Objective,2,To observe the effect of regular practice of Kangyi Qiangshen Gong （anti-epidemic and body-strengthening exercise） on the 7-day nucleic acid negative conversion rate and anxiety in patients with mild and asymptomatic infection of the COVID-19 Omicron variant.,Methods,2,A total of 580 patients with mild and asymptomatic infection of COVID-19 Omicron variant were randomly divided into a treatment group （,n,=290） and a control group （,n,=290）. The control group was administered with Jingyin Granules as the basic treatment and daily nucleic acid test， while the treatment group was guided to practice Kangyi Qiangshen Gong regularly besides all the intervention measures in the control group. The interventions in both groups lasted 7 days. Nucleic acid negative conversion rate， hospitalization duration and self-rating anxiety scale （SAS） scores were observed and compared.,Results,2,①During the trial， there were no drop-outs in both groups， and all cases completed the trial. ②There was statistically significant difference in the 7-day nucleic acid negative conversion rate between the two groups， and the treatment group had significantly higher rate than the control group （,P,<,0.05）. ③There was no significant difference in the average length of stay in hospitals between the two groups （,P,>,0.05）. ④After intervention， there was significant difference in the positive rate of anxiety between the two groups （,P,<,0.05）. ⑤There were significant differences in SAS scores between the two groups before and after intervention （,P,<,0.05）； The SAS score of the treatment group was significantly lower than that of the control group after intervention （,P,<,0.05）.,Conclusion,2,Regular practice of Kangyi Qiangshen Gong can increase the nucleic acid negative conversion rate within 7 days in mildly infected and asymptomatic patients with the COVID-19 Omicron variant infection and relieve their anxiety.