LIU Fang, YU Jianer, ZHANG Xinguang, et al. Clinical efficacy evaluation on therapy of integrated traditional Chinese and western medicine by stages in controlling bronchial asthma in children. [J]. Shanghai Journal of Traditional Chinese Medicine 52(12):39-43(2018)
DOI:
LIU Fang, YU Jianer, ZHANG Xinguang, et al. Clinical efficacy evaluation on therapy of integrated traditional Chinese and western medicine by stages in controlling bronchial asthma in children. [J]. Shanghai Journal of Traditional Chinese Medicine 52(12):39-43(2018) DOI: 10.16305/j.1007-1334.2018.12.012.
Clinical efficacy evaluation on therapy of integrated traditional Chinese and western medicine by stages in controlling bronchial asthma in children
Objective:To observe the clinical efficacy of therapy of integrated traditional Chinese and western medicine by stages in treating bronchial asthma in children. Methods80 children with bronchial asthma were randomly divided into the treatment group and control group, 40 cases in each group. The control group was treated with western medicine according to GINA guidelines. The treatment group was treated with integrated traditional Chinese and western medicine by stages, with a treatment course of four and a half months and follow-up for one year. The clinical efficacy was observed, and the changes of main symptoms and signs scores and lung function indexes were compared, and the children asthma control test (C-ACT) questionnaire score was used to assess and compare the long-term control level of asthma. Results:①The total effective rates were 92.5% in the treatment group and 87.5% in the control group. The clinical efficacy of the treatment group was better than that of the control group, but with no statistically significant difference (P,>,0.05). ②Compared with treatment before, the main symptoms and signs scores were obviously decreased in both groups after treatment for one and a half months and at the end of treatment, with statistically significant differences (P,<,0.05). After treatment for one and a half months, the main symptoms and signs scores in the treatment group were significantly lower than those in the control group (P,<,0.05). At the end of the treatment, the main symptoms and signs scores in the treatment group were significantly lower than those in the control group (P,<,0.05). ③Compared with treatment before, the C-ACT score was significantly increased in both groups at the end of the treatment, after follow-up for 6 months and 1 year, respectively (P,<,0.05). Compared between the end of the treatment and follow-up for 1 year, the C-ACT score in the control group was significantly decreased (P,<,0.05), while no statistically significant difference on C-ACT score was observed in the treatment group (P,>,0.05). The C-ACT score in the treatment group was obviously higher than that in the control group after follow-up for 1 year (P,<,0.05). ④Compared with treatment before, the levels of FEV,1,% and PEF% were significantly increased in both groups at the end of the treatment, with statistically significant differences (P,<,0.05). At the end of the treatment, there were no statistically significant differences on the levels of FEV,1,% and PEF% between the two groups (P,>,0.05). Conclusion:At the whole stage of bronchial asthma in children, the therapy of integrated traditional Chinese and western medicine by stages shows equivalent clinical efficacy with western medicine therapy, while the therapy of integrated traditional Chinese and western medicine by stages shows advantages in improving symptoms and signs in the chronic persistent phase and clinical remission stage and enhancing long-term efficacy of asthma controlling during follow-up.
关键词
儿童哮喘中西医结合分期治疗病情控制C-ACT评分远期疗效
Keywords
childhood asthmaintegrated traditional Chinese and western medicinetreatment by stagesdisease controlC-ACT scorelong-term efficacy