最新刊期
期 1 ， 2015
- 摘要：This paper introduces Prof. Liu's experience with chronic aplastic anemia based on kidney theory. It is believed that kidney deficiency is the key pathogenesis of aplastic anemia, which can be divided into three types:kidney yin deficiency type, kidney yang deficiency type and both deficiency of kidney yin and kidney yang type. Comprehensive therapeuti Methods: including “acupuncture, drug, acupoint sticking therapy at Shenshu, auricular seed pressing, differentiation and treatment” should be applied. This paper concludes the characteristics of treating aplastic anemia. It is worthy of clinical application.关键词：chronic aplastic anemia;kidney deficiency;famous doctor's experience;Liu Baowen
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发布时间：2022-08-31 - 摘要：This paper introduces Professor Guo's experience in differentiating and treating asthenospermia with four patterns. It is suggested that asthenospermia was classified into four patterns:deficiency of kidney qi pattern, both deficiency of spleen and kidney deficiency pattern, stagnation of phlegm and dampness, deficiency of liver and kidney. Therapeuti Methods: such as enriching the kidney and liver, strengthening the spleen, resolving phlegm and excreting dampness should be paid attention to.关键词：asthenospermia;clinical experience;Guo Jun
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发布时间：2022-08-31 -
- 摘要：Objective: To observe the clinical efficacy of “Yuzhang Powder” moxibustion on umbilicus for the treatment of chronic aplastic anemia of kidney-yang deficiency pattern Methods: Seventy cases with chronic aplastic anemia of kidney-yang deficiency pattern were randomized into treatment group and control group, with 35 cases in each group. Control group was treated with conventional therapy, and treatment group was treated with “Yuzhang Powder” moxibustion on umbilicus additionally, with the course of 6 months. The clinical efficacy, indicators of Hb, WBC, PLT and levels of IL-17 and IL-17 mRNA were observed Results: ①At the end of the treatment, 63 cases completed the trial. Thirty-two patients in the treatment group and 31 cases in the control group. ② The overall effective rate was 87.50% in the treatment group and 61.29% in the control group, with a difference between the two groups (P<0.05). ③ In both groups, there were significant differences in the levels of Hb, WBC and PLT between before and after treatment (P＜0.05); after treatment, there were significant differences in the levels of Hb and WBC between the two groups, and the treatment group was superior to the control group (P＜0.05). ④ In both groups, there were significant differences in the IL-17 level of the serum and relative value of IL-17 mRNA in thymus-dependent lymphocytes of peripheral blood between before and after treatment (P＜0.05); after treatment, there were significant differences in the IL-17 level of the serum and relative value of IL-17 mRNA in peripheral blood between the two groups, and the treatment group was superior to the control group (P＜0.05). ⑤ No adverse reaction was found in both groups Conclusion: “Yuzhang Powder” moxibustion on umbilicus is effective to patients with chronic aplastic anemia of the kidney-yang deficiency pattern. Its mechanism may be assication with the decrease of IL-17 level and the expression of IL-17 mRNA in the peripheral blood T-lymphocytes.关键词：aplastic anemia;“Yuzhang Powder”;umbilicus;moxibustion;IL-17 mRNA
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发布时间：2022-08-31 - 摘要：Objective: To observe the clinical efficacy of “Banxia Xiexin Decoction” and “Sini Powder” in treating reflux esophagitis Methods: One hundred and thirty-nine cases with flux esophagitis were randomly divided into treatment group and control group. Control group in which 69 cases were treated with omeprazole and domperidone, and treatment group in which 70 cases were treated with “Banxia Xiexin Decoction” and “Sini Powder”, with the course of 3 months. The curative effect and recurrence rate were observed and the TCM symptom scores were compared Results: ①The total effective rate was 85.71% in the treatment group and 60.87% in the control group, with a difference between the two groups (P<0.05). ② In both groups, there were significant differences in the symptom scores and the total scores after treatment (P＜0.05); after treatment, there were significant in scores of symptoms such as pain, acid regurgitation, belching, heartburn, bitter taste, dry mouth in precordium and substernal parts between the two groups (P＜0.05). ③ The recurrence rate was 15.15% in the treatment group and 38.10% in the control group, with a difference between the two groups (P<0.05) Conclusion: Combined “Banxia Xiexin Decoction” and “Sini Powder” can release the clinical symptoms, and with low recurrence rate for the treatment reflux esophagitis.关键词：Keywords:reflux esophagitis;“Banxia Xiexin Decoction”;“Sini Powder”;omeprazole;recurrence rate
