Objective,2,To investigate the distribution of related symptoms and traditional Chinese medicine （TCM） patterns in women with perimenopausal syndrome.,Methods,2,The data of patients with perimenopausal syndrome were collected with the self-developed menopausal application， and modified Kupperman Index （KI）， menopausal status classifications and TCM syndromes were determined to analyze the distribution of main symptoms， menopausal status and TCM syndromes. The differences in modified KI scores of patients with different TCM syndromes， as well as the differences in age of patients with different menopausal status and TCM syndromes were compared.,Results,2,①A total of 846 valid cases were collected， of which more than half presented with fatigue （95.74%）， mood fluctuation （89.13%）， insomnia （86.05%）， painful intercourse （70.33%）， palpitations （68.91%）， headache （68.91%）， bone and joint pain （65.37%）， depression and suspicion （64.07%）， hot flashes and sweating （63.36%）， and dizziness （62.53%）， and other symptoms. ②The majority of cases collected in our study were mild and moderate， with 296 （34.99%） mild ones and 399 （47.16%） moderate ones. According to the TCM syndrome differentiation， the predominant ones were kidney yin-yang deficiency syndrome （42.67%） and kidney deficiency and liver depression syndrome （32.51%）， and the rest were liver-kidney yin deficiency syndrome （13.59%） and disharmony between heart and kidney syndrome （11.23%）. ③The modified KI scores of patients with different TCM syndromes differed， with the highest scores in patients with kidney deficiency and liver depression syndrome and the lowest scores in patients with liver-kidney yin deficiency syndrome， and the differences were statistically significant （,P<,0.05）. Among the subscales of the modified KI， patients with kidney deficiency and liver depression syndrome had the highest score in the subscale of hot flashes and sweating （,P,<,0.05）； patients with disharmony between heart and kidney syndrome had the highest score in the subscale of insomnia （,P,<,0.05）； and patients with kidney yin-yang deficiency syndrome had the highest score in the subscale of depression and suspicion （,P,<,0.05）. ④Patients with severe menopausal status were the oldest， and the menopausal status grading increased with age （,F,=28.31， ,P,<,0.001）. ⑤Patients with kidney yin-yang deficiency syndrome were the youngest， followed by those with kidney deficiency and liver depression syndrome， liver-kidney yin deficiency syndrome， and disharmony between heart and kidney syndrome （,F,=13.606， ,P,<,0.001）.,Conclusions,2,Fatigue， mood fluctuation， and insomnia are common symptoms in patients with perimenopausal syndrome， and the dominant TCM syndromes are kidney yin-yang deficiency syndrome and kidney deficiency and liver depression syndrome. Patients with kidney deficiency and liver depression syndrome have a relatively more severe menopausal status， and the menopausal status worsens with age.