classified into deficiency and cold of Zhongyang, deficiency and stagnation of qi, cold-coagulation blood-stasis and deficiency of both qi and yin. A proven case was listed.关键词：chronic atrophic gastritis with intestinal metaplasia;gastric cancer;gastric abscess;clinical experience;Bian Songjing
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发布时间：2022-08-31 - 摘要：This paper analyses the components, efficacy, clinical application and working mechanism of “Yiyi Fuzi Baijiangsan”. This prescription is applied not only in treatment of such diseases as Ulcerative Colitis, Appendicitis, but also in bronchiectasis, Chronic Prostatitis, Oral ulcer, chronic eczema, chronic pelvic inflammation, pelvic cyst.关键词：classical prescription;“Yiyi Fuzi Baijiangsan”;clinical appliation
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发布时间：2022-08-31 - 摘要：Based on the analysis on the original texts about the spleen-stomach function adjustment in General Treatise on the Etiopoly and Symptomology of Diseases, and with the author’s practicing experience, six characters of Daoyin General Treatise on the Etiopoly and Symptomology of Diseases adjusting spleen-stomach functions are concluded as below:three adjustments in one; keeping back and waist in moderate tension; relaxing abdomen; body’s to-and-fro motion; paying more attention to expiration; one symptom with one manipulation.关键词：General Treatise on the Etiopoly and Symptomology of Diseases;spleen-stomach;Daoyin;characteristics
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发布时间：2022-08-31 - 摘要：This paper reviews “Shanghan” according to the recordings in General Treatise on the Etiopoly and Symptomology of Diseases, forms a panorama view about the disease, exams the symptoms, and explores the disease from the perspective of modern knowledge. Furthermore, this paper reads “Shanghan” with contrast and supplement of Treatise on Febrile and Miscellaneous Diseases, to further the understanding of its origin, clinical treatment, and its evolution at different times.关键词：General Treatise on the Etiopoly and Symptomology of Diseases;Treatise on Febrile and Miscellaneous Diseases;Shanghan
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发布时间：2022-08-31 - 关键词：exophthalmos;prunella vulgaris;dried alum;famous doctor’s experience;Tong Xiaolin
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发布时间：2022-08-31 - 摘要：This paper aims to discuss etiology, pathogenesis and principle of treatment of pulmonary interstitial fibrosis, and propose differentiation at different stages. In the early stage it should be treated in dispersing Lung-Qi while in the middle stage it should be treated in dissipating phlegm and in the late stage it should be treated in strengthening the body resistance to eliminate pathogenic factors. We can achieve bette Results: by treatment based on syndrome differentiation.关键词：pulmonary interstitial fibrosis;lung impediment;differentiation at different stages
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发布时间：2022-08-31 - 关键词：astringing method;hair loss;TCM therapy
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发布时间：2022-08-31 - 摘要：The paper discussed traditional Chinese medicine’ point on menopausal syndrome’s pathogenesis, as well as the basic principle and herbs. And summarized the study of (Heyan)Kuntai Capsule’s clinical efficacy and mechanism on treating in menopause, indicating that it’s effective and safety when treating in menopausal syndrome, worthy of clinical application.关键词：menopause;ovarian failure;Kuntai Capsule
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发布时间：2022-08-31 - 摘要：Objective:To investigate the inhibitory effects of different doses of Astragalus membranceus on the oxidative stress in the kidneys of diabetic rats Methods:Totally 40 healthy male Wistar rats were used, from which 8 rats were randomly selected as normal control group. Then the rest rats were induced to diabetic rat models by injections of streptozotocin, and the successful models were divided randomly into four groups:the diabetes mellitus group, the low dosage Astragalus membranceus (Al) group, the middle dosage Astragalus membranceus (Am) group and the high dosage Astragalus membranceus (Ah) group. After 12 weeks of intervention, the biochemical test was used to measure the levels of 24-hour urine protein quantitate, renal function, and other tests were done to measure the activity of superoxide dismutase (SOD), the content of malondialdehyde (MDA) and 8-hydroxy-deoxyguanosine (8-OHdG) in the renal cortex Results:The content of MDA and 8-OHdG in the Astragalus membranceus treatment groups were markedly lower and SOD activity significantly increased than those in the diabetes mellitus group (P<0.05, P<0.01), and renal function improved significantly (P<0.01), and pathological changes obviously alleviated; the Astragalus membranceus treatment high dose group improved most obviously than other groups Conclusion:The traditional Chinese herbal medicine Astragalus membranceus could inhibit the oxidative stress in the kidneys of diabetic rats with an obvious dose-effect relationship.关键词：Astragalus membranceus;diabetic nephropathy;oxidation stress;8-hydroxy-deoxyguanosine;dose-effect relationship