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发布时间：2022-08-31 - 摘要：Objective: To observe the clinical efficacy of western routine treatment and Chinese liver-protection exercises for the treatment of liver fibrosis following chronic hepatitis B Methods: Two hundred and thirty-eight cases were randomized into treatment group (120 cases) and control group (118 cases). Both groups were treated with western routine therapeutic regimen, and treatment group was added with Chinese liver-protection exercises, with the course of 6 months. The clinical efficacy, indexes of liver function and hepatic fibrosis were observed Results: The total effective rate was 88.3% in the treatment group and 71.2% in the control group, the comprehensive clinical efficacy in the treatment group was superior to the control group (P<0.05). In both groups, there were significant differences in the levels of ALT, AST, TBIL and Alb between before and after treatment (P<0.05); after treatment, there were significant differences in the levels of ALT, AST and Alb between the two groups (P<0.05). In both groups, there were significant differences in the levels of HA, LN, PCIII and CIV between before and after treatment (P<0.05); after treatment, there were significant differences in all indexes between the two groups (P<0.05) Conclusion: Combination of routine treatment and Chinese liver-protection exercises can improve the liver fibrosis following chronic hepatitis B, and prevent earlier cirrhosis.关键词：chronic hepatitis B;hepatic fibrosis;integrated Chinese and western medicine;Chinese liver-protection exercises
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发布时间：2022-08-31 - 摘要：Objective: To observe the clinical efficacy of “He's Xinfang Jindan Decoction” in treating fatty liver Methods: Eighty cases with fatty liver of the dampness-heat of liver and gallbladder pattern were treated with “He's Xinfang Jindan Decoction”, with the course of 12 weeks. The clinical efficacy was observed after treatment, and was followed-up for 12 weeks after drug withdrawal Results: The total effective rate was 93.75% after treatment and was 86.25% in follow-up Conclusion: “He's Xinfang Jindan Decoction” has positive effects on fatty liver of dampness-heat of liver and gallbladder pattern, either in short-term or long-term.关键词：“He's Xinfang Jindan Decoction”;fatty liver;dampness-heat of liver and gallbladder
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of needle knife lytic method on suboccipital muscles in treating cervical vertigo Methods:One hundred and twenty cases with cervical vertigo were randomized into treatment group and control group, with 60 cases in each group. Control group was treated by conventional acupuncture treatment, and treatment group was treated by needle knife lytic method on suboccipital muscles, with the course of 20 days. The clinical efficacy, scores of Visual Analogue Scale (VAS) and Dizziness Handicap Inventory (DHI) were observed Results:① The total effective rate was 88.33% in the treatment group and 65.00% in the control group, with a difference between the two groups (P<0.05). ② In both groups, there were significant differences in the scores of VAS and DHI between before and after treatment (P＜0.05); after treatment, there were significant differences in the scores of VAS and DHI between the two groups, and treatment group was superior to the control group (P＜0.05) Conclusion:Needle knife lytic method on suboccipital muscles can effectively relieve the symptoms of cervical vertigo.关键词：cervical vertigo;needle knife lytic method;suboccipital muscle;dizziness handicap inventory (DHI)
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发布时间：2022-08-31 - 摘要：Objective: To observe the clinical efficacy of “Gegen Injection” on cerebral arteriosclerosis and its effect on hemorheology indexes Methods: Eighty-seven cases with cerebral arteriosclerosis were randomized into treatment group and control group. Forty-three cases in the control group were treated with Nimodipine Tablets and Aspirin Enteric-coated Tablets orally, and cases in the treated group were added with “Gegen Injection”, with the course of 3 weeks. The clinical efficacy and changes of blood lipid and hemorrheology indexes were observed before and after treatment Results: The total effective rate was 93.18% in the treatment group and 72.09% in the control group, with a difference in clinical efficacy between the two groups (P<0.01). In both groups, the indexes of blood lipid and hemorrheology were improved after treatment (P<0.05), and the improvement of the treatment group was superior to the control group (P<0.05) Conclusion: “Gegen Injection” is effective to improve the clinical efficacy and improve the blood lipid and hemorrheology indicators in patients with cerebral arteriosclerosis.关键词：“Gegen Injection”;cerebral arteriosclerosis;hemorrheology
