The mechanisms and progress of Chinese medicine against Candida

LI Zhen; CHEN Weiqin; HU Jun; YIN Hongmei; PENG Yibing; HU Xiaobo

doi:10.16305/j.1007-1334.2019.12.021

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The mechanisms and progress of Chinese medicine against Candida

更新时间：2022-08-31

- The mechanisms and progress of Chinese medicine against Candida
- Shanghai Journal of Traditional Chinese Medicine Vol. 53, Issue 12, Pages: 83-88(2019)
- 作者机构：
  
  1. 上海中医药大学附属龙华医院检验科,上海,200032
  2. 上海交通大学附属瑞金医院检验科,上海,200025
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2019.12.021
  CLC：
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LI Zhen, CHEN Weiqin, HU Jun, et al. The mechanisms and progress of Chinese medicine against Candida. [J]. Shanghai Journal of Traditional Chinese Medicine 53(12):83-88(2019)
DOI：

LI Zhen, CHEN Weiqin, HU Jun, et al. The mechanisms and progress of Chinese medicine against Candida. [J]. Shanghai Journal of Traditional Chinese Medicine 53(12):83-88(2019) DOI： 10.16305/j.1007-1334.2019.12.021.

摘要

综述中药抗念珠菌现状及抑菌机制研究进展。研究表明中药中某些单体成分、提取物及复方均能抑制致病念珠菌生长,可以抑制其毒力因子(水解酶、菌丝、生物膜)活性及相关基因的表达,或促进内源性活性氧的生成,从而加重菌体细胞氧化损伤。

Abstract

This paper reviews the mechanisms and progress of Chinese medicine against Candida. Studies have shown that some monomer components,extracts,and prescriptions of traditional Chinese medicine can inhibit the growth of pathogenic Candida. Besides restraining the expression of virulence factors(hydrolase,mycelium,biofilm)and related genes,they can promote the production of endogenous reactive oxygen species and aggravate the oxidative damage of yeast cells.

关键词

念珠菌中草药单体机制研究综述

Keywords

Candidatraditional Chinese medicinemonomermechanism researchreview

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