Review of lncRNA acting as competitive endogenous RNA in hepatocellular carcinoma regulation and mechanism research of Chinese medicine

SHI Miao-juan; GUO Xin-xin; SHANG Jia-wei; SU Shi-bing; ZHANG Hui

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Review of lncRNA acting as competitive endogenous RNA in hepatocellular carcinoma regulation and mechanism research of Chinese medicine

更新时间：2022-08-31

- Review of lncRNA acting as competitive endogenous RNA in hepatocellular carcinoma regulation and mechanism research of Chinese medicine
- Shanghai Journal of Traditional Chinese Medicine Vol. 51, Issue 11, Pages: 91-96(2017)
- 作者机构：
  
  1. 上海中医药大学交叉科学研究院中医复杂系统研究中心,上海,201203
- 作者简介：
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SHI Miao-juan, GUO Xin-xin, SHANG Jia-wei, et al. Review of lncRNA acting as competitive endogenous RNA in hepatocellular carcinoma regulation and mechanism research of Chinese medicine. [J]. Shanghai Journal of Traditional Chinese Medicine 51(11):91-96(2017)
DOI：

SHI Miao-juan, GUO Xin-xin, SHANG Jia-wei, et al. Review of lncRNA acting as competitive endogenous RNA in hepatocellular carcinoma regulation and mechanism research of Chinese medicine. [J]. Shanghai Journal of Traditional Chinese Medicine 51(11):91-96(2017) DOI：

摘要

针对lncRNA作为ceRNA与miRNA(lncRNA/miRNA/mRNA)相互作用调控肝癌的进展进行综述,包括lncRNA/miRNA/mRNA在肝癌发生发展进程中的功能、机制,lncRNA/miRNA/mRNA调控通路与中药作用机制研究。lncRNA/miRNA/mRNA丰富了肝癌的发生、发展机制,为肝癌诊断及治疗提供新思路。

Abstract

Long noncoding RNA (lncRNA),as competitive endogenous RNA (ceRNA),can interact with miRNA(lncRNA/miRNA/mRNA)and play the role in the regulation of hepatocellular carcinoma. This paper reviews the functions and mechanisms of lncRNA/miRNA/mRNA in the occurrence and development of hepatocellular carcinoma,and researches about lncRNA/miRNA/mRNA regulation pathway and Chinese medicine mechanism. lncRNA/miRNA/mRNA enrich the occurrence and development mechanism of hepatocellular carcinoma,and provide novel insight into the diagnosis and therapy of hepatocellular carcinoma.

关键词

lncRNAceRNAmiRNA肝癌中药机制综述

Keywords

lncRNAceRNAmiRNAhepatocellular carcinomaChinese medicine mechanismreview

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