Objective:To observe the clinical efficacy of Hongteng Mixture combined with Huayu Sanjie Enema in the treatment of chronic pelvic inflammatory disease(CPID)with syndrome of stagnant dampness-heat. Methods61 patients of CPID with syndrome of stagnant dampness-heat were randomly divided into the treatment group(31 cases)and control(30 cases).The control group was treated with Hongteng Mixture,and the treatment group as treated with Hongteng Mixture combined with Huayu Sanjie Enema,with a course of 3 months. The clinical efficacy was observed,and the TCM syndrome score,gynecological examination score,effusion volume in pelvic cavity under B-mode ultrasonography and hemorrheological parameters were compared.  Results:①The clinical total effective rate was 90.32% in the treatment group and 76.67% in the control group. The clinical efficacy of the treatment group was significantly better than that of the control group(P<0.05). ②For the comparison between groups after treatment,the decrease of TCM syndrome score and gynecological examination score in the treatment group were more significant than those in the control group(P<0.05). ③For the comparison between groups after treatment,the decrease of effusion volume in pelvic cavity in the treatment group was more significant than that in the control group(P<0.05). ④For the comparison between groups after treatment,the decrease of all hemorrheological parameters in the treatment group were more significant than those in the control group(P<0.05).  Conclusion:Hongteng Mixture combined with Huayu Sanjie Enema shows good efficacy in the treatment of chronic pelvic inflammatory disease with syndrome of stagnant dampness-heat.