Clinical study of Compound Zijing Xiaoshang Cataplasm combined with glucosamine sulfate capsules in the treatment of early knee osteoarthritis

LI Zhi; ZHAI Wei-tao; MA Ying-hui

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Clinical study of Compound Zijing Xiaoshang Cataplasm combined with glucosamine sulfate capsules in the treatment of early knee osteoarthritis

更新时间：2022-08-31

- Clinical study of Compound Zijing Xiaoshang Cataplasm combined with glucosamine sulfate capsules in the treatment of early knee osteoarthritis
- Shanghai Journal of Traditional Chinese Medicine Vol. 51, Issue 5, Pages: 58-60(2017)
- 作者机构：
  
  1. 上海中医药大学研究生院,上海,201203
  2. 上海市光华中西医结合医院,上海,200052
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LI Zhi, ZHAI Wei-tao, MA Ying-hui. Clinical study of Compound Zijing Xiaoshang Cataplasm combined with glucosamine sulfate capsules in the treatment of early knee osteoarthritis. [J]. Shanghai Journal of Traditional Chinese Medicine 51(5):58-60(2017)
DOI：

LI Zhi, ZHAI Wei-tao, MA Ying-hui. Clinical study of Compound Zijing Xiaoshang Cataplasm combined with glucosamine sulfate capsules in the treatment of early knee osteoarthritis. [J]. Shanghai Journal of Traditional Chinese Medicine 51(5):58-60(2017) DOI：

摘要

目的：观察复方紫荆消伤巴布膏结合硫酸氨基葡萄糖胶囊治疗膝骨关节炎(KOA)的临床疗效。方法：将109例早期KOA患者随机分为观察组(55例)和对照组(54例),分别给予复方紫荆消伤巴布膏外用和硫酸氨基葡萄糖胶囊口服(观察组),疗程4周。观察两组临床疗效及治疗前后Lysholm膝关节功能评分、JOA膝关节功能评分、视觉模拟评分(VAS)。结果：①观察组临床总有效率为94.55%,对照组为81.48%；观察组临床总体疗效优于对照组(P<0.05)。②治疗后,观察组Lysholm评分和JOA评分均高于治疗前(P<0.05),VAS评分低于治疗前(P<0.05)；且观察组Lysholm评分和JOA评分高于对照组(P<0.05),VAS评分低于对照组(P<0.05)。结论：复方紫荆消伤巴布膏有助于改善KOA患者临床症状和膝关节功能。

Abstract

Objective:To observe the clinical efficacy of Compound ZijingXiaoshang Cataplasm combined with glucosamine sulfate capsules in the treatment of knee osteoarthritis(KOA). Methods109 patients with early KOA were randomly divided into the observation group (55 cases) and control group (54 cases). The control group was orally treated with glucosamine sulfate capsules,and the observation group was treated with Compound ZijingXiaoshang Cataplasm for external application based on the treatment for the control group,with a course of 4 weeks. The clinical efficacy was observed,and the Lysholm knee jointfunction score,Japan Orthopaedic Association (JOA) score and visual analogue scale (VAS) score in both groups were compared before and after treatment. Results:①The clinical total effective rate was 94.55% in the observation group and 81.48% in the control group. The overall clinical efficacy in the observation group was better than that in the control group(P<0.05). ②After treatment,the Lysholm score and JOA score in the observation group were increased compared with treatment before(P<0.05),the VAS score was decreased compared with treatment before(P<0.05). The Lysholm score and JOA score in the observation group were higher than those in the control group(P<0.05),and the VAS score in the observation group was lower than that in the control group(P<0.05). Conclusion:CompoundZijingXiaoshang Cataplasm can help to relieve the clinical symptoms and improve the knee joint function of patients with KOA.

关键词

膝骨关节炎复方紫荆消伤巴布膏关节功能

Keywords

knee osteoarthritisCompound ZijingXiaoshang Cataplasmjointfunction

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