Relevant factors in sleep-awakening mechanism and research progress in its regulation with Chinese medicine 

LI Yixia; XU Jian; LI Ou; SHA Zhongwei; LI Zhimin

doi:10.16305/j.1007-1334.2019.12.022

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Relevant factors in sleep-awakening mechanism and research progress in its regulation with Chinese medicine 

更新时间：2022-08-31

- Relevant factors in sleep-awakening mechanism and research progress in its regulation with Chinese medicine 
- Shanghai Journal of Traditional Chinese Medicine Vol. 53, Issue 12, Pages: 89-92(2019)
- 作者机构：
  
  1. 上海中医药大学附属市中医医院睡眠研究所,上海,200070
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2019.12.022
  CLC：
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LI Yixia, XU Jian, LI Ou, et al. Relevant factors in sleep-awakening mechanism and research progress in its regulation with Chinese medicine . [J]. Shanghai Journal of Traditional Chinese Medicine 53(12):89-92(2019)
DOI：

LI Yixia, XU Jian, LI Ou, et al. Relevant factors in sleep-awakening mechanism and research progress in its regulation with Chinese medicine . [J]. Shanghai Journal of Traditional Chinese Medicine 53(12):89-92(2019) DOI： 10.16305/j.1007-1334.2019.12.022.

摘要

综述睡眠-觉醒机制的相关因素及中药对其调节的研究进展。随着神经解剖学、药理学、分子生物学等技术方法的发展,发现睡眠-觉醒机制与众多因素有关,如下丘脑-垂体-肾上腺轴、褪黑素、多巴胺、5-羟色胺、神经肽、乙酰胆碱、γ-氨基丁酸能等；加味四逆散、加味逍遥散等中药可通过调节激素水平及神经递质影响睡眠-觉醒机制。

Abstract

The relevant factors in sleep-awakening mechanism and research progress in its regulation with Chinese medicine are reviewed. With the development of neuroanatomy, pharmacology and molecular biology, it has been found that sleep-awakening mechanism is related to many factors, such as the thalamus-pituitary-adrenal axis, the melatonin system, dopamine, 5-hydroxytryptamine, neuropeptide, acetylcholine and gamma-aminobutyric acid etc. Recipes in TCM like Modified Sini Powder and Modified Xiaoyao Powder can influence the sleep-awakening mechanism by regulating hormone levels and neurotransmitters.

关键词

睡眠-觉醒节律中医药疗法分子神经生物学调节机制综述

Keywords

sleep-awakening rhythmtherapy in traditional Chinese medicinemolecular neurobiologyregulatory mechanismsreview

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