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发布时间：2022-08-31 - 摘要：Objective: To evaluate the effect of Nan's breath-regulating method and drug therapy on blood pressure and psychology in patients who suffered from cancer and complicated with hypertension.Methods Fourteen cases with cancer and hypertension were recruited by self-contrast method.On the basis of conventional treatment, Nan's breath-regulating method was added for three months.The systolic pressure, diastolic pressure and SCL-90 score were observed.Results After treatment, the systolic pressure was reduced (P<0.05), and symptom scores of somatization, obsessive-compulsive, sensitive of interpersonal relationship, depression, anxiety, antagonistic feeling, horrible, and stubborn were reduced markedly (P<0.05).Conclusion Combined Nan's breath-regulating method and drug therapy is effective to lower the systolic pressure of patients with cancer and hypertension, and up-regulate their psychology.关键词：cancer;hypertension;Nan's breath-regulating method;psychology
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发布时间：2022-08-31 - 摘要：Objective:To observe the clinical efficacy of “Gegen Huzhang Decoction” in treating ventricular premature beat (VPB).MethodsOne hundred cases with VPB were randomized into treatment group and control group, with 50 cases in each group.Control group was treated with Mexiletine Hydrochloride Tabltes orally, and treatment group was treated with “Gegen Huzhang Decoction” orally, with the course of 4 weeks.The clinical efficacy and frequency of VPB were observed in both groups.ResultsThe total effective rate was 90.0% in the treatment group and 74.0% in the control group, with a difference in clinical efficacy between the two groups(P<0.05).After treatment, the frequency of VPB was decreased in both two groups (P<0.05, P<0.01), and the frequency of VPB in the treatment group was less than that of the control group (P<0.05).Conclusion“Gegen Huzhang Decoction” has positive effect on VPB.关键词：ventricular premature beat (VPB);“Gegen Huzhang Decoction”;clinical observation
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发布时间：2022-08-31 - 摘要：Objective: To observe the clinical efficacy of “Yajia Formula” for the treatment of subacute thyroiditis of the blood heat with blood stasis pattern.Methods Sevnety cases with subacute thyroiditis were randomized into treatment group and control group, with 35 cases in each group.Control group was treated with Prednisone Acetate Tablets orally, and treatment group was treated with “Yajia Formula” orally, with the course of 2 months.The clinical efficacy, adverse reactions, recurrence rate were observed, and the effect of individual symptoms, changes of related blood biochemical indexes (including leukocyte, neutrophil, C-reactive protein, erythrocyte sedimentation rate), and related thyroid gland indicators (FT3, FT4, TSH) were compared and analyzed.Results ① Sixty patients finished the experiment at the end of treatment, 30 cases in the treatment group and 30 cases in the control group.② The total effective rate was 90.00% in the treatment group and 73.33% in the control group, with a difference between the two groups(P<0.05).③ In both groups, the individual symptoms were improved, with significant difference between before and after treatment (P＜0.05).After treatment, there were significant differences in goiter, weakness, hidrosis, pain limbs, poor appetite between the two groups, and the improvement in the treatment group was superior to that of the control group (P＜0.05); no significant difference was found in fever, thyroid pain, tremble, pharyngalgia between the two groups (P＞0.05).④ In both groups, there were significant differences in leukocyte, neutrophil, C-reactive protein and erythrocyte sedimentation rate between before and after treatment (P＜0.05).After treatment, there were significant differences in the value of leukocyte, neutrophil, C-reactive protein and erythrocyte sedimentation rate between the two groups (P＜0.05).⑤ In both groups, there were significant difference in the levels of FT3, FT4 and TSH between before and after treatment (P＜0.05); After treatment, no significant difference was found in the levels of FT3, FT4 and TSH between the two groups (P＞0.05).⑥ The adverse effective rate of the treatment group was superior to that of the control group (P＜0.05).⑦ The recurrence rate in the treatment group was superior to that of the control group (P＜0.05).Conclusion “Yajia Formula” can relieve the clinical symptoms and reduce inflammation reaction in treating subacute thyroiditis of the blood heat with blood stasis pattern with less adverse reactions and recurrence rates.关键词：subacute thyroiditis;“Yajia Formula”;blood heat with blood stasis pattern;recurrence rate;adverse reaction
