Exploring feasibility of strengthening spleen and nourishing kidney method in regulating intestinal microflora in treatment of systemic lupus erythematosus based on "kidney‑spleen‑intestine axis" theory
|更新时间:2024-12-23
|
Exploring feasibility of strengthening spleen and nourishing kidney method in regulating intestinal microflora in treatment of systemic lupus erythematosus based on "kidney‑spleen‑intestine axis" theory
Shanghai Journal of Traditional Chinese MedicineVol. 58, Issue 12, Pages: 52-55(2024)
QIAN Ai,HUANG Chuanbing,ZHU Yawen,et al.Exploring feasibility of strengthening spleen and nourishing kidney method in regulating intestinal microflora in treatment of systemic lupus erythematosus based on "kidney‑spleen‑intestine axis" theory[J].Shanghai Journal of Traditional Chinese Medicine,2024,58(12):52-55.
QIAN Ai,HUANG Chuanbing,ZHU Yawen,et al.Exploring feasibility of strengthening spleen and nourishing kidney method in regulating intestinal microflora in treatment of systemic lupus erythematosus based on "kidney‑spleen‑intestine axis" theory[J].Shanghai Journal of Traditional Chinese Medicine,2024,58(12):52-55. DOI: 10.16305/j.1007-1334.2024.z20240621009.
Exploring feasibility of strengthening spleen and nourishing kidney method in regulating intestinal microflora in treatment of systemic lupus erythematosus based on "kidney‑spleen‑intestine axis" theory
Starting from the influence of gut microbiota on the pathogenesis of systemic lupus erythematosus (SLE), it is speculated that guided by the theory of "kidney-spleen-intestine axis", the use of "based on spleen and kidney, strengthening the foundation and nourishing primordial qi" and "strengthening the spleen and nourishing the kidneys, clearing the intestines and eliminating evil" methods can regulate gut microbiota to restore body balance and delay the development of SLE.
关键词
系统性红斑狼疮肾-脾-肠轴肠道菌群健脾滋肾法中医药疗法
Keywords
systemic lupus erythematosuskidney-spleen-intestine axisgut microbiotamethod of strengthening the spleen and nourishing the kidneystraditional Chinese medicine therapy
references
WOPEREIS H, SIM K, SHAW A, et al. Intestinal microbiota in infants at high risk for allergy: Effects of prebiotics and role in eczema development[J]. J Allergy Clin Immunol, 2018, 141(4): 1334-1342.
MEI L, YANG Z, ZHANG X, et al. Sustained drug treatment alters the gut microbiota in rheumatoid arthritis[J]. Front Immunol, 2021, 12: 704089.
RAHBAR SAADAT Y, HEJAZIAN M, BASTAMI M, et al.The role of microbiota in the pathogenesis of lupus: Dose it impact lupus nephritis?[J]. Pharmacol Res, 2019, 139: 191-198.
ZHANG L, QING P, YANG H, et al. Gut microbiome and metabolites in systemic lupus erythematosus: Link, mechanisms and intervention[J]. Front Immunol, 2021, 12: 686501.
PAN Q, GUO F, HUANG Y, et al. Gut microbiota dysbiosis in systemic lupus erythematosus: Novel insights into mechanisms and promising therapeutic strategies[J]. Front Immunol, 2021, 12: 799788.
EVENEPOEL P, POESEN R, MEIJERS B. The gut-kidney axis[J]. Pediatr Nephrol, 2017, 32(11): 2005-2014.
MEIJERS B K, EVENEPOEL P. The gut-kidney axis:indoxyl sulfate, p-cresyl sulfate and CRF progression[J]. Nephrol Dial Transplant, 2011, 26(3): 759-761.
CHEN Y, CHEN D, CHEN L, et al. Microbiome-metabolome reveals the contribution of gut-kidney axis on kidney disease[J]. J Transl Med, 2019, 17(1): 5.
LAU W, CHANG Y, VAZIRI N. The consequences of altered microbiota in immune-related chronic kidney disease[J]. Nephrol Dial Transplant, 2021, 36(10): 1791-1798.
RITZ E.Intestinal-renal syndrome:mirage or reality?[J]. Blood Purif, 2011, 31(1-3): 70-76.
CARSETTI R, DI SABATINO A, ROSADO M, et al. Lack of gut secretory immunoglobulin a in memory B-Cell dysfunction-associated disorders: A possible gut-spleen axis[J]. Front Immunol, 2020, 10: 2937.
GAO Y, KANG K, LIU Y, et al. Mechanisms of renal-splenic axis involvement in acute kidney injury mediated by the α7nAChR-NF-κB signaling pathway[J]. Inflammation, 2021, 44(2): 746-757.