Clinical observation of acupuncture combined with auricular therapy and three-step analgesic ladder in treating cancer pain

WU Ji; WANG Yao; ZHANG Yan; ZHAO Hai-yin; WANG Zhong-qi

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Clinical observation of acupuncture combined with auricular therapy and three-step analgesic ladder in treating cancer pain

更新时间：2022-08-31

- Clinical observation of acupuncture combined with auricular therapy and three-step analgesic ladder in treating cancer pain
- Shanghai Journal of Traditional Chinese Medicine Vol. 51, Issue 10, Pages: 48-51(2017)
- 作者机构：
  
  1. 上海中医药大学附属龙华医院肿瘤科,上海,200032
  2. 上海交通大学附属仁济医院妇科,上海,200135
- 作者简介：
- 基金信息：
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WU Ji, WANG Yao, ZHANG Yan, et al. Clinical observation of acupuncture combined with auricular therapy and three-step analgesic ladder in treating cancer pain. [J]. Shanghai Journal of Traditional Chinese Medicine 51(10):48-51(2017)
DOI：

WU Ji, WANG Yao, ZHANG Yan, et al. Clinical observation of acupuncture combined with auricular therapy and three-step analgesic ladder in treating cancer pain. [J]. Shanghai Journal of Traditional Chinese Medicine 51(10):48-51(2017) DOI：

摘要

目的：观察针灸联合耳穴疗法配合三阶梯止痛药治疗癌性疼痛的临床疗效。方法：将120例癌性疼痛患者随机分为治疗组与对照组,每组60例。两者均予基础三阶梯止痛药物,治疗组加用针灸联合耳穴疗法,对照组加用假针灸联合假耳穴疗法。两组疗程均为 21日,观察三阶梯止痛药的使用情况与副反应情况,比较疼痛强度视觉模拟评分(VAS)、生存质量评分(ZPS)及自然杀伤细胞(NK)、T细胞(CD3,+,、CD4,+,、CD8,+,、CD4,+,/CD8,+,)水平的变化情况。结果： ①最终完成试验者114例,治疗组58例,对照组56例。②组间治疗后比较,VAS评分差异有统计学意义,治疗组明显低于对照组(P,<,0.05)。③疗程结束时,治疗组有58.62%的患者有效减用或降阶梯使用止痛药,对照组有17.86%的患者有效减用或降阶梯使用止痛药；组间减药有效率比较,差异有统计学意义(P,<,0.05)。④疗程结束时,治疗组34.48%的患者止痛药副反应减少,对照组21.43%的患者止痛药副反应减少；组间减副反应有效率比较,差异有统计学意义,治疗组明显高于对照组(P,<,0.05)。⑤组间治疗后比较,ZPS评分差异有统计学意义,治疗组明显低于对照组(P,<,0.05)。⑥组间治疗后比较,CD3,+,、CD4,+,、CD4,+,/ CD8,+,水平差异有统计学意义,治疗组改善程度明显优于对照组(P,<,0.05)。结论：针灸联合耳穴疗法配合三阶梯常规止痛药治疗癌性疼痛,可明显减轻癌性疼痛,提高患者的生存质量与细胞免疫功能,还可一定程度减少止痛药的使用及止痛药所致的副反应。

Abstract

Objective:To observe the clinical efficacy of acupuncture combined with auricular therapy and three-step analgesic ladder in the treatment of cancer pain. Methods120 patients with cancer pain were randomly divided into the treatment group and control group,60 cases in each group. Both groups were treated with the basic therapy of three-step analgesic ladder. Additionally,the treatment group was treated with acupuncture combined with auricular therapy,and the control group was treated with sham acupuncture and auricular therapy,with a course of 21 days. The usage and side reactions of analgesics in three-step ladder were observed,and the visual analogue scale(VAS)score,Zubrod performance status(ZPS)score and the levels of natural killer(NK)cells and T cells(CD3,+,CD4,+,CD8,+,CD4,+,/CD8,+,)were compared. Results:①Finally 114 patients completed the whole trial,58 cases in the treatment group and 56 cases in the control group. ②After treatment,there was statistically significant difference on VAS score between the two groups,and the VAS score of the treatment group was obviously lower than that of the control group(P,<,0.05). ③At the end of the treatment,58.62% patients in the treatment group effectively reduced the analgesic usage or used the analgesics in lower ladder,while 17.86% patients in the control group did. There was statistically significant difference on the effective rate of drug reduction between the two groups(P,<,0.05). ④At the end of the treatment,the decrease on side reactions of analgesics was observed in 34.48% patients in the treatment group and 21.43% patients in the control group. There was statistically significant difference on the effective rate of side effects reduction between the two groups,and the effective rate of the treatment group was obviously higher than that of the control group(P,<,0.05). ⑤After treatment,there was statistically significant difference on ZPS score between the two groups,and the ZPS score of the treatment group was obviously lower than that of the control group(P,<,0.05). ⑥After treatment,there were statistically significant differences on the levels of CD3,+,CD4,+, and CD4,+,/ CD8,+, between the two groups,and the improvement in the treatment group was significantly better than that in the control group(P,<,0.05). Conclusion:Acupuncture combined with auricular therapy and three-step analgesic ladder can be used in the treatment of cancer pain,which can significantly alleviate the cancer pain and improve the quality of life and cellular immune function of patients. It also can reduce the analgesics usage and side reactions caused by analgesics to some extent.

关键词

癌性疼痛针刺镇痛耳穴疗法止痛药副反应生存质量免疫功能

Keywords

cancer painacupuncture analgesiaauricular therapyanalgesicsside reactionsquality of lifeimmune function

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