Objective,2,To observe the clinical effect of muscle energy technique (MET) combined with directional penetration therapy of traditional Chinese medicine (TCM) on treatment of external humeral epicondylitis (EHE).,Method,2,A total of 100 patients with external humeral epicondylitis were randomly divided into the treatment group (,n,=50) and the control group (,n,=50). The treatment group was administered with TCM directional penetration therapy combined with MET, while the control group was administered with TCM directional penetration therapy alone. The course of treatment was 14 days in both groups. We observed and compared the change of pain visual analogue scale (VAS) scores, disability of arm-shoulder-hand (DASH) scores, and the maximum thickness of common extensor tendon of elbow joint on the affected side under ultrasound.,Results,2,There was no drop-out case during the trial. There were significant differences in VAS scores, DASH total scores and the maximum thickness of common extensor tendon of affected elbow joint before and after treatment in both groups (,P,<,0.05); after treatment, the improvement of VAS scores, DASH total scores and the maximum thickness of common extensor tendon of the affected side of the elbow joint in the treatment group was significantly better than that in the control group (,P,<,0.05).,Conclusion,2,MET combined with TCM directional penetration therapy is a feasible method of integrated traditional Chinese and western medicine therapy, which can relieve the pain of patients with EHE and improve the upper limb function of patients more effectively.