Objective

2

To analyze the pulse characteristic parameters and the distribution of traditional Chinese medicine （TCM） syndromes in patients after colorectal cancer （CRC） surgery， and to explore the relationship between pulse characteristic parameters and different TCM syndromes， providing a reference for intelligent diagnosis and syndrome differentiation of postoperative CRC patients.

Methods

2

Eighty-three postoperative CRC patients （case group） and twenty healthy individuals （normal group） were selected. Patients in the case group were differentiated according to TCM syndromes. Pulse information of all participants was collected using a SmartMX-I type pulse analyzer， and pulse characteristic parameters of postoperative CRC patients were analyzed with the help of a pulse analysis system. Differences in pulse parameters among postoperative CRC patients with different TCM syndromes were compared.

Results

2

①Among the 83 postoperative CRC patients， there were 22 cases of spleen-kidney yang deficiency syndrome， 12 case

s of liver-kidney yin deficiency syndrome， 6 cases of qi and blood deficiency syndrome， 24 cases of damp-heat accumulation syndrome， and 19 cases of stasis-toxin internal accumulation syndrome. ② In the case group， right pulse H1， T5， and T were lower than those in the normal group （

P

<

0.05）， while T1， H3/H1， T1/T， and W/T were higher than those in the normal group （

P

<

0.05）. On the left pulse， H1 and T were also lower than those in the normal group （

P

<

0.05）， with H4， T1， H3/H1， T1/T， and W/T being higher than those in the normal group （

P

<

0.05）. ③Patients with spleen-kidney yang deficiency syndrome and qi and blood deficiency syndrome showed lower H1 in both hands （

P

<

0.05） and lower right pulse W/T （

P

<

0.05） than patients with the other three TCM syndromes. Patients with stasis-toxin internal accumulation syndrome had higher right pulse H3 and W （

P

<

0.05）， higher left pulse H4， W， and H3/H1 （

P

<

0.05） than patients with the other four TCM syndromes， and higher left pulse W/T than patients with spleen-kidney yang deficiency syndrome and those with qi and blood deficiency syndrome （

P

<

0.05）. Patients with damp-heat accumulation syndrome had lower right pulse T1 than those with spleen-kidney yang deficiency syndrome and qi and blood deficiency syndrome （

P

<

0.05）， and lower T than patients with the other four TCM syndromes （

P

<

0.05）. Patients with qi and blood deficiency syndrome had higher right pulse T5 than those with damp-heat accumulation syndrome （

P

<

0.05）， and lower right pulse T1/T than those with damp-heat accumulation syndrome and stasis-toxin internal accumulation syndrome （

P

<

0.05）. Patients with spleen-kidney yang deficiency syndrome had higher left pulse T1 than those with liver-kidney yin deficiency syndrome， damp-heat accumulation syndrome， and stasis-toxin

internal accumulation syndrome （

P

<

0.05）.

Conclusions

2

Pulse parameters in postoperative CRC patients showed characteristic changes and could provide a reference for intelligent diagnosis and syndrome differentiation for postoperative CRC patients. H1 assisted in diagnosing spleen-kidney yang deficiency syndrome and qi and blood deficiency syndrome， T assisted in diagnosing damp-heat accumulation syndrome， and W/T along with H3/H1 assisted in diagnosing stasis-toxin internal accumulation syndrome.