Wang Lingtai’s experience in differentiating and treating chronic liver diseases based on the theory of “Danggui activating blood and Danshen harmonizing blood”

LI Yuyao; WANG Lingtai; GAO Yueqiu; YU Zhuo

doi:10.16305/j.1007-1334.2023.2209039

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Wang Lingtai’s experience in differentiating and treating chronic liver diseases based on the theory of “Danggui activating blood and Danshen harmonizing blood”

更新时间：2023-05-16

- Wang Lingtai’s experience in differentiating and treating chronic liver diseases based on the theory of “Danggui activating blood and Danshen harmonizing blood”
- Shanghai Journal of Traditional Chinese Medicine Vol. 57, Issue 5, Pages: 8-11(2023)
- 作者机构：
  
  1.上海中医药大学附属曙光医院（上海 201203）
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2023.2209039
  CLC：
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李玉瑶,王灵台,高月求,等.王灵台基于“当归活血，丹参和血”理论辨治慢性肝病经验[J].上海中医药杂志,2023,57(5):8-11.

LI Yuyao,WANG Lingtai,GAO Yueqiu,et al.Wang Lingtai’s experience in differentiating and treating chronic liver diseases based on the theory of “Danggui activating blood and Danshen harmonizing blood”[J].Shanghai Journal of Traditional Chinese Medicine,2023,57(5):8-11.
李玉瑶,王灵台,高月求,等.王灵台基于“当归活血，丹参和血”理论辨治慢性肝病经验[J].上海中医药杂志,2023,57(5):8-11. DOI： 10.16305/j.1007-1334.2023.2209039.

LI Yuyao,WANG Lingtai,GAO Yueqiu,et al.Wang Lingtai’s experience in differentiating and treating chronic liver diseases based on the theory of “Danggui activating blood and Danshen harmonizing blood”[J].Shanghai Journal of Traditional Chinese Medicine,2023,57(5):8-11. DOI： 10.16305/j.1007-1334.2023.2209039.

摘要

总结王灵台教授从“当归活血，丹参和血”理论辨治慢性肝病经验。认为慢性肝病之发，始之于气，久则及血，终致气血瘀滞；慢性肝病之治，当扶正祛邪，调和气机，从瘀论治。活血化瘀力度之轻重当随病情辨证综合考虑，宜灵活运用活血之当归、和血之丹参，并强调因人而异，此为治疗之关键所在。

Abstract

This paper aims to summarize Professor Wang Lingtai’s experience in differentiating and treating chronic liver diseases based on the theory of “Danggui （Angelicae Sinensis Radix） activating blood and Danshen （Salviae Miltiorrhizae Radix et Rhizoma） harmonizing blood”. It is believed that the onset of chronic liver diseases starts with qi stagnation， gradually affects the blood， and eventually leads to stagnation of qi and blood. When it comes to the treatment of chronic liver diseases， it is necessary to strengthen the healthy qi and eliminate pathogenic factors， regulate the movement of qi and focus on the treatment of stasis. The choice of herbs for activating blood and resolving stasis should be made depending on the comprehensive consideration of disease condition and syndrome differentiation. It is appropriate to flexibly use Angelicae Sinensis Radix to activate blood and Salviae Miltiorrhizae Radix et Rhizoma to harmonize blood. It is also highlighted that individualized treatment is the key to treat chronic liver diseases .

关键词

慢性肝病当归丹参活血化瘀名医经验中医药疗法

Keywords

chronic liver diseaseDanggui（Angelicae Sinensis Radix）Danshen（Salviae Miltiorrhizae Radix et Rhizoma）activating blood and resolving stasisfamous doctor’s experiencetraditional Chinese medicine therapy

references

阿比丹·拜合提亚尔，郭津生. 慢性肝病病因特异与非特异的肝细胞肝癌发生机制［J］. 西南医科大学学报，2021， 44（6）： 593-600.

朱永芬，王进，方家追，等. 慢性乙型肝炎及非酒精性脂肪性肝炎患者肝脏病理特征分析［J］. 中西医结合肝病杂志，2019， 29（6）： 505-506.

郭甘霖，牛坤旭，马天越，等. 张锡纯运用当归经验探析［J］. 浙江中医药大学学报，2021， 45（8）： 934-938.

董帅，王辉，谢治深. 丹参功用本草考证及现代药理认识［J］. 辽宁中医药大学学报，2019， 21（11）： 152-155.

李慧芸，童元元，李宗友. 《太平圣惠方》含丹参方用药规律研究［J］. 中国中医药图书情报杂志，2022， 46（2）： 15-21.

宋东红. 运用国医大师孙光荣参、芪-丹参药组结合和中运脾理论的实践［J］. 光明中医，2021， 36（23）： 3968-3972.

房昉，温伟波. 基于《中华医典》探讨丹参对肝病的治疗作用［J］. 云南中医中药杂志，2022， 43（3）： 18-27.

CAO P， SUN J， SULLIVAN M A， et al. Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury and cell death by suppressing oxidative stress and hepatic apoptosis in vivo and in vitro［J］. Int J Biol Macromol， 2018， 111： 1133-1139.

WANG K， WANG J， SONG M， et al. Angelica sinensis polysaccharide attenuates CCl（4）-induced liver fibrosis via the IL-22/STAT3 pathway［J］. Int J Biol Macromol， 2020， 162： 273-283.

LI C， LIU S， ZHENG J， et al. Angelica sinensis polysaccharide （ASP） attenuates diosbulbin-B （DB）-induced hepatotoxicity through activating the MEK/ERK pathway［J］. Bioengineered， 2021， 12（1）： 3516-3524.

彭渊，马园园，黄恺，等. 丹参抑制NLRP3炎症小体减轻胆汁淤积性肝损伤［J］. 上海中医药大学学报，2019， 33（1）： 66-70.

NAGAPPAN A， KIM J H， JUNG D Y， et al. Cryptotanshinone from the Salvia miltiorrhiza bunge attenuates ethanol-induced liver injury by activation of AMPK/SIRT1 and Nrf2 signaling pathways ［J］. Int J Mol Sci， 2019， 21（1）：265.

WU C T， DENG J S， HUANG W C， et al. Salvianolic acid C against acetaminophen-induced acute liver injury by attenuating inflammation， oxidative stress， and apoptosis through inhibition of the Keap1/Nrf2/HO-1 signaling ［J］. Oxid Med Cell Longev， 2019， 2019： 9056845.

陶慧娟，乐世俊，唐于平，等. 基于主成分分析和多指标综合指数法研究丹参-三七药对活血化瘀作用量效关系［J］. 中国新药杂志，2019， 28（17）： 2141-2147.

霍苏，崔鹤蓉，顾昱昊，等. 基于网络药理学探究丹参治疗慢性肝炎的作用机制［J］. 世界中医药，2021， 16（20）： 2992-2998.

CAO T， LU Y， ZHU M， et al. Effects of Salvia miltiorrhiza and Radix astragali on the TGF-β/Smad/Wnt pathway and the pathological process of liver fibrosis in rats［J］. Cell Mol Biol （Noisy-le-grand）， 2020， 66（6）： 46-51.

ZHANG X， ZHANG P， AN L， et al. Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis ［J］. Acta Pharm Sin B， 2020， 10（8）： 1397-1413.

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