WANG Peiji,ZHOU Xiaojie,SANG Xisheng.Research progress on active ingredients and mechanisms of hepatoprotective effect of oysters[J].Shanghai Journal of Traditional Chinese Medicine,2023,57(8):33-37.
WANG Peiji,ZHOU Xiaojie,SANG Xisheng.Research progress on active ingredients and mechanisms of hepatoprotective effect of oysters[J].Shanghai Journal of Traditional Chinese Medicine,2023,57(8):33-37. DOI: 10.16305/j.1007-1334.2023.2304001.
Research progress on active ingredients and mechanisms of hepatoprotective effect of oysters
This article reviews the research progress on the active ingredients and mechanisms of hepatoprotective effects of oysters. The active ingredients of hepatoprotective effect of oyster soft tissue mainly include polysaccharide, taurine, protein (active peptide) and microelement, etc. The mechanisms of action are related to anti-inflammation, antioxidation, improvement of lipid metabolism, and regulation of gut microbiota, etc.
关键词
牡蛎肝脏疾病酒精性肝病自身免疫性肝病有效成分作用机制研究进展
Keywords
oysterliver diseasesalcoholic liver diseaseautoimmune liver diseaseactive ingredientmechanism of actionresearch progress
SHI X, MA H, TONG C, et al. Hepatoprotective effect of a polysaccharide from Crassostrea gigas on acute and chronic models of liver injury[J]. Int J Biol Macromol, 2015, 78: 142-148.
MURATA Y, TOUHATA K, MIWA R. Correlation of extractive components and body index with taste in oyster Crassostrea gigas brands[J]. Fisheries Sci, 2020, 86(3): 561-572.
TANAKA K, NISHIZONO S, KUGINO K, et al. Effects of dietary oyster extract on lipid metabolism, blood pressure, and blood glucose in SD rats, hypertensive rats, and diabetic rats[J]. Biosci Biotechnol Biochem, 2006, 70(2): 462-470.
TRAN N K, KWON J E, KANG S C, et al. Crassaostrea gigas oyster shell extract inhibits lipogenesis via suppression of serine palmitoyltransferase[J]. Nat Prod Commun, 2015, 10(2): 349-352.
YAO Z, LIANG G, LV Z L, et al. Taurine reduces liver damage in non-alcoholic fatty liver disease model in rats by down-regulating IL-9 and tumor growth factor TGF-β[J]. Bull Exp Biol Med, 2021,171(5): 638-643.
TANG R, YANG Q, LIN S, et al. Preventive or curative administration of taurine regulates lipid metabolism in the liver of rats with alcoholic liver disease[J]. Adv Exp Med Biol, 2019, 1155: 119-131.
DE CASTRO R J S, SATO H H. Biologically active peptides: processes for their generation, purification and identification and applications as natural additives in the food and pharmaceutical industries[J]. Food Res Int, 2015, 74: 185-198.
WANG X, YU H, XING R, et al. Hepatoprotective effect of oyster peptide on alcohol-induced liver disease in mice[J]. Int J Mol Sci, 2022, 23(15): 8081.
SUMAILY K M. The roles and pathogenesis mechanisms of a number of micronutrients in the prevention and/or treatment of chronic hepatitis, COVID-19 and Type-2 diabetes mellitus[J]. Nutrients, 2022, 14(13): 2632.
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