Objective,2,This paper analyzed and summarized the rules of syndrome-treatment-prescription-medicine for traditional Chinese medicine (TCM) treatment of cervical spondylotic myelopathy (CSM) to provide reference for clinical practice.,Methods,2,Literatures about the treatment of cervical spondylotic myelopathy with oral administration of traditional Chinese medicine were collected and sorted out by searching China National Knowledge Infrastructure (CNKI) database, Wanfang Medical Network database and Chinese Sci & Tech Journals (VIP) database from January 1, 1990 to December 31, 2019. Excel 2010 software was used to calculate the frequency of syndromes, syndrome elements, prescriptions and traditional Chinese herbal medicines (TCHMs), SPSS21.0 software was used to cluster the high-frequency herbal medicines in the database, and SPSS Modeler 18.0 software was used to analyze the association rules of high-frequency TCHMs.,Results,2,①Fifty-nine qualified literatures were finally screened out, and 34 TCM syndromes of CSM were obtained after classification, of which liver and kidney deficiency syndrome, qi stagnation and blood stasis syndrome, channel-collateral stasis and obstruction syndrome and qi and blood deficiency syndrome were common syndromes, accounting for 58.82%. ②There were 6 elements manifesting excess disease nature, mainly blood stasis, qi stagnation and dampness obstruction and 4 elements manifesting deficiency disease nature, mainly qi deficiency, blood deficiency and governor channel deficiency. Zang-fu organs involved were mainly kidney and liver. ③There were 84 TCM prescriptions for the treatment of CSM, of which 46 were set prescriptions. The mostly used ones were Buyang Huanwu Decoction, Dihuang Yinzi Decoction, and Shengyu Decoction, etc. According to the classification based on the effects of commonly used prescriptions, it is found that tonifying prescriptions and blood-regulating prescriptions were the most frequently used, accounting for 78.26%. ④There were 165 kinds of TCHMs for the treatment of CSM. The high-frequency TCHMs in turn were Danggui (,Radix Angelicae Sinensis,), Huangqi (,Radix Astragali seu Hedysari,), Chuanxiong (,Rhizoma Ligustici Chuanxiong,), and Honghua (,Flos Carthami,), etc. Deficiency-tonifying TCHMs and blood circulation-promoting and blood stasis-removing TCHMs were commonly used for the treatment of CSM, of which deficiency-tonifying TCHMs were the most in kinds, accounting for 34.60%. ⑤Cluster analysis showed that TCHMs of high-frequency used in CSM treatment can be divided into three categories: For liver and kidney deficiency syndrome, the optional TCHMs were Niuxi (,Radix Achyranthis Bidentatae,), Dangshen (,Radix Codonopsis,), and Shanzhuyu (,Fructus Corni,), etc.; For qi deficency and blood stasis syndrome, the optional TCHMs were Danggui (,Radix Angelicae Sinensis,), Huangqi (,Radix Astragali seu Hedysari,), and Chuanxiong (,Rhizoma Ligustici Chuanxiong,); For channel-collateral stasis and obstruction syndrome, the optional TCHMs were Baishao (,Radix Paeoniae Alba,), Dilong (,Lumbricus,), and Chishao (,Radix Paeoniae Rubra,), etc. ⑥According to the association rules, 7 core TCHMs and 14 core TCHM combinations were obtained, of which a triangular TCHM group including Huangqi (,Radix Astragali seu Hedysari,), Danggui (,Radix Angelicae Sinensis,) and Chuanxiong (,Rhizoma Ligustici Chuanxiong,) was obtained. It was also found that the core TCHM combinations were mainly deficiency-tonifying TCHMs including Huangqi (,Radix Astragali seu Hedysari,), Danggui (,Radix Angelicae Sinensis,) and Baishao (,Radix Paeoniae Alba,), blood circulation-promoting and blood stasis-removing TCHMs including Chuanxiong (,Rhizoma Ligustici Chuanxiong,), Taoren (,Semen Persicae,) and Honghua (,Flos Carthami,), and liver-calming and wind-stopping TCHM including Dilong(,Lumbricus,).,Conclusion,2,It is feasible to analyze the rules of TCM treatment of cervical spondylotic myelopathy based on data mining, and the data mining results can provide valuable reference for clinical practice.