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发布时间：2022-08-31 - 摘要：Objective:To observe the effects of Warming Kidney and Tonifying Spleen interventions on IBS-D rats’ colonic mucosa, ileocecal CCK and MOT to probe into the underlying mechanism from the gastrointestinal hormone perspective Methods:48 rats were randomly divided into normal group, model group, Warming Kidney and Tonifying Spleen high, middle and low dose groups, and control group, 8 in each group. Referencing AL-Chaer modeling,made a duplicate IBS-D rat model. After that, the treatment groups were treated with high dose, middle dose and low dose Decocting-free Warming Kidney and Tonifying Spleen formula decoction, while the control group was treated with Decocting-free “Sishen Pill”, and the model group was treated with equal quantity of normal saline irrigation, 2 weeks for each group. The general situation of rats in each group was observed, and immunohistochemistry analysis was employed to observe the changes in their colonic mucosa,ileocecal CCK and MOT Results:After the treatment, the general situation of rats in each group became better to various degree, and the situation of rats in the Warming Kidney and Tonifying Spleen high and middle groups was better than that of the low dose and control groups. Compared with normal group, the expression of colonic mucosa, ileocecal CCK and MOT in the rats in model group increased , and there was significant statistic difference(P<0.05). Compared with model group after the treatment, the expression of colonic mucosa, ileocecal CCK and MOT in the rats in the Warming Kidney and Tonifying Spleen high, middle and control groups decreased. Compared with low dose group, the expression of colonic mucosa, ileocecal CCK and MOT in the rats in the Warming Kidney and Tonifying Spleen high, middle groups decreased, and there was significant statistic difference(P<0.05) Conclusion:Warming Kidney and Tonifying Spleen interventions proved to be effective to reduce the quantity of colonic mucosa and the amount of released ileocecal CCK and MOT, which in turn reduces the intestinal sensitivity and also accelerate the degradation of CCK and MOT present in their body.关键词：diarrhea-predominant irritable bowel syndrome/IBS-D;TCM therapy;Warming Kidney and Tonifying Spleen Interventions;cholecystokinin/CCK;motilin/MOT
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发布时间：2022-08-31 - 摘要：Objective:To investigate the suppression effect on the DNMTs gene by curcumin in pancreatic cancer cell PANC-1 cells and its mechanism Methods:The PANC-1 cell line was divided into control group, gemcitabine group, curcumin group and combination group. After 48 hours intervention CCK8 assay was to detect the proliferation PANC-1 cells. The expression of DNMT1 and DNMT3 mRNA were detected by RT-PCR; the expression of DNMT1 and Caspase-3 protein were detected by Western blotting Results:①Compared with gemcitabine group and curcumin group, the combination group inhibited the PANC-1 cell significantly higher(P<0.05). ②Compared with the control group, the expression of mRNA of DNMT1 and DNMT3RT-PCR of gemcitabine group, curcumin group and combination group was lower(P<0.05), while the combination group was lower than that of gemcitabine group and curcumin group(P<0.05). ③Compared with the control group, the expression of DNMT1 of gemcitabine group, curcumin group and combination group was lower(P<0.05,P<0.01), while the expression of Caspase-3 was higher(P<0.01), and there was significant difference between the combination group and the groups of gemcitabine and curcumin(P<0.05) Conclusion:The therapy of combination of gemcitabine and curcumin can synergistically down-regulated the DNMT1 and DNMT3 gene expression of mRNA,down-regulated the protein expression of DNMT1,which could via up- regulated the expression of Caspase-3 in the PANC-1 cell line.
