Objective,2,To explain the “disease-syndrome-pathogenesis-method coherence” rule system and its logical relationships in the revised editions of ,Classification and Codes of Diseases and Patterns of Traditional Chinese Medicine, and ,Clinic Terminology of Traditional Chinese Medical Diagnosis and Treatment, （hereinafter referred to as “the new edition of TCM National Standards”） for the purpose of promoting the soul recasting of contemporary TCM clinics and its return to the academic noumenon and clinical path.,Methods,2,Based on the retrospective literature review of traditional Chinese medicine， terminology and standardology， we adopted computer ontology technology and artificial intelligence to trace the origin of standards， standard knowledge system， standard rule system and TCM disease classification system， organize the concepts of “disease”， “syndrome”， “pathogenesis” and “method”， analyze the academic concepts of “seeking the root of the disease” and “identifying the root of the disease and observing the pathogenesis of the disease”， and present the internal logical relationships of the “disease-syndrome-pathogenesis-method coherence” in the new edition of TCM National Standards with the help of the “TCM National Standard Application Service Platform” （hereinafter referred to as “Standard Platform”）.,Results,2,The new edition of TCM National Standards has defined the connotation and extension of TCM terms such as “disease”， “syndrome”， “pathogenesis” and “method”， etc.， determined the basic rule that must be followed in the TCM clinical diagnosis and treatment to be “seeking the root of the disease， connecting disease differentiation with syndrome differentiation， matching pathogenesis with the syndrome， and prescribing in accordance with the method”. Being the “root” and “soul” of TCM clinical thinking and diagnosis and treatment standard， it is this basic rule that runs through the whole revising process of TCM National Standards. The concept and rule of “disease-syndrome-pathogenesis-method coherence” have also been incorporated into the knowledge system and rule system of the new edition of TCM National Standards.,Conclusion,2,The diagnosis and treatment rule of “disease-syndrome-pathogenesis-method coherence” contained in the new edition of TCM National Standards can be fully demonstrated and widely applied through the Standard Platform. Meanwhile， it can guide TCM clinic practice to follow its own academic and clinical path and standardize its medical activities.