Clinical efficacy and mechanism research of Zexie Decoction in the treatment of essential hypertension

WANG Rui-xue; LIU Yan; ZHANG Shu-feng

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Clinical efficacy and mechanism research of Zexie Decoction in the treatment of essential hypertension

更新时间：2022-08-31

- Clinical efficacy and mechanism research of Zexie Decoction in the treatment of essential hypertension
- Shanghai Journal of Traditional Chinese Medicine Vol. 51, Issue 8, Pages: 103-105(2017)
- 作者机构：
  
  1. 承德医学院研究生学院,河北,承德,067000
- 作者简介：
- 基金信息：
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WANG Rui-xue, LIU Yan, ZHANG Shu-feng. Clinical efficacy and mechanism research of Zexie Decoction in the treatment of essential hypertension. [J]. Shanghai Journal of Traditional Chinese Medicine 51(8):103-105(2017)
DOI：

WANG Rui-xue, LIU Yan, ZHANG Shu-feng. Clinical efficacy and mechanism research of Zexie Decoction in the treatment of essential hypertension. [J]. Shanghai Journal of Traditional Chinese Medicine 51(8):103-105(2017) DOI：

摘要

综述泽泻汤治疗原发性高血压的临床疗效及其机制研究。泽泻复方治疗原发性高血压疗效确切,其降压机制主要通过调节肾素血管紧张素醛固酮系统(RAAS系统)、保护血管内皮、抑制血管重构、调控K,+,-Na,+,泵、保钾利尿、减轻胰岛素抵抗等环节,起到多机制、多环节、安全稳定的降压效果。

Abstract

This paper reviewed the clinical efficacy and mechanism research of Zexie Decoction in the treatment of essential hypertension. Zexie Decoction shows definite clinical efficacy in the treatment of essential hypertension. Its mechanism of anti-hypertension is mainly associated with the regulation of renin-angiotensin-aldosterone system(RAAS),protection of vascular endothelium,inhibition of vascular remodeling,regulation of K,+, and Na,+, pumps,potassium sparing diuresis,improvement of insulin resistance,which plays the safe and stable role of anti-hypertension with multi mechanism and targets.

关键词

泽泻汤临床疗效机制研究综述

Keywords

Zexie Decoctionclinical efficacymechanism researchreview

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