This paper introduces Professor Xu Lianwei’s clinical experience of treating climacteric syndrome with herbal paste. Professor Xu thinks that the pathogenesis of climacteric syndrome is the defieiency of the liver and kidney, the dysfunction of zang-fu organs and the imbalance of qi and blood. The treatment principle is to adjust the liver and kidney, to balance yin and yang, and to strengthen the spleen and harmonize the stomach as considering the restriction among the five viscera. Herbal paste for climacteric syndrome can specially nourish zang-fu organs as well as nourish yin and yang, qi and blood. One proven case is presented.