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发布时间：2022-08-31 - 摘要：Objective:To explore the effects of “Huangqi Guizhi Wuwu Decoction”(HGWD)on myocardial cell in ischemia reperfusion injury to study its protective function Methods:An anoxia/reoxygenation model of myocardial cells in Wistar rats was established.The experiment was divided into 6 groups:normal group, model group, control group,HGWD of high-, medium-and low-dose groups. Normal group and model group were given saline by gavage; control group was given same amount of Compound Danshen dripping pill solution by gavage(0.075 g·kg-1·d-1); HGWD groups were respectively given equivalent amount of high(9.0 g·kg-1·d-1),medium (4.5 g·kg-1·d-1) and low(2.25 g·kg-1·d-1) dose of HGWD; 3 days after intragastric administration,draw blood from abdominal aorta to prepare drug-containing serum. The use of drugs containing different concentrations of hypoxic preconditioning 1h medium, hypoxia reoxygenation injury model was set up for each experimental group. The CK activity, NO content, SOD activity and MDA content were observed; Realtime PCR was used to detect the expressions of Bcl-2 and Bax mRNA; Western blot was adopted to detect the expressions of Bcl-2 and Bax protein Results:“Huangqi Guizhi Wuwu Decoction” could reduce CK activity, NO and MDA contents, and increase SOD activity in myocardial cells with hypoxia reoxygenation injury; it could also reduce theexpressions of Baxprotein and mRNA, and increase theexpressions of Bcl-2 mRNA and protein Conclusion:“Huangqi Guizhi Wuwu Decoction” exert protective effects on myocardial cells with ischemia reperfusion injury.关键词：“Huangqi Guizhi Wuwu Decoction”;myocardial cell;ischemia reperfusion injury;hypoxia reoxygenation
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发布时间：2022-08-31 - 摘要：Objective:To explore the mechanism of tuina for curing fracture nonunion Methods:40 SD rats were made of the right hind leg fracture nonunion models, then they were randomly divided into model group and tuina group, 20 in each group. The model group without treatment, while the tuina group was received the corresponding skills in 10 weeks continuous treatment. Rats in each group were respectively sacrificed for TNF-ɑ, IL-6 and collagen type I levels test at the third week and the tenth week. Right hind limb X-ray photos were given to all of the samples finally Results:The serum IL-6 and TNF-ɑ of the tuina group compared with the model group was significantly higher at the third week(P<0.05) and the collagen type I of the tuina group was also higher at the tenth week(P<0.05). The tuina group X-ray showed the fracture line was fuzzy, with varying degrees of callus growth, but the model group still kept nonunion Conclusion:Tuina could significantly improve the content of serum TNF-α and IL-6 at front stage(the third week), stimulate inflammation reaction to induce porosis; and at the late stage(the tenth week) tuina can promote the collagen type Ⅰ synthesis, accelerate bony callus growth and fracture healing.关键词：Tuina;fracture nonunion;TNF-ɑ;IL-6;inflammation
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发布时间：2022-08-31 - 摘要：Objective:To optimize and establish the best decocting technology of “Compound Shihu Qingfei Powder” by method of orthogonal design Methods:HPLC and The complete L9(33) orthogonal design were used to optimize the decocting technology of “Compound Shihu Qingfei Powder”,including water solvents,decocting times and time；the paste-froming rate and content of hesperidin were monitored Results:The best decocting technology was that using 10 times amount of water, soaking for 35 minutes decocting 3 times, 1 hour for each time of decocting. It was shown that the linear relationship of hesperidin was good in 66.93~334.67mg/L, and the precision test,the sample stability test and the repetitive experiment were well Conclusion:The decocting technology of “Compound Shihu Qingfei Powder” was stable, feasible and reliable,which could provide reference for actual production.关键词：“Compound Shihu Qingfei Powder”;orthogonal design;hesperidin;decocting technology
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发布时间：2022-08-31 - 摘要：This paper aims to comprehensively summarize the underlying mechanism of the biological treatment in rat model for heart failure by Astragalus mongholicus and derivates thereof. It is believed that Astragalus mongholicus and derivates thereof may treat chronic heart failure in rat model in a “multi-path and multi-target” way, and the action mechanism of which include improving heart function and energy metabolism, intervention in neuroendocrine system, inhibition calcium overloading, heart failure related cytokines and cardiac hypertrophy, decreasing oxygen-derived free radicals content and myocardial apoptosis, etc.关键词：Astragalus mongholicus;rat;heart failure;protective effects;review
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发布时间：2022-08-31 - 摘要：This paper reviews the research progress on the extraction method and pharmacological action of proanthocyanidin. The main extraction method of proanthocyanidin include organic solvent extraction method, ultrasonic extraction, enzymes extraction and supercritical fluid method. The pharmacological action of proanthocyanidin include regulating immune, anti-inflammation, lipid lowering and live protection, protection of intestinal injury and brain function, prevention and cure atherosclerosis, Uv reactive skin protection, nervous system protection and eye protection, etc.关键词：proanthocyanidin;extraction method;physiological action;review
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发布时间：2022-08-31
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