Syndrome element differentiation of diabetic foot gangrene(tendon gangrene) based on factor analysis and cluster analysis

LI Liangliang; XIANG Shengmin; LUO Yun; WANG Weiling; ZHAO Cheng

doi:10.16305/j.1007-1334.2019.10.006

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Syndrome element differentiation of diabetic foot gangrene(tendon gangrene) based on factor analysis and cluster analysis

更新时间：2022-08-31

- Syndrome element differentiation of diabetic foot gangrene(tendon gangrene) based on factor analysis and cluster analysis
- Shanghai Journal of Traditional Chinese Medicine Vol. 53, Issue 10, Pages: 24-27(2019)
- 作者机构：
  
  1. 上海中医药大学附属上海市中西医结合医院脉管病科,上海,200082
  2. 上海市中西医结合脉管病研究所,上海,200082
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2019.10.006
  CLC：
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LI Liangliang, XIANG Shengmin, LUO Yun, et al. Syndrome element differentiation of diabetic foot gangrene(tendon gangrene) based on factor analysis and cluster analysis. [J]. Shanghai Journal of Traditional Chinese Medicine 53(10):24-27(2019)
DOI：

LI Liangliang, XIANG Shengmin, LUO Yun, et al. Syndrome element differentiation of diabetic foot gangrene(tendon gangrene) based on factor analysis and cluster analysis. [J]. Shanghai Journal of Traditional Chinese Medicine 53(10):24-27(2019) DOI： 10.16305/j.1007-1334.2019.10.006.

摘要

目的：探索糖尿病足坏疽(筋疽型)的中医证候分布规律,为糖尿病足坏疽(筋疽型)的中医辨证及其客观化、规范化研究提供参考依据。方法：纳入136例糖尿病足坏疽(筋疽型)患者,制定糖尿病足坏疽(筋疽型)四诊信息采集表,建立数据库,采用因子分析、聚类分析等统计学方法及证素辨证的方法,进行中医证候研究。结果：因子分析共获得17个公因子,结合专业知识进行聚类分析,依据证素辨证的方法获得4种有效中医证型,占比由高到低依次为湿热毒盛证、血脉瘀阻证、气血两虚证、热毒伤阴证。结论：糖尿病足坏疽(筋疽型)以湿热毒盛证最为多见,湿热为其主要证素；其余依次为血脉瘀阻证、气血两虚证、热毒伤阴证。

Abstract

Objective:To explore the distribution pattern of TCM syndromes of diabetic foot gangrene (tendon gangrene), and to provide reference for TCM syndrome differentiation and its objectification and standardization of diabetic foot gangrene (tendon gangrene). Methods136 patients with diabetic foot gangrene (tendon gangrene) were included, a four-diagnostic-method information collection table for diabetic foot gangrene (tendon gangrene) and a database were established. Statistical methods such as factor analysis and cluster analysis, and syndrome element differentiation methodology were used to conduct TCM syndrome research. Results:A total of 17 common factors were obtained by factor analysis, a cluster analysis was performed considering professional knowledge, and 4 valid TCM syndromes were obtained according to the method of syndrome element differentiation. The syndromes are the following in the descending order: syndrome of excessive dampness-heat and toxin, syndrome of blood vessel stasis and obstruction, syndrome of qi and blood deficiency and syndrome of toxic heat injuring yin. Conclusion:The most commonly-seen syndrome of diabetic foot gangrene (tendon gangrene) is syndrome of excessive dampness-heat and toxin, with dampness-heat being the main syndrome element; followed by syndrome of blood vessel stasis and obstruction, syndrome of qi and blood deficiency and syndrome of toxic heat injuring yin.

关键词

糖尿病足坏疽筋疽型中医证候证素辨证湿热毒盛证

Keywords

diabetic foot gangrenetendon gangreneTCM syndromesyndrome element differentiationsyndrome of excessive dampness-heat and toxin

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