Review on bear bile and its potential alternative resources

ZHANG Xue-yan; WANG Tian-ming; WU Jia-sheng; MA Yue-ming

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Review on bear bile and its potential alternative resources

更新时间：2022-08-31

- Review on bear bile and its potential alternative resources
- Shanghai Journal of Traditional Chinese Medicine Vol. 51, Issue 9, Pages: 114-117(2017)
- 作者机构：
  
  1. 上海中医药大学中药学院,上海,201203
- 作者简介：
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ZHANG Xue-yan, WANG Tian-ming, WU Jia-sheng, et al. Review on bear bile and its potential alternative resources. [J]. Shanghai Journal of Traditional Chinese Medicine 51(9):114-117(2017)
DOI：

ZHANG Xue-yan, WANG Tian-ming, WU Jia-sheng, et al. Review on bear bile and its potential alternative resources. [J]. Shanghai Journal of Traditional Chinese Medicine 51(9):114-117(2017) DOI：

摘要

对比分析天然熊胆与熊胆的人工制品以及其他动物胆汁在化学成分、药理作用、临床应用等方面的异同。研究发现,人工合成熊胆在结合型胆汁酸牛磺熊去氧胆酸(TUDCA)、牛磺鹅去氧胆酸(TCDCA)的含量以及利胆、镇静、抗菌等药理作用方面在一定程度上已经达到天然熊胆的水平,可为寻找天然熊胆的替代资源提供参考。

Abstract

This article analyzed and compared the similarities and differences on chemical components,pharmacological effects and clinical application between natural bear bile and its artificial products or other animal bile. Research found that the contents of conjugated bile acids including tauroursodesoxycholic acid(TUDCA)and taurochenodeoxycholic acid(TCDCA)in artificially synthesized bear bile and its cholagogic,sedative and antibacterial effects were approximate to those of natural bear bile to some extent,which provided reference for searching alternative resources of natural bear bile.

关键词

熊胆胆汁酸化学成分药理作用临床应用替代

Keywords

bear bilebile acidchemical componentspharmacological effectsclinical applicationalternative resource

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