Clinical observation on Tiaozang Shumi Decoction in the treatment of chronic constipation (deficiency syndrome)

Yibin FAN; Xiaochun FAN; Zhijiu WU; Xuegui TANG

doi:10.16305/j.1007-1334.2021.2008122

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Clinical observation on Tiaozang Shumi Decoction in the treatment of chronic constipation (deficiency syndrome)

更新时间：2022-08-03

- Clinical observation on Tiaozang Shumi Decoction in the treatment of chronic constipation (deficiency syndrome)
- Shanghai Journal of Traditional Chinese Medicine Vol. 55, Issue 2, Pages: 59-62(2021)
- 作者机构：
  
  1.四川省南充市中医医院肛肠科（四川　南充　637000）
  2.四川省南充市中医医院骨科（四川　南充　637000）
  3.川北医学院附属医院肛肠科（四川　南充　637000）
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2021.2008122
  CLC：
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Yibin FAN, Xiaochun FAN, Zhijiu WU, et al. Clinical observation on Tiaozang Shumi Decoction in the treatment of chronic constipation (deficiency syndrome). [J]. Shanghai Journal of Traditional Chinese Medicine 55(2):59-62(2021)
DOI：

Yibin FAN, Xiaochun FAN, Zhijiu WU, et al. Clinical observation on Tiaozang Shumi Decoction in the treatment of chronic constipation (deficiency syndrome). [J]. Shanghai Journal of Traditional Chinese Medicine 55(2):59-62(2021) DOI： 10.16305/j.1007-1334.2021.2008122.

摘要

目的,2,观察调脏舒秘方治疗慢性便秘（虚证）的临床疗效。,方法,2,将254例慢性便秘（虚证）患者随机分为对照组和治疗组，每组127例。对照组予渗透性泻剂（复方聚乙二醇电解质散Ⅳ）治疗，治疗组予调脏舒秘方治疗。两组均连续治疗2周，观察临床疗效，比较便秘主要症状积分、状态-特质焦虑问卷（STAI）评分的变化情况。,结果,2,①治疗组近期疗效、远期疗效均优于对照组（,P,<,0.05）。②治疗后、停药后2周与治疗前组内比较，两组粪便性状、排便费力、每次排便时间、下坠不尽感、排便频率、腹胀评分均降低（,P,<,0.05）；停药后2周与治疗后比较，治疗组便秘各症状评分差异无统计学意义（,P,>,0.05），对照组粪便性状、排便费力、排便时间、排便频率、腹胀评分升高（,P,<,0.05）。治疗后、治疗结束后2周组间比较，治疗组便秘各症状评分低于对照组（,P,<,0.05）。③治疗前后组内比较，两组STAI 中的状态焦虑量表（S-AI）、特质焦虑量表（T-AI）评分均降低（,P,<,0.05）；组间治疗后比较，治疗组S-AI、T-AI评分低于对照组（,P,<,0.05）。④治疗期间，两组患者均未出现明显的不良反应。,结论,2,与复方聚乙二醇电解质散Ⅳ相比，调脏舒秘方治疗慢性便秘（虚证）疗效满意，能更好地改善患者的临床症状及不良心理情绪，且疗效持久，安全性良好。

Abstract

Objective,2,To observe the clinical effect of Tiaozang Shumi Decoction in the treatment of chronic constipation of deficiency syndrome.,Methods,2,Totally 254 patients with chronic constipation of deficiency syndrome were randomly divided into control group (,n,=127) and treatment group (,n,=127). Control group was treated with permeable cathartic (Polyethylene Glycol Electrolytes Powder Ⅳ), and treatment group was treated with Tiaozang Shumi Decoction, and the two groups were continuously treated for 2 weeks. The clinical effect was observed, and scores of the main constipation symptoms and State-Trait Anxiety Inventory (STAI) were compared.,Results,2,①The short-term and long-term effects in the treatment group were superior to those in the control group (,P,<,0.05). ②After treatment and 2 weeks after drug withdrawal, the scores of fecal characteristics, laborious defecation, defecation time, straining at stool and decreased force of urination, defecation frequency and abdominal distension in the two groups were all lower than those before treatment (,P,<,0.05). There were no significant differences in the scores of constipation symptoms in the treatment group 2 weeks after drug withdrawal compared with those after treatment (,P,>,0.05), and the scores of fecal characteristics, laborious defecation, defecation time, straining at stool and decreased force of urination, defecation frequency and abdominal distension in the control group increased (,P,<,0.05). After treatment and 2 weeks after treatment, the scores of constipation symptoms in the treatment group were lower than those in the control group (,P,<,0.05). ③The scores of State Anxiety Inventory (S-AI) and Trait Anxiety Inventory (T-AI) of STAI decreased in both groups after treatment (,P,<,0.05). The scores of S-AI and T-AI in the treatment group were lower than those in the control group after treatment (,P,<,0.05). ④During the treatment, no obvious adverse reactions occurred in both groups.,Conclusion,2,Compared with Polyethylene Glycol Electrolytes Powder Ⅳ, Tiaozang Shumi Decoction has a more satisfactory therapeutic effect on chronic constipation of deficiency syndrome, and it can better improve the clinical symptoms and adverse psychological emotions of patients with lasting effect and good safety.

关键词

慢性便秘虚证调脏舒秘方焦虑抑郁

Keywords

chronic constipationdeficiency syndromeTiaozang Shumi Decoctionanxietydepression

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