Objective:To observe the clinical efficacy of Qinjiang Baoling Decoction in the treatment of non-alcoholic fatty liver disease (NAFLD) of phlegm-blood stasis type. Methods100 patients with NAFLD of phlegm-blood stasis type were randomly assigned into the treatment group and the control group, 50 patients in each group. Diet control, exercise therapy and symptomatic treatment including lowering blood fat and sugar were prescribed to patients in the control group and patients in the treatment group received Qinjiang Baoling Decoction in addition. Patients in the two groups were treated for 3 months and then followed up for 3 months. The clinical efficacy was observed, and the changes in TCM syndrome score, liver function [alanine transferase (ALT) and γ-glutamamide transferase (γ-GT)], blood fat [total cholesterol (TC) and high density lipoprotein (HDL-C)], body mass index (BMI), insulin resistance index (HOMA-IR), score of abdomen B-mode ultrasound and liver/spleen CT ratio were compared between the groups.  Results:① At 3 months after treatment, the total effective rate was 64.0% and 52.0% in the treatment group and the control group respectively, and the clinical efficacy in the treatment group was superior to that in the control group (P<0.05). ② The scores of hypochondriac pain, fullness and rigidity, fullness of the chest and epigastrium, swollen eyes and bitter taste in the mouth, and waist soreness and limb heaviness decreased significantly in the groups after treatment compared to those before treatment (P<0.05); and at 3 months after treatment, there were statistically significant differences in the scores of hypochondriac pain, fullness of the chest and epigastrium and waist soreness and limb heaviness between the groups (P<0.05). ③ The levels of ALT, γ-GT and TC in serum decreased significantly in the groups after treatment compared to those before treatment (P<0.05); and at 3 months after treatment, the levels of ALT, γ-GT and TC in serum were lower in the treatment group than in the control group (P<0.05). ④ In the treatment group, the values of BMI and HOMA-IR decreased after treatment compared to those before treatment (P<0.05); and there were no statistically significant differences in the control group (P>0.05). ⑤ In the treatment group, there were statistically significant differences in the scores of abdomen B-mode ultrasound and liver/spleen CT ratio before and after treatment (P<0.05); and there was only statistically significant difference in the score of abdomen B-mode ultrasound in the control group (P<0.05). At 3 months after treatment, there were statistically significant differences in the score of abdomen B-mode ultrasound and liver/spleen CT ratio between the groups (P<0.05).  Conclusion:Qinjiang Baoling Decoction shows satisfactory efficacy in the treatment of NAFLD of phlegm-blood stasis type. It improves the clinical symptoms, regulates liver function and the level of blood fat, inhibits insulin resistance and promotes recovery of liver morphology with sustained effects.