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发布时间：2022-08-31 - 摘要：Objective: To observe the clinical efficacy of “Ertong Huichun Granules” in treating herpangina in children.Methods One hundred and thirty-two children with herpangina were randomized into treatment group and control group, with 66 cases in each group.Both groups were treated with conventional therapy, and treatment group was added with “Ertong Huichun Granules”, with the course of 7 days.Results The overall effective rate was 95.5% in the treatment group and 75.8% in the control group, with a difference between the two groups (P<0.05), the clinical efficacy in the treatment group was superior to the control group.The fever time, salivation disappearance time, simplex regression time in the treatment group were less than those of the control group (P<0.05).Conclusion “Ertong Huichun Granules” is effective to improve the clinical efficacy and shorten the course of herpangina.关键词：herpangina;“Ertong Huichun Granules”;child
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发布时间：2022-08-31 - 摘要：Objective: To observe the clinical efficacy of “Compound Danfu Ointment” and fumigating-steaming therapy in treating chilblain at Great heat.Methods At the day of Great heat, cases in the treatment group were treated with the combination of “Compound Danfu Ointment” and fumigating-steaming therapy, and cases in the control group were treated with Vaseline and fumigating-steaming therapy, with the course of 10 days.The clinical efficacy, scores of skin lesion and subjective symptoms were observed before and after treatment.Results The total effective rate was 71.93% in the treatment group and 36.67% in the control group, with a difference between the two groups (P<0.05).After treatment, the scores of skin lesion were reduced in the treatment group (P<0.01), and scores of skin lesion in the treatment group were lower than that of the control group (P<0.05); the subjective symptom scores were reduced in the treatment group (P<0.01), and were lower than that of the control group (P<0.05).Conclusion Combined “Compound Danfu Ointment” and fumigating-steaming therapy can prevent or alleviate the chilblain at Great heat.关键词：chilblain;“Compound Danfu Ointment”;fumigating-steaming therapy with Chinese medicine;Great heat;treating the winter diseases in summer
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发布时间：2022-08-31 - 摘要：Objective: To observe the clinical efficacy of combined Chinese medicine therapy for the treatment of cervical spondyloticradiculopathy.Methods One hundred and forty-six cases were randomized into treatment group and control group, with 73 cases in each group.Control group was treated with conventional therapy (diclofenac sodium plus mecobalamine), and treatment group was treated with combined Chinese medicine therapy (small needle-knife, tuina and “Xuefu Zhuyu Decoction”), with the course of 1 month.The clinical efficacy, recurrence rate VAS score, and specific sign were observed.Results ① The total effective rate was 89.04% in the treatment group and 73.97% in the control group, with a difference between the two groups (P<0.05).② In the treatment group, there were significant differences in VAS scores between before treatment and after 2 weeks treatment (P<0.05); in each group, there were significant differences in VAS scores between before and after 4 weeks treatment (P<0.05).After 4 weeks treatment, there were significant differences in VAS between the two groups (P<0.05).③ In each group,there were significant differences in the negative conversion ratio of the head taps test, Eaten test, Spurling test between before and after 2 weeks treatment, and between before and after treatment (P<0.05).there were both significant differences in the negative conversion ratio of the head taps test, Eaten test, Spurling test between the two groups after treatment and after 2 weeks treatment between the two groups (P<0.05).④ The recurrence rate was 13.64% in the treatment group and 35.29% in the control group, with a difference between the two groups (P<0.05).Conclusion Combined Chinese medicine therapy can obviously alleviate shoulder and neck pain, with a lower ratio of recurrence.关键词：cervical spondylotic radiculopathy;small needle-knife;Tuina;“Xuefu Zhuyu Decoction”;recurrence rate
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发布时间：2022-08-31 - 摘要：Property of dynamic and static, rigid and flexible are the important part of characteristics of Chinese materia medica.To expound the characteristic of property in Chinese materia medica and relationship of dynamic-static and rigid-flexible, compatibility of medicines and application of dynamic-static drugs and rigid-flexible drugs has enriched and developed the theory of compatibility of medicines.
