Objective,2,To investigate the clinical effect of Xiaoxuming Decoction combined with conventional therapy on post-stroke upper limb spasticity (wind-phlegm obstructing collaterals syndrome).,Methods,2,Ninety patients with post-stroke upper limb spasticity (wind-phlegm obstructing collaterals syndrome) were randomly divided into control group (,n,=45) and test group (,n,=45). The control group was administered with conventional secondary prophylaxis combined with rehabilitation training, while the test group was administered with Xiaoxuming Decoction besides the treatment measures of the control group. The treatment duration was 12 weeks. The pre- and post-treatment clinical indicators, including surface electromyography (EMG) signals, Modified Ashworth Scale (MAS) scores, Fugl-Meyer Assessment (FMA) scores and Modified Barthel Index (MBI) scores, were compared between the two groups, and the safety was evaluated.,Results,2,①There were 3 drop-out cases in the test group and 1 drop-out case in the control group, and 86 cases completed the trial, including 42 cases in the test group and 44 cases in the control group. ②Intra-group comparison before and after treatment showed that the integrated EMG (IEMG) and root mean square (RMS) values of biceps and triceps decreased in both groups (,P,<,0.05); After treatment, RMS values of biceps and triceps were significantly different between the two groups (,P,<,0.05). ③According to the intra- group comparison of the two groups before and after treatment, the MAS scores of the two groups improved (,P,<,0.05); After treatment, there was a significant difference in the MAS scores between the two groups (,P,<,0.05). ④The scores of FMA and MBI increased after 6 weeks of treatment and after treatment in both groups compared to those before treatment (,P,<,0.05); According to the inter-group comparison after 6 weeks of treatment, the difference in scores of MBI was significant between the groups (,P,<,0.05); After treatment, the scores of FMA and MBI were significantly different between the two groups (,P,<,0.05). ⑤During the trial, no significant adverse reactions were observed in both groups.,Conclusion,2,The combined use of Xiaoxuming Decoction and conventional therapy is effective in treating post-stroke upper limb spasticity (wind-phlegm obstructing collaterals syndrome) by effectively reducing upper limb muscle tension, relieving post-stroke spasticity, and improving daily living ability and motor function.