Objective:To observe the curative effect of Modified Danggui Powder combined with Shoutai Pill on the abnormal anti-phospholipid antibodies in patients of recurrent abortion. MethodsEighty patients of recurrent abortion with abnormal anti-phospholipid antibodies were enrolled and randomly divided into the treatment group(40 cases)and the control group(40 cases). The patients in the treatment group were treated with Modified Danggui Powder combined with Shoutai Pill with a course of three months,each month was one treatment course,and three treatment courses were continued after pregnancy. The patients in the control group were treated with aspirin,each month was one treatment course,the treatment course was not more than three months before pregnancy,and three months treatment was continued after pregnancy. The clinical effects of the two groups were evaluated; After one treatment course,two treatment courses,and three treatment courses,the anti-cardiolipin antibodies(ACA)and anti-β2 glycoprotein 1 antibodies(anti-β2-GP-1 Ab)were detected,and the negative conversion rates of the antibodies were compared between the two groups; after pregnancy of one month,two months,and three months,the levels of plasma fibrinogen(FIB)and D-dimer(DD)were tested; all the pregnant women were followed up until the end of pregnancy,and the pregnancy success rate was compared between the two groups; the incidence of adverse reactions was compared between the two groups.  Results:After three courses of treatment,the clinical total effective rates of the treatment group and the control group were 85.0% and 65.0% respectively,and the effect of the treatment group was better than that of the control group(P<0.05). After two courses and three courses of treatment, the negative conversion rates of ACA and anti-β2-GP-1 Ab in the treatment group were significantly higher than those in the control group(P<0.05,P<0.01). In the first three months of pregnancy,the levels of D-D and FIB in the treatment group were significantly lower than those in the control group(P<0.05,P<0.01). After treatment,the pregnancy success rates of the treatment group and the control group were 82.5% and 62.5% respectively,and the pregnancy success rate of the treatment group was obviously higher than that of the control group(P<0.05). In the course of treatment,the incidences of adverse reactions in the treatment group and the control group were 5.0% and 27.5% respectively,and the incidence of adverse reactions in the treatment group was obviously lower than that in the control group(P<0.05).  Conclusion:Modified Danggui Powder combined with Shoutai Pill can effectively promote the ACA and anti-β2-GP-1 Ab to change to negative,improve the hypercoagulability in pregnancy period,and enhance the pregnancy success rate in patients of recurrent abortion with abnormal anti-phospholipid antibodies.