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发布时间：2022-08-31 - 关键词：stomach diseases;famous doctor's experience;Wu Shentao
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发布时间：2022-08-31 - 摘要：This paper introduces Prof. Huo Qingping's clinical experience in treating gallbladder diseases. It is believed that gallbladder diseases located in gallbladder and generated by liver disorder. Dispersing stagnated liver qi is the therapeutic method. “Shugan Lidan Formula” is created and applied in clinic.关键词：gallbladder disease;“Shugan Lidan Formula”;clinical experience;Huo Qingping
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发布时间：2022-08-31 - 摘要：This paper explores the mechanism and clinical application of diaphoresis. Based on the related prescriptions in Treatise on Cold Pathogenic Diseases and Monographs on Warm Diseases, we researched the diaphoretic prescriptions and Zang-fu organs treated by diaphoresis. “Opening the pores, dredging the channel, regulating qi circulation and boosting healthy qi” are the key points of diaphoresis. The symptoms, administration, nursing, contradiction, treatment and cure were concluded, which supplies references for clinical application in clinic.
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发布时间：2022-08-31 - 摘要：This paper proposes the hypothesis of sweat pore. It is believed that block of sweat pore is one of the pathogenesis of proteinuria. Herbs with pungent taste have the effect of dredging sweat pore and inhibiting proteinuria. This paper analysizes the significance of “pungent dredging sweat pores” in treating proteinuria and explores new clinical strategies for the treatment of this disease.关键词：renal Xuanfu (sweat pore) theory;proteinuria;pungent herb
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发布时间：2022-08-31 - 关键词：vaginal flatus;“Shaoyao Gancao Decoction”;clinical proven case
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发布时间：2022-08-31 - 关键词：interstitial lung diseases;Chinese medicine;medical record
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发布时间：2022-08-31 - 摘要：This paper introduces clinical cases and summarizes the prescriptions in Treatise on Spleen and Stomach for the treatment of spleen and stomach disorders and miscellaneous diseases.关键词：“Zhishi Xiaopi Pill”;“Qingshu Yiqi Decoction”;“Zhongman Fenxiao Pill”;“Shengyang Yiwei Decoction”;clinical experience
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发布时间：2022-08-31 - 摘要：Objective: To evaluate the inhibitory effect of “Jinfukang Decoction” on lung cancer stem cell proliferation and tumorigenesis, and to explore its effect on multidrug related protein expression regulation Methods: Immunomagnetic beads was applied to sorting the Sca-1+ Lewis lung cancer cell. In vitro study conducted to assess the inhibitory of the cell proliferation by MTT, with a serum containing the ingredients of “Jinfukang Decoction” as the intervention; Western-Blotting and RT-PCR were used to observe the effect of reversing the expression of multidrug resistance ABCG2 Results: In vitro study founded that “Jinfukang Decoction” was able to inhibit the proliferation of the cell with time-dependent manner, and was also able to induce the apoptosis of the Sca-1+ Lewis lung cancer cell, comparing with a control group (P<0.05). “Jinfukang Decoction” alone or combined with chemotherapy could down-regulate the transcription and expression of the multidrug resistance gene remarkblely, comparing with a control group (P<0.05) Conclusion: “Jinfukang Decoction” can significantly inhibit the proliferation f the Sca-1+ Lewis lung cancer cell by decreasing the expression of multidrug resistance protein ABCG2.关键词：“Jinfukang Decoction”;Sca-1;+;Lewis lung cancer cell;multidrug resistance ABCG2
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发布时间：2022-08-31 - 摘要：Objective: To observe the anti-inflammatory effect of electroacupuncture on collagen-induced arthritis in rats and to explore the molecular mechanisms of vasoactive intestinal peptide (VIP) in mediating electroacupuncture Methods: Fifty male Sprague Dawley rats were randomly divided into five groups, with 10 rats in each group.Except for the normal saline (NS) group and electroacupuncture group, CIA rat models were established by collagen II.CIA models were induced by collagen type II.Normal saline group and model group were not intervened.Electroacupuncture group and electroacupuncture plus VIP receptor antagonist group, and electroacupuncture plus normal saline group were treated with electroacupuncture at Zusanli (ST-36) and Xuanzhong (GB-39).VIP receptor antagonist was injected before electroacupuncture three times a week, for 4 weeks.Scores of arthritis indexes were recorded during the electroacupuncture intervened period.The pathologic condition of synovial tissues was observed by HE.Expression of VIP was observed by immunohistochemical method, and expressions of serum VIP, IFN-γ and IL-4 were detected by ELISA Results: After intervention, the arthritis scores in electroacupuncture group were lower than that of the model group and electroacupuncture plus VIP receptor antagonist group.H Results: showed that there were inflammatory cells infiltration and fibroblasts proliferation in electroacupuncture group, and were lower than that of the model group.Immunohistochemisty showed that the VIP expression on synovial tissues in electroacupuncture group was significant higher than that of the model group, electroacupuncture plus VIP receptor antagonist group.Expression of VIP and IL-4 in electroacupuncture group were higher than that of the model group and electroacupuncture plus VIP receptor antagonist group (P<0.05, P<0.01); IFN-γ expression in the electroacupuncture group was lower than that of the model group and electroacupuncture plus VIP receptor antagonist group (P<0.05) Conclusion: Electro-acupuncture on Zusanli (ST-36) and Xuanzhong (GB-39) shows significant inhibition role of arthritis in CIA rats.Its mechanism may be associated with up-regulating the IL-4 expression and down-regulating the IFN-γ expression.
