Evidence evaluation tool for clinical randomized controlled trials of traditional Chinese medicine based on GRADE System

Wei ZHANG; Lin MA; Hongyong DENG

doi:10.16305/j.1007-1334.2022.2111011

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Evidence evaluation tool for clinical randomized controlled trials of traditional Chinese medicine based on GRADE System

更新时间：2022-07-09

- Evidence evaluation tool for clinical randomized controlled trials of traditional Chinese medicine based on GRADE System
- Shanghai Journal of Traditional Chinese Medicine Vol. 56, Issue 4, Pages: 6-13(2022)
- 作者机构：
  
  1.上海中医药大学科技信息中心（上海 201203）
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2022.2111011
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张薇,马琳,邓宏勇.基于GRADE的中医临床随机对照试验证据评价工具研究[J].上海中医药杂志,2022,56(04):6-13.

ZHANG Wei,MA Lin,DENG Hongyong.Evidence evaluation tool for clinical randomized controlled trials of traditional Chinese medicine based on GRADE System[J].Shanghai Journal of Traditional Chinese Medicine,2022,56(04):6-13.
张薇,马琳,邓宏勇.基于GRADE的中医临床随机对照试验证据评价工具研究[J].上海中医药杂志,2022,56(04):6-13. DOI： 10.16305/j.1007-1334.2022.2111011.

ZHANG Wei,MA Lin,DENG Hongyong.Evidence evaluation tool for clinical randomized controlled trials of traditional Chinese medicine based on GRADE System[J].Shanghai Journal of Traditional Chinese Medicine,2022,56(04):6-13. DOI： 10.16305/j.1007-1334.2022.2111011.

摘要

目的,2,对GRADE体系进行修订，在保留GRADE体系科学性的同时体现中医特色、提高实用性。,方法,2,在文献研究基础上制定改良德尔菲专家调查问卷的初始修订条目，进行两轮专家调查；召开专家共识会议，形成评价工具。,结果,2,共有27位专家完成了两轮对初始修订条目的问卷调查并给出专家意见，5位专家参加了专家共识会议，最终形成了基于GRADE的中医临床适应性和简化性修订的中医临床随机对照试验证据评价工具，内容包含9项修订，涉及高质量证据来源、证据降级因素和升级因素3个方面。,结论,2,通过修订GRADE系统，可以更好地体现并适应中医理论和临床特色，从而提高GRADE在中医临床证据评价中的应用质量。

Abstract

Objective,2,The GRADE system was revised to retain its scientific nature， reflect the characteristics of traditional Chinese medicine （TCM） and improve its practicality.,Methods,2,The initial revised entries of the modified Delphi expert questionnaire were formulated on the basis of literature research， and two rounds of expert surveys were conducted. An expert consensus meeting was held to form an evaluation tool.,Results,2,A total of 27 experts participated in the two rounds of questionnaire surveys on the initial revised entries and provided expert opinions， and 5 experts participated in the expert consensus meeting， who facilitated the formation of ,Evidence⁃Evaluation Tool of Clinical Evidence of Traditional Chinese Medicine Clinical Randomized Controlled Trials Based on GRADE System. ,The evaluation tool simplifies the GRADE system and adapts to the TCM clinical application， and it contains 9 revised items involving high-quality evidence sources， evidence downgrading factors and upgrading factors.,Conclusion,2,After revision， the GRADE system can better embody the theoretical and clinical characteristics of TCM and becomes more adaptable so that it can improve the application quality of GRADE system in the evaluation of TCM clinical evidence.

关键词

中医药学GRADE体系临床疗效评价随机对照试验循证医学专家共识

Keywords

traditional Chinese medicineGRADE systemclinical effect evaluationrandomized controlled trialsevidence-based medicineexpert consensus

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