GUO Tingting,JI Bo,LIU Yitian,et al.Data mining⁃based study on application rules of stimulation parameters of electroacupuncture and transcranial electrical stimulation for dementia[J].Shanghai Journal of Traditional Chinese Medicine,2023,57(4):65-71.
GUO Tingting,JI Bo,LIU Yitian,et al.Data mining⁃based study on application rules of stimulation parameters of electroacupuncture and transcranial electrical stimulation for dementia[J].Shanghai Journal of Traditional Chinese Medicine,2023,57(4):65-71. DOI: 10.16305/j.1007-1334.2023.2206085.
Data mining⁃based study on application rules of stimulation parameters of electroacupuncture and transcranial electrical stimulation for dementia
Objective,2,To study the application rules of stimulation parameters of electroacupuncture and transcranial electrical stimulation (TES) for dementia with data mining techniques.,Methods,2,Both Chinese databases including Chinese National Knowledge Infrastructure (CNKI), VIP Database for Chinese Technical Periodicals (VIP), WanFang Data, China Biology Medicine (CBM) and English databases including PubMed, Web of Science, Embase, and Cochrane Library were systematically searched for clinical research literature related to electroacupuncture and TES for dementia which were published from the establishment of databases up to May 2022. The quality of randomized controlled trials in the included literature was assessed using the Cochrane 5.4 risk of bias tool. A database of electrical stimulation parameters was established and data mined using descriptive analysis, association rules, and cluster analysis.,Results,2,①Finally, 175 articles were included, of which 143 were randomized controlled trials, containing data from 179 groups. ②Overall, the frequently used pulse waveforms were continuous wave (57 times, 50.44%) and disperse-dense wave (44 times, 38.94%), and electrical stimulation frequency was 300 to 500 times/min (5.00-8.33 Hz) when using electroacupuncture and TES for dementia. The electrical stimulation intensity of electroacupuncture therapy was often determined by patient tolerance, and a single treatment session was 30 min. The stimulation intensity of TES therapy was 2 mA, and a single treatment session was 20 min. ③The commonly used stimulation parameters of electroacupuncture and TES for vascular dementia (VaD) were consistent with literature data in general, while those for Alzheimer’s disease (AD) were different from literature data: the frequently used pulse waveform was continuous wave, and the electrical stimulation frequency was 10/50 Hz. The electrical stimulation intensity was determined by patient tolerance for electroacupuncture, while that of TES was 2 mA, and a single treatment session often lasted 30 min for both electroacupuncture and TES. ④The most frequently selected acupoints were Baihui (DU20), Sishencong (Ex-HN01), Fengchi (GB20), Shenting (DU24), and Benshen (GB13), and the most frequently selected meridians were Du meridian, gallbladder meridian and stomach meridian. ⑤According to the association rule analysis, for electroacupuncture treatment of dementia, the most frequently used acupoint-pair was Baihui (DU20)-Shenting (DU24), 3-acupoint-combination was Sishencong (Ex-HN01)-Fengchi (GB20)-Baihui (DU20), and 4-acupoint-combination was Baihui (DU20)- Shenting (DU24)- Fengchi (GB20)- Sishencong (Ex-HN01). The cluster analysis also revealed that among the clusters formed by common acupoints, the pair of Fengchi (GB20) and Sishencong (Ex-HN01), and that of Baihui (DU20) and Shenting (DU24) were in two separate clusters.,Conclusions,2,Continuous waves are commonly used at a frequency of 300 to 500 times/min (5.00-8.33 Hz) for electroacupuncture and TES for dementia. The electrical stimulation intensity of electroacupuncture is often determined by the patient tolerance, and a single treatment session lasts 30 min. The electrical stimulation intensity of TES therapy is 2 mA, and a single treatment session is 20 min. The frequently used acupoints for electroacupuncture and TES for dementia are Baihui (DU20), Sishencong (Ex-HN01), Shenting (DU24), and Fengchi (GB20), which were closely compatible with each other.
关键词
痴呆阿尔茨海默病电针经颅电刺激刺激参数中医药疗法
Keywords
dementiaAlzheimer’s diseaseelectroacupuncturetranscranial electrical stimulationstimulation parametertraditional Chinese medicine therapy
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