Objective:To systematically evaluate the effectiveness and safety of rotary drawing manipulation in the treatment of frozen shoulder. MethodsLiteratures about clinical randomized controlled trials (RCTs) on rotary drawing manipulation for frozen shoulder were electronically searched from Pubmed, Cochrane library, Embase, CBM, CNKI, VIP, WANGFANG and other databases at home and abroad from 2007 to 2017, and final literatures were manually selected based on inclusion and exclusion criteria to extract valid data. Quality evaluation was performed on the included studies by the Cochrane systematic evaluation method, and meta-analysis was conducted on data using the RevMan 5.3 software.  Results:①Ten RCT literatures involving 1084 patients with frozen shoulder were included. ②Most of the 10 studies included did not describe or were not clear about the criteria of assignment masking, blinding, being lost to follow-up or withdrawal, and the overall quality of literatures was low. ③Meta-analysis showed that the treatment group (rotary drawing manipulation therapy) was superior to the control group (other non-drug therapy) in increasing the total effective rate [RR=1.19,5% CI (1.10,1.29), P＜0.000 1], the curative rate [RR=1.42,5% CI (1.05,1.92), P=0.02] and improving the VAS score [manipulation vs acupuncture and moxibustion:WMD=-0.73,5% CI (-1.08, -0.39), P＜0.000 1; manipulation vs block:WMD=-1.50,5% CI (-1.88, -1.12); Z=7.79, P＜0.000 01].  Conclusion:Rotary drawing manipulation therapy improves the symptoms of frozen shoulder, with efficacy superior to the other non-drug therapies. However, more multi-center randomized controlled trials with a larger sample size are needed to further confirm the conclusion due to the poor quality of methodology for including the literatures and the differences among the studies included.