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发布时间：2022-08-31 - 摘要：Objective: To observe the mechanism of “Compound Buffalo Horns Granules” in treating acute gouty arthritis.Methods Forty Wister rats were randomized into normal group, model group, Chinese medicine group and western medicine group.Model of acute gouty arthritis was induced with the injection of MSU into rats' ankle joint cavity.Normal group was injected with the same amount of 0.9%NaCl solution.Four hours after injection, buffalo horns group, colchicine group were given corresponding medicines for 3 days, while 0.9% NaCl was used to normal group and model group, once a day, with the course of 3 days.Rats were executed to take serum and ankle synovial tissue, and measured the ankle circumference.The activity of NF-kappa B was measured by electrophoretic mobility shift assay (EMSA).Cytokine protein and gene expressions including TNF-a, IL-8 in arthritic synovium of rats were determined respectively by Western blot assay, reverse transcription polymerase chain reaction (RT-PCR).Results Compared with the normal group, the ankle swelling, activity of NF-kappa B, TNF-аlevels, and expression of IL-8 in synovial tissue of the model group were increased markedly (P<0.01).Compared with the model group, the ankle swelling was alleviated, activity of NF-kappa B, the expressions of TNF-а and IL-8 were inhibited in the Chinese medicine group after treated with “Compound Buffalo Horns Granules” (P<0.05, P<0.01).Conclusion “Compound Buffalo Horns Granules” is effective to treat acute gouty arthritis in rats.Its mechanism may be associated with the inhibitory effect on NF-kappa B activity and down-regulatory effect on TNF-α and IL-8 expression.关键词：acute gouty arthritis;“Compound Buffalo Horns Granules”;NF-kappa B activity;TNF-α;IL-8
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发布时间：2022-08-31 - 摘要：Objective: To observe the effect of Radix Ginseng and Radix Aconiti Lateralis Preparata on hemorheology and cognitive ability in rats with myocardial ischemia of the blood stasis pattern.Methods Sixty SD rats were randomly divided into six groups:blank control group, model group, intraperitoneal “Shenfu Injection” group, oral “Shenfu Injection” group, high dose of “Shenfu Decoction” group, low dose of “Shenfu Decoction” group, with 10 rats in each group.Except for blank group, the rat models with myocardial ischemia were established.Each group was treated with corresponding measurements.The viscosity, blood cell parameters (MCV, RDW-CV, MPV and PDW) and hemorheologic indicators were observed.The cognitive ability in each group was detected.Results ① Compared with the blank group, there were significant differences in the ECG,blood cell parameters, blood viscosity in the model group (P<0.05), which indicated that the blood stasis models were established successfully.② Compared with the model group, the ST amplitude, low, medium and high shearing rates, value of MCV, RDW-CV and MPV and error of step-down test were decreased significantly (P<0.05); the PDW value and blood viscosity in injection group and administration group were decreased (P<0.05); the latent time in the in injection group, administration group and high dose group were increased (P<0.05).there were significant differences in the ST amplitude, blood viscosity, blood cell parameters (MCV, RDW-CV, MPV), sedimentation rate and error of step-down test between the injection group and low dose of “Shenfu Decoction” group (P<0.05).No statistical significance was found in all indicators of the “Shenfu Injection” groups (P>0.05), which indicated that the clinical efficacy of the two groups were similar.③ Correlation analysis on the resultes of the hemorheology and behavior indicators showed that there was correlation between hemorheology and cognitive competence.Conclusion Combination of Radix Ginseng and Radix Aconiti Lateralis Preparata can improve the cognitive competence by improving the property of hemorheology.关键词：“Shenfu Decoction”;blood stasis due to cold stagnation;myocardial ischemia;cognitive competence
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发布时间：2022-08-31 -
Effect of “Tongjie Oral Solution” on IL-6 and TNF-α in rats with multiple organ dysfunction syndrome
