Exploring traditional Chinese medicine prevention and treatment of adverse pregnancy outcomes caused by hypercoagulability in PCOS from perspective of "preventive treatment"

YU Shengyun; YANG Bingyi; JIANG Hang; YIN Xiuqi

doi:10.16305/j.1007-1334.2025.z20240630010

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Exploring traditional Chinese medicine prevention and treatment of adverse pregnancy outcomes caused by hypercoagulability in PCOS from perspective of "preventive treatment"

更新时间：2025-06-27

- Exploring traditional Chinese medicine prevention and treatment of adverse pregnancy outcomes caused by hypercoagulability in PCOS from perspective of "preventive treatment"
- Shanghai Journal of Traditional Chinese Medicine Vol. 59, Issue 7, Pages: 70-74(2025)
- 作者机构：
  
  上海中医药大学附属曙光医院（上海 201203）
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2025.z20240630010
  CLC：
- Received：30 June 2024，
  
  Published：10 July 2025
- 稿件说明：
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于晟贇,杨冰祎,江杭,等.从“治未病”思想探讨PCOS高凝状态所致不良妊娠结局的中医防治[J].上海中医药杂志,2025,59(7):70-74.

YU Shengyun,YANG Bingyi,JIANG Hang,et al.Exploring traditional Chinese medicine prevention and treatment of adverse pregnancy outcomes caused by hypercoagulability in PCOS from perspective of "preventive treatment"[J].Shanghai Journal of Traditional Chinese Medicine,2025,59(7):70-74.
于晟贇,杨冰祎,江杭,等.从“治未病”思想探讨PCOS高凝状态所致不良妊娠结局的中医防治[J].上海中医药杂志,2025,59(7):70-74. DOI： 10.16305/j.1007-1334.2025.z20240630010.

YU Shengyun,YANG Bingyi,JIANG Hang,et al.Exploring traditional Chinese medicine prevention and treatment of adverse pregnancy outcomes caused by hypercoagulability in PCOS from perspective of "preventive treatment"[J].Shanghai Journal of Traditional Chinese Medicine,2025,59(7):70-74. DOI： 10.16305/j.1007-1334.2025.z20240630010.

摘要

多囊卵巢综合征（PCOS）是一种常见的生殖内分泌代谢疾病，易合并胰岛素抵抗和代谢紊乱，增加不良妊娠结局的风险。其发病机制尚不明确，或与高凝状态相关。PCOS高凝状态所致不良妊娠结局的中医核心病机为肾元亏损、气滞血瘀，治则宜遵补肾培元之大法，重视气血宣通畅达。基于中医“治未病”思想，对PCOS高凝状态所致不良妊娠结局应分时而治，即孕前调经、预培其损，孕后活血、有故无殒。并附验案1则。

Abstract

Polycystic ovary syndrome （PCOS） is a common reproductive endocrinological and metabolic disorder， often associated with insulin resistance and metabolic abnormalities， which increase the risk of adverse pregnancy outcomes. However， the pathogenesis remains unclear but may be linked to a hypercoagulable state. In traditional Chinese medicine （TCM）， the core pathogenesis of adverse pregnancy outcomes due to the hypercoagulability in PCOS is related to kidney essence deficiency， and qi stagnation with blood stasis. Treatment principles should focus on tonifying the kidneys and cultivating the essence， with an emphasis on ensuring smooth and unobstructed flow of qi and blood. Therefore， adverse pregnancy outcomes resulting from hypercoagulability in PCOS should be managed in stages， following the TCM principle of "preventive treatment". Preconception treatment should regulate the menstrual cycle and cultivate in advance to prevent potential damage， while post-conception treatment should focus on invigorating blood circulation and ensuring pregnancy preservation. A clinical case is presented for reference.

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references

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