This paper analyzes the main annotations of “treating yin in yang disease and treating yin in yang disease”in past dynasties. It is wrong to understand this as the treatment methods for yin deficiency and yang deficiency syndromes,because this yin and yang refer to different parts of the body. It is considered that the whole sentence means the disease of yang part of the body can be treated from yin part,and the disease of yin part can be treated from yang part,which contrasted with“treating yang in yang disease and treating yin in yin disease”. Its thinking characteristic is that the local pain is surveyed in the overall relationship,and the role of various parts of the body in the treatment of diseases is emphasized and fully played.