WU Tingting. Data mining of tongue images, pulse diagnosis and medication rules of seasonal pathogen induced diseases in children. [J]. Shanghai Journal of Traditional Chinese Medicine 54(6):66-71(2020)
DOI:
WU Tingting. Data mining of tongue images, pulse diagnosis and medication rules of seasonal pathogen induced diseases in children. [J]. Shanghai Journal of Traditional Chinese Medicine 54(6):66-71(2020) DOI: 10.16305/j.1007-1334.2020.06.004.
Data mining of tongue images, pulse diagnosis and medication rules of seasonal pathogen induced diseases in children
Objective:To study the characteristics of tongue images, pulse conditions and medication rules of seasonal pathogen induced diseases in children based on the data mining method. MethodsA standardized database was established by including medical records of 634 cases of seasonal pathogen induced diseases in children extracted from the Collection of Pediatric Medical Records of Past Dynasties, and the correlation between tongue images, pulse diagnosis and Chinese herbal medicines (CHMs) and the medication rules were analyzed by using frequency statistics, logistic regression analysis, association rules and other methods. Results:①A total of 634 cases of medical records from Han dynasty to modern times were included, involving 634 prescriptions and 250 kinds of CHMs. ②There were 23 kinds of seasonal pathogen induced diseases in children, most of which were exogenous warm febrile diseases. There were 16 kinds of tongue images with frequency greater than or equal to 4. The tongue images mainly indicated a heat syndrome, including red tongue, crimson tongue and prickly tongue, etc., with greasy coating, yellow coating, white coating or thick coating, etc. There were 16 kinds of pulse conditions with frequency greater than or equal to 3, most of which were rapid pulse, slippery pulse, wiry pulse and fine pulse, etc. There were 22 kinds of CHMs with frequency greater than or equal to 82, which were Xingren (Armeniacae Semen Amarum), Gancao (Radix Glycyrrhizae), Lianqiao (Fructus Forsythiae), etc. ③There were 15 strong correlations between tongue images and CHMs. For instance, red tongue had a strong correlation with Digupi (Cortex Lycii), Zhuli (Succus Bambusae) and Gualou (Fructus Trichosanthis); greasy coating had a strong correlation with Paojiang (Rhizoma Zingiberis Preparata), Peilan (Herba Eupatorii) and Mahuang (Herba Ephedrae); and yellow coating had a strong correlation with Dangshen (Radix Codonopsis), Huanglian (Rhizoma Coptidis) and Zhishi (Fructus Aurantii Immaturus). ④There were 13 strong correlations between pulse conditions and CHMs. For instance, rapid pulse had a strong correlation with Douchi (Semen Sojae Preparatum), Gegen (Radix Puerariae) and Xuanshen (Radix Scrophulariae); slippery pulse had a strong correlation with Zhuli (Succus Bambusae), Rendongteng (Caulis Lonicerae) and Digupi (Cortex Lycii); and wiry pulse had a strong correlation with Xiakucao (Prunella Vulgaris), Juluo (Citri Reticulatae Exocarpium Album) and Rendongteng (Caulis Lonicerae), etc. ⑤The drug pairs with high confidence were Pipaye (Folium Eriobotryae) and Zhebeimu (fritillaria thunbergii), Ziwan (Radix Asteris) and Xingren (Armeniacae Semen Amarum), Bohe (Herba Menthae) and Lianqiao (Fructus Forsythiae), etc. The drug pairs with high support were Zhebeimu (fritillaria thunbergii) and Xingren (Armeniacae Semen Amarum), Jinyinhua (Flos Lonicerae) and Lianqiao (Fructus Forsythiae), Shanzhizi (Fructus Gardeniae) and Lianqiao (Fructus Forsythiae), etc. ⑥The correlations between tongue images and pulse conditions with high confidence were yellow coating and rapid pulse, white coating and rapid pulse, red tongue and rapid pulse, etc. The correlations between tongue images and pulse conditions with high support were red tongue and rapid pulse, greasy coating and rapid pulse, yellow coating and rapid pulse, etc. Conclusion:Seasonal pathogen induced diseases recorded in the Collection of Pediatric Medical Records of Past Dynasties mostly have damp-heat tongue images, pulse conditions are rapid pulse, slippery pulse and wiry pulse, and most CHMs used are Xingren (Armeniacae Semen Amarum), Gancao (Radix Glycyrrhizae) and Lianqiao (Fructus Forsythiae), etc. There are correlations among certain tongue images, pulse conditions and CHMs used and association rules in the compatibility of CHMs. Modern pediatric clinical practice of traditional Chinese medicine may learn from the experience of diagnosis and treatment in pediatric medical records of previous dynasties.
关键词
时行疾病小儿舌象脉象中医诊断中药诊疗规律数据挖掘回归分析
Keywords
epidemic diseaseschildrentongue imagepulse conditiontraditional Chinese medicine diagnosisChinese herbal medicinerule of diagnosis and treatmentdata miningregression analysis
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