Objective,2,To investigate the factors influencing sleep disorders and the distribution characteristics of traditional Chinese medicine （TCM） syndromes in patients with early- or mid-stage Parkinson’s disease （PD）.,Methods,2,Based on the Parkinson’s Disease Sleep Scale （PDSS） score， 87 patients with early- or mid-stage PD were divided into the PD sleep disorder group （,n,=46） and the PD without sleep disorder group （,n,=41）. Baseline data such as gender， age， age of onset， duration of illness， Hoeln-Yahr Stage， and scores of the Unified Parkinson Disease Rating Scale （UPDRS）， Scales for Outcomes in Parkinson’s disease - Autonomic （SCOPA-AUT）， Hamilton Depression Scale （HAMD）， Hamilton Anxiety Scale （HAMA）， Minimum Mental State Examination （MMSE） and the Parkinson’s Disease Questionnaire （PDQ-39） were analyzed and compared between the two groups. All patients with early- or mid-stage PD had TCM syndrome differentiation， the distribution pattern of TCM syndromes were analyzed， and the sleep condition in patients with different TCM syndromes were compared. Linear regression analysis or Logistic regression analysis was used to test for linear trends between the total PDSS score and each variable， and to explore the influencing factors of sleep disorders in early- or mid-stage PD patients.,Results,2,①No statistically significant baseline difference was found between the two groups （,P,>,0.05）. The scores of SCOPA-AUT， HAMA， HAMD， PDQ-39 and subscales of UPDRS （I mentation， behavior and mood， Ⅱ activities of daily living， Ⅲ motor exam） were higher in the PD with sleep disorder group than those in the PD without sleep disorder group （,P,<,0.05）. ②Among the 87 patients with early- or mid-stage PD collected in this study， there were 22 cases with qi and blood deficiency syndrome， 21 cases with qi stagnation and blood stasis syndrome， 15 cases with stirring wind due to phlegm-heat syndrome， and 29 cases with liver and kidney deficiency syndrome. There was a statistically significant difference in the distribution of TCM syndromes between the PD with sleep disorder group and the PD without sleep disorder group （,P,<,0.05）. The most common TCM syndrome in the PD with sleep disorder group was liver and kidney deficiency syndrome （43.50%） while that in the PD without sleep disorder group was qi stagnation and blood stasis syndrome （41.50%）. ③The differences in the total PDSS scores of early- or mid-stage PD patients with different TCM syndrome were statistically significant （,P,<,0.05）， and the total PDSS score in patients with the liver and kidney deficiency syndrome was the lowest. ④The total PDSS score was negatively correlated with age， UPDRS Ⅰ， UPDRS Ⅱ， UPDRS Ⅲ， SCOPA-AUT， HAMA， HAMD and PDQ-39 scores （,r,<,0， ,P,<,0.05）， and UPDRS Ⅰ， UPDRS Ⅱ， SCOPA-AUT， HAMA， HAMD， and PDQ-39 were risk factors （,P,<,0.05）.,Conclusions,2,Older patients with early- or mid-stage PD are more likely to have sleep disorders， more severe motor and autonomic symptoms， as well as anxiety and depression， affecting their quality of life. The most common TCM syndrome of early- or mid-stage PD patients with sleep disorders is liver and kidney deficiency syndrome， and patients with this syndrome have the most serious sleep disorder.