摘要：Objective: To investigate the effect “Tongjie Oral Solution” on IL-6 and TNF-α in serum and the ileum of rats with multiple organ dysfunction syndrome (MODS).Methods Fourty-eight male SD rats were randomly divided into 6 groups:control group, model group, positive control group, low dose treatment group, medium dose treatment group and high dose treatment group, with 8 rats in each group.Intragastric administration in advance, 2 days later, intravenous inject Lipopolysaccharide (LPS) of 8mg/kg to build rat models.The vital signs such as electrocardiogram, temperature, breathing extent and respiratory rate; serum indexes such as AST, ALT, CK and Cr; levels of IL-6 and TNF-αin the serum and ileum were detected.Results There were significant differences in the heart rate, temperature, respiratory rate, serum indexes (contents of AST, ALT, CK and Cr in the serum), and contents of TNF-α and IL-6 between the blank group and model group (P＜0.05, P＜0.01).There were the significant differences in the heart rate and temperature between the model group and positive control group (P<0.05); There were the significant difference in the heart rate among the low-, medium- and high-dose treatment groups (P<0.05, P<0.01). There were significant differences in the respiratory rate, serum indexes and IL-6 level in the ileum between the model group and positive control group (P<0.05, P<0.01); there were significant differences in the respiratory rate, serum indexes, TNF-α level and IL-6 level in the serum and ileum between the model group and high-dose treatment group (P<0.05, P<0.01); there were significant differences in the serum indexes, IL-6 in the serum and ileum between the model group and medium-dose treatment group (P＜0.05, P＜0.01); There was a significant difference in the Cr level between the model group and low-dose treatment group (P<0.01).There was a significant difference in the levels of ALT, AST, TNF-α and IL-6 in the serum and IL-6 in the ileum between the low and high-dose treatment groups, and there was a significant difference in the ALT level between the low and medium-dose treatment groups (P＜0.05, P＜0.01).There were significant differences in the contents of AST and ALT bwteen the positive control group and low-dose treatment group, and with significant differences in the IL-6 of the serum and ileum between the positive control group and high-dose treatment group (P＜0.05, P＜0.01).Conclusion “Tongjie Oral Solution” can effectively reduce the levels of IL-6 and TNF-α in both serum and ileum of rats with MODS reduced by lipopolysaccharide.The curative effect was markedly coincident with the dosage of the solution.关键词：“Tongjie Oral Solution”;multiple organ dysfunction syndrome (MODS);IL-6;TNF-α- 5
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发布时间：2022-08-31 - 摘要：Objective: To study the optimum conditions of prepares rare ginsenoside Rk1 and Rg5 by high temperature and high pressure technique (HTHPT).Methods HTHPT was used to prepare rare ginsenoside from P.ginseng.The optimum extracting process was selected by the orthogonal test.The rare ginsenoside Rk1 and Rg5 were determined by HPLC.Results The optimum condition of HTHPT was as follows:the pressure was 125 MPa, the temperature was 120 ℃ the solvent was 50% ethanol, formic acid concentration was 0.05%, reaction time was 2h.Conclusion This preparation technology is valid and feasible.关键词：Panax ginseng C.A.Meyer;ginsenoside Rk;1;ginsenoside Rg;5;orthogonal design;LC-MS analysis
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发布时间：2022-08-31 - 摘要：This paper reviews the progress on treatment of epileptic with ganoderma.Ganoderma contains rich amino acids and microelements.It plays its anti-epileptic effect by regulating immune, antioxidant, scavenging free radical, inhibiting apoptosis, reinforcement learning ability and nourishing nerves.关键词：ganoderma;epileptic;antiepileptic drug
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发布时间：2022-08-31 - 摘要：This paper reviews the research progress on the constitutions and differentiation of the chronic kidney diseases in TCM.It is found that chronic kidney diseases are characterized by qi deficiency, and the constitutions have correlation with the protopathy, pathological patterns and laboratory indexes.Research on characteristics of constitution supplies references for the treatment and prevention of chronic kidney diseases.关键词：chronic kidney disease;constitution in TCM;review
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发布时间：2022-08-31
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