Advances in traditional Chinese medicine research of non-alcoholic fatty liver disease

Lina ZHOU; Junxiong LI; Dongying XUE

doi:10.16305/j.1007-1334.2021.2004219

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Advances in traditional Chinese medicine research of non-alcoholic fatty liver disease

更新时间：2022-08-03

- Advances in traditional Chinese medicine research of non-alcoholic fatty liver disease
- Shanghai Journal of Traditional Chinese Medicine Vol. 55, Issue 3, Pages: 93-97(2021)
- 作者机构：
  
  1.上海中医药大学附属普陀医院感染科（上海　200333）
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2021.2004219
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Lina ZHOU, Junxiong LI, Dongying XUE. Advances in traditional Chinese medicine research of non-alcoholic fatty liver disease. [J]. Shanghai Journal of Traditional Chinese Medicine 55(3):93-97(2021)
DOI：

Lina ZHOU, Junxiong LI, Dongying XUE. Advances in traditional Chinese medicine research of non-alcoholic fatty liver disease. [J]. Shanghai Journal of Traditional Chinese Medicine 55(3):93-97(2021) DOI： 10.16305/j.1007-1334.2021.2004219.

摘要

从病名、病因病机、临床治疗、实验研究等方面综述非酒精性脂肪性肝病（NAFLD）的中医研究进展。本病归属于中医学“肝癖”的范畴，其发病与情志、饮食、劳逸、久病迁延等因素相关，病机虚实相兼、寒热错杂，由肝郁、脾虚、湿聚、气滞、血瘀、痰凝等多种病理因素相互作用所致，攻补兼施是其基本治则。目前存在疾病不同阶段病机研究不够深入、缺乏统一的辨证标准及行之有效的科学评估体系等问题，建议依托代谢组学、基因组学等新兴系统生物学技术平台，拓宽中医药治疗NAFLD的物质基础及作用机制研究，助力NAFLD中医诊治的标准化、系统化及规范化。

Abstract

Advances in traditional Chinese medicine research of non-alcoholic fatty liver disease (NAFLD) were reviewed from the aspects of disease name, etiology and pathogenesis, clinical treatment, and experimental research. NAFLD belongs to the category of "Gan Pi" (liver stuffiness) in traditional Chinese medicine. Factors such as emotions, diet, work and rest, and prolonged illness, etc. are triggers for the onset of disease. Deficiency and excess complex, cold and heat complex are common pathogenesis due to the intermingling and interactions of various pathological factors such as liver depression, spleen deficiency, dampness accumulation, qi stagnation, blood stasis, and phlegm coagulation, etc. Clinically, the basic therapeutic principle is to combine tonification and purgation. At present, there are some problems such as insufficient in-depth research on pathogenesis of different stages of NAFLD, lack of unified syndrome differentiation standards and effective scientific evaluation system. The emerging systems biology technology platforms such as metabonomics and genomics are highly recommended for broadening the research on the material basis and action mechanism of traditional Chinese medicine in the treatment of NAFLD, and facilitating the standardization, systematization and normalization of traditional Chinese medicine diagnosis and treatment of NAFLD.

关键词

非酒精性脂肪性肝病代谢相关脂肪性肝病中医肝癖综述

Keywords

non-alcoholic fatty liver diseasemetabolic-related fatty liver diseasetraditional Chinese medicineGan Pireview

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