ZHANG Peiqiu’s experience in treatment of stevens-Johnson syndrome induced by carbamazepine from liver aspect: a case report

Zengxiang ZHANG; Xiping WU; Hongdan LIU; Liyun GE

doi:10.16305/j.1007-1334.2021.2003301

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ZHANG Peiqiu’s experience in treatment of stevens-Johnson syndrome induced by carbamazepine from liver aspect: a case report

更新时间：2022-08-03

- ZHANG Peiqiu’s experience in treatment of stevens-Johnson syndrome induced by carbamazepine from liver aspect: a case report
- Shanghai Journal of Traditional Chinese Medicine Vol. 55, Issue 7, Pages: 36-37(2021)
- 作者机构：
  
  1.宁波市医疗中心李惠利医院（浙江　宁波　315040）
  2.温州医科大学公共卫生管理学院（浙江　温州　325035）
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2021.2003301
  CLC：
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Zengxiang ZHANG, Xiping WU, Hongdan LIU, et al. ZHANG Peiqiu’s experience in treatment of stevens-Johnson syndrome induced by carbamazepine from liver aspect: a case report. [J]. Shanghai Journal of Traditional Chinese Medicine 55(7):36-37(2021)
DOI：

Zengxiang ZHANG, Xiping WU, Hongdan LIU, et al. ZHANG Peiqiu’s experience in treatment of stevens-Johnson syndrome induced by carbamazepine from liver aspect: a case report. [J]. Shanghai Journal of Traditional Chinese Medicine 55(7):36-37(2021) DOI： 10.16305/j.1007-1334.2021.2003301.

摘要

结合验案总结张沛虬从肝论治由卡马西平引起的史-约综合征的临床经验。根据用药史和临床特征，认为史-约综合征系由阳毒发于肌肤，引动肝热所致，治以养肝柔肝、清肝凉肝，方用四物汤加味。

Abstract

This paper introduces Zhang Peiqiu’s clinical experience in treating a case of Stevens-Johnson Syndrome induced by carbamazepine from liver aspect. According to the history of medication and clinical characteristics, it is considered that Stevens-Johnson Syndrome is caused by liver heat due to yang toxin in the skin, which is treated by nourishing the liver and emolliating the liver, clearing the liver and cooling the liver, and modified Siwu Decoction is used.

关键词

史-约综合征卡马西平从肝论治张沛虬

Keywords

Stevens-Johnson Syndromecarbamazepinetreatment from liver aspectZhang Peiqiu

references

MODI A, DESAI M, SHAH S, et al. Analysis of cutaneous adverse drug reactions reported at the regional ADR monitoring center [J]. Indian J Dermatol, 2019, 64(3): 250.

YANG C Y, DAO R L, LEE T J, et al. Severe cutaneous adverse reactions to antiepileptic drugs in Asians[J]. Neurology, 2011, 77(23): 2025-2033.

CUMBO N, WEINBERGER J, ALKHALIL M, et al. Anticonvulsant hypersensitivity syndrome: is there a role for immunomodulation?[J]. Epilepsia, 2008, 49(12): 2108-2112.

应军，肖百全，杨威，等. 鸡血藤与阿胶升白细胞作用的比较研究[J]. 中药新药与临床药理，2011, 22(2): 175-177.

王克勤. 张沛虬下法临床经验[J]. 江西中医药，1999, 30(2): 7.

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