Objective,2,Through the study on the treatment of limb arthralgia with Aconiti Lateralis Radix Praeparata in the Tang and Song dynasties， the dosage， preparation and matching methods of Aconiti Lateralis Radix Praeparata were summarized， which could guide modern clinical applications.,Methods,2,Through sorting the prescriptions for the treatment of limb arthralgia in the Tang and Song dynasties， and selecting prescriptions that contained Aconiti Lateralis Radix Praeparata， the use range， dose， preparation and synergy of Aconiti Lateralis Radix Praeparata were analyzed through dosage conversion between ancient and modern times.,Results,2,In the Tang and Song dynasties， Aconiti Lateralis Radix Praeparata had a wide range of applications， not only for the bi caused by cold evil， but also for the bi caused by hot evil through drug synergy. Among the three kinds of bi， such as painful bi， migratory bi and stationary bi， Aconiti Lateralis Radix Praeparata was most commonly used for painful bi. In the Tang and Song dynasties， the common dosage of Aconiti Lateralis Radix Praeparata in decoction， pill and powder was similar. The dosage span of decoction was the most， and the maximum dosage was 160 g. The dosage of Aconiti Lateralis Radix Praeparata in powder in Song Dynasty was much lower than that in Tang Dynasty.There was no special decoction method for Aconiti Lateralis Radix Praeparata in limb arthralgia. Aconiti Lateralis Radix and Praeparata-Saposhnikoviae Radix was a common detoxifying drug pair.,Conclusions,2,Pain was the opportunity to use Aconiti Lateralis Radix Praeparata. The method of clearing heat could be added accordingly depending on incorporating thermography. In small and medium dosage， conventional decoction might be more effective in anti-inflammatory and analgesic effects without poisoning. Aconiti Lateralis Radix Praeparata and Praeparata-Saposhnikoviae Radix were compatible for treating bi， which could both enhance the effect and reduce the toxicity. In brief， the experience of Aconiti Lateralis Radix Praeparata in the treatment of limb arthralgia in the Tang and Song dynasties had important reference value for the clinical treatment of rheumatology in traditional Chinese medicine.