Objective:To observe the clinical effect of the Miaoling Xianzi decoction for the syndrome of accumulated dampness-heat of acute gouty arthritis. MethodsNinety patients with the syndrome of accumulated dampness-heat of acute gouty arthritis were randomly divided into three groups.The tradition-medicine group was treated with Miaoling Xianzi decocti]on.The modern-medicine group was treated with colchicine.The tradition-modern medicine group was treated with Miaoling Xianzi decoction and colchicine.There were 30 cases in each group,which was followed up for 1 month,and recorded joint pain score,joint swelling score,joint function score,TCM symptom score,uric acid(UA) level,inflammatory cytokines,kidney function and adverse reactions before and after treatment in each group.Calculate the time required for the reduction of colchicine in the modern-medicine group and the tradition-modern medicine group.  Results:①After treatment,the joint pain score,joint swelling score,and joint function score of the tradition-modern medicine group were lower than tradition-medicine group and modern-medicine group(P<0.05).There was no significant difference between the tradition-medicine group and modern-medicine group(P>0.05).②After treatment,the improvement of TCM symptoms of the tradition-medicine group and the tradition-modern medicine group is better than that of modern-medicine group(P<0.05).③The efficacy of uric acid(UA)of the tradition-medicine group and the tradition-modern medicine group was significantly better than the modern-medicine group(P<0.01).There was no statistical difference in the White blood cells(WBC), Erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),Serum creatinine(SCR)and Blood urea nitrogen(BUN) in three groups(P>0.05).④The adverse reaction rate of the tradition-medicine group and the tradition-modern medicine group were significantly lower than the modern-medicine group(P<0.05).⑤The time required for colchicine reduction in the tradition-modern medicine group was less than the modern-medicine group(P<0.05).  Conclusion:Miaoling Xianzi decoction is not inferior to anti-inflammation and to relieve pain than colchicine in the treatment for accumulated dampness-heat of acute gouty arthritis,with the effect of lower uric acid and lower probability of adverse reactions.