Objective:To study the endometrial thickness, volume, endometrial blood flow pattern and uterine blood flow parameters at midluteal phase in patients with persistent thin endometrium and the effect of Ma’s Bubao Decoction combined with acupuncture on endometrial receptivity (ER) in them. MethodsNinety cases of persistent thin endometrium of childbearing age were randomly divided into treatment group and control group, 45 cases in each group . In addition, 30 women of normal childbearing age in the same period were included as normal control group .The control group was treated with aspirin, while the treatment group was treated with Ma’s Bubao Decoction and acupuncture on the basis of aspirin. Both groups were treated for 2 months (suspend treatment during menstrual period) and then the changes of endometrial thickness, volume, endometrial blood flow pattern, uterine blood flow hemodynamic parameters and TCM syndrome scores at midluteal phase were observed.  Results:①During the experiment, there were 3 cases dropped in the treatment group (due to interruption of treatment), 2 cases in the control group, and no drop in the normal control group. Totally 115 cases completed the experiment, 42 cases in the treatment group, 43 cases in the control group and 30 cases in the normal control group. ②At midluteal phase, the thickness and volume of endometrium in the thin endometrium group were significantly lower than those in the normal control group (P < 0.05); the levels of endometrial blood flow S/D and uterine artery blood flow mPI, mRI and mS/D were significantly higher than those in the normal control group (P < 0.05); the difference of endometrial blood flow pattern between the two groups was significant (P < 0.05). ③In the midluteal phase, there were significant differences in endometrial thickness, endometrial volume, endometrial blood flow S/D, uterine artery blood flow mPI and endometrial blood flow pattern compared with those before treatment within both groups (P < 0.05), and there were significant differences in the uterine artery blood flow mS/D in the treatment group (P<0.05). There were significant differences in endometrial thickness, endometrial blood flow S/D and uterine artery mS/D between the two groups after treatment. The improvement of the above indexes in the treatment group was significantly better than that in the control group (P<0.05). There was no significant difference in endometrial blood flow pattern (P>0.05). ④ There were significant differences in TCM syndrome scores compared with those before treatment within both groups (P<0.05). All of them were significantly decreased after treatment. After treatment, the TCM syndrome scores in the treatment group were significantly lower than those in the control group (P<0.05).  Conclusion:①The resistance of uterine blood flow at midluteal phase of persistent thin endometrium patients was significantly higher than that of normal women, and the endometrial thickness and volume were significantly decreased. ②On the basis of oral aspirin, the combination of Ma’s Bubao Decoction and acupuncture can improve the clinical symptoms of patients with persistent thin endometrium, increase the thickness and volume of endometrium and enhance the blood flow perfusion of the uterus,which are conducive to the improvement of endometrial receptivity.