DENG Jianqing,LI Qizhong.Li Qizhong's experience in treating emotional disorders with modified Sini San[J].Shanghai Journal of Traditional Chinese Medicine,2026,60(2):44-48.
DENG Jianqing,LI Qizhong.Li Qizhong's experience in treating emotional disorders with modified Sini San[J].Shanghai Journal of Traditional Chinese Medicine,2026,60(2):44-48. DOI: 10.16305/j.1007-1334.2026.z20250505002.
Li Qizhong's experience in treating emotional disorders with modified Sini San
This paper presents Professor Li Qizhong's clinical experience in treating emotional disorders with modified Sini San. The dialectical viewpoint of "biphasic pathogenesis and the mutual interaction between body and mind" is proposed, suggesting that emotional disorders involve a pathogenesis where "emotional depression causes disease" and "disease causes emotional depression" mutually influencing each other. Therefore, liver qi depression is identified as the key principle, with the middle energizer serving as the pivot, and the core pathogenesis is the depression and stagnation of qi movement. Clinical practice is based on the formula Sini San, integrating three differentiation strategies: "body differentiation, syndrome differentiation, and disease differentiation". Professor Li adheres to the compatibility principle of "dispersing without depleting, and harmonizing without stagnation", emphasizing the combination of compound formulas. Additionally, psychological counseling is incorporated, resulting in significant clinical efficacy and providing new ideas for the treatment of emotional diseases. Two clinical cases are presented for reference.
SANTOSA A , ROSENGREN A , RAMASUNDARAHETTIGE C , et al . Psychosocial risk factors and cardiovascular disease and death in a population based cohort from 21 low-, middle-, and high-income countries [J]. JAMA Netw Open , 2021 , 4 ( 12 ): e2138920 .
CAO L , LIU X , LIN E J , et al . Environmental and genetic activation of a brain-adipocyte BDNF/leptin axis causes cancer remission and inhibition [J]. Cell , 2010 , 142 ( 1 ): 52 - 64 .
KIM S H , HAN J , SEOG D H , et al . Antidepressant effect of Chaihu-Shugan-San extract and its constituents in rat models of depression [J]. Life Sci , 2005 , 76 ( 11 ): 1297 - 1306 .
LAMERS F , MILANESCHI Y , SMIT J H , et al . Longitudinal association between depression and inflammatory markers:Results from the netherlands study of depression and anxiety [J]. Biol Psychiatry , 2019 , 85 ( 10 ): 829 - 837 .