Effects of Erbai Decoction combined with amlodipine besylate on morning blood pressure surge in patients with hypertension

WANG Lei; CHENG Yanmei; FAN Jiawei; YUE Yaohan; WANG Zhijun; YU Qingqing; WANG Yingyu; WANG Qiaochu

doi:10.16305/j.1007-1334.2019.02.016

您当前的位置：

首页 >

文章列表页 >

Effects of Erbai Decoction combined with amlodipine besylate on morning blood pressure surge in patients with hypertension

更新时间：2022-08-31

- Effects of Erbai Decoction combined with amlodipine besylate on morning blood pressure surge in patients with hypertension
- Shanghai Journal of Traditional Chinese Medicine Vol. 53, Issue 2, Pages: 61-63(2019)
- 作者机构：
  
  1. 上海市普陀区人民医院中医科,上海,200060
  2. 上海中医药大学附属岳阳中西医结合医院消化科,上海,200032
  3. 上海中医药大学附属市中医医院睡眠疾病研究所,上海,200071
- 作者简介：
- 基金信息：
- DOI：10.16305/j.1007-1334.2019.02.016
  CLC：
扫描看全文
WANG Lei, CHENG Yanmei, FAN Jiawei, et al. Effects of Erbai Decoction combined with amlodipine besylate on morning blood pressure surge in patients with hypertension. [J]. Shanghai Journal of Traditional Chinese Medicine 53(2):61-63(2019)
DOI：

WANG Lei, CHENG Yanmei, FAN Jiawei, et al. Effects of Erbai Decoction combined with amlodipine besylate on morning blood pressure surge in patients with hypertension. [J]. Shanghai Journal of Traditional Chinese Medicine 53(2):61-63(2019) DOI： 10.16305/j.1007-1334.2019.02.016.

摘要

目的：观察二白汤联合苯磺酸氨氯地平对高血压患者晨峰血压的影响。方法：将72例高血压患者随机分为治疗组和对照组,每组36例；两组均予苯磺酸氨氯地平口服,治疗组同时加服二白汤。两组疗程均为28天,观察24 h平均收缩压(SBP)、24 h平均舒张压(DBP)、24 h血压达标率、晨峰血压控制率,以及改进SPIEGEL睡眠量表评分变化情况。结果：①=1\*GB3两组治疗后24 h平均SBP和DBP均明显下降(P<0.05),但组间差异无统计学意义(P>0.05)。②=2\*GB3治疗前后组内比较,两组血压晨峰值及SPIEGEL睡眠量表评分差异均有统计学意义(P<0.05)；组间治疗后比较,血压晨峰值及SPIEGEL睡眠量表评分差异有统计意义(P<0.05)。③=3\*GB3治疗组24 h平均血压达标率为88.9%、晨峰血压控制率为91.7%,对照组分别为67.7%、44.4%,治疗组明显优于对照组(P<0.05)。结论：本观察结果提示,二白汤联合苯磺酸氨氯地平治疗高血压患者晨峰血压疗效明确,不仅24 h动态血压和晨峰血压控制良好,而且可以明显改善睡眠质量。

Abstract

Objective:To observe the effects of Erbai Decoction combined with amlodipine besylate on morning blood pressure surge in patients with hypertension. Methods72 patients with hypertension were randomly assigned into the treatment group and the control group, 36 patients in each group. Oral amlodipine besylate was given to patients in both groups and patients in the treatment group received Erbai Decoction in addition. The duration of treatment was 28 days in both groups. The 24h mean systolic blood pressure (SBP), 24h mean diastolic blood pressure (DBP), 24h control rate of blood pressure, control rate of morning blood pressure surge and changes in scores on the modified SPIEGEL sleep scale were observed. Results:①After treatment, 24h mean SBP and DBP decreased significantly in the groups (P<0.05), but with no statistically significant difference between the groups (P>0.05). ②There were statistically significant differences in values of morning blood pressure surge and scores on the SPIEGEL sleep scale in the groups before and after treatment (P<0.05); and there were statistically significant differences in values of morning blood pressure surge and scores on the SPIEGEL sleep scale (P<0.05) between the groups after treatment (P<0.05). ③The 24h control rate of blood pressure and control rate of morning blood pressure surge were 88.9% and 91.7% respectively in the treatment group, and were 67.7% and 44.4% respectively in the control group, with the treatment group significantly superior to the control group (P<0.05). Conclusion:The observation results indicate that Erbai Decoction combined with amlodipine besylate has definite efficacy in the treatment of hypertension, as the 24h ambulatory blood pressure and morning blood pressure surge are well controlled, and the quality of sleep is improved remarkably.

关键词

高血压晨峰血压二白汤动态血压睡眠障碍

Keywords

hypertensionmorning blood pressure surgeErbai Decoctionambulatory blood pressuresleep disorders

references

Views

121

下载量

CSCD

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Parametric feature analysis on ambulatory blood pressure in elderly patients with hypertension of yin deficiency and yang excess syndrome

Exploring approach and methods of balancing yin⁃yang in treating insomnia

Explore relationship between gut microbiota and hypertension based on the theory of “the heart and small intestine forming an exterior and interior relationship”

Analysis of factors influencing sleep disorders and the distribution characteristics of traditional Chinese medicine syndromes in people with early⁃or mid⁃stage Parkinson’s disease

Research progress on prevention and treatment of hypertensive left ventricular hypertrophy by traditional Chinese medicine

Related Author

No data

Related Institution

Department of Cardiology,Guang’anmen Hospital,China Academy of Traditional Chinese Medicine

Beijing University of Chinese Medicine

Preventive Treatment Center，Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine

Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine

Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

⁰