Effects of Kechuan Liuwei Mixture on the lung function and life quality of severe COPD patients with syndrome of deficiency of kidney yang

MU Ying; WANG Wei; NI Wei

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Effects of Kechuan Liuwei Mixture on the lung function and life quality of severe COPD patients with syndrome of deficiency of kidney yang

更新时间：2022-08-31

- Effects of Kechuan Liuwei Mixture on the lung function and life quality of severe COPD patients with syndrome of deficiency of kidney yang
- Shanghai Journal of Traditional Chinese Medicine Vol. 51, Issue 2, Pages: 37-39(2017)
- 作者机构：
  
  1. 上海中医药大学附属龙华医院浦东分院,上海,200126
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MU Ying, WANG Wei, NI Wei. Effects of Kechuan Liuwei Mixture on the lung function and life quality of severe COPD patients with syndrome of deficiency of kidney yang. [J]. Shanghai Journal of Traditional Chinese Medicine 51(2):37-39(2017)
DOI：

MU Ying, WANG Wei, NI Wei. Effects of Kechuan Liuwei Mixture on the lung function and life quality of severe COPD patients with syndrome of deficiency of kidney yang. [J]. Shanghai Journal of Traditional Chinese Medicine 51(2):37-39(2017) DOI：

摘要

目的：评价咳喘六味合剂对重度COPD肾阳虚证患者肺功能和生活质量的影响。方法：将108例重度COPD稳定期患者随机分为对照组(36例)和治疗组(72例)；对照组给予舒利迭常规剂量吸入,治疗组给予咳喘六味合剂联合小剂量舒利迭吸入,疗程均为3个月。观察两组临床疗效及治疗前后患者肺功能、6 min步行距离、圣乔治呼吸问卷评分和生活质量评分的变化。结果：治疗组总有效率为84.72%,对照组为58.33%；治疗组临床疗效优于对照组(P,<,0.01)。治疗后,两组FEV,1,%较治疗前增加(P,<,0.05),但组间比较差异无统计学意义(P,>,0.05)。治疗后,两组患者6 min步行距离、圣乔治呼吸问卷和生活质量评分较治疗前增加(P,<,0.01),且治疗组增加较对照组显著(P,<,0.05)。结论：咳喘六味合剂可提高COPD临床疗效和改善患者肺功能及生活质量。

Abstract

Objective:To evaluate the effects of Kechuan Liuwei Mixture on the lung function and life quality of severe COPD patients with syndrome of deficiency of kidney yang. Methods 108 patients with severe COPD in stabilization period were randomly divided into the control group(36 cases)and the treatment group(72 cases). The control group was treated with Seretide inhalation at conventional dose,the treatment group was treated with Kechuan Liuwei Mixture combined with Seretide inhalation at small dose,with a course of 3 months. The clinical efficacy was observed,and the changes of lung function,6min walking distance,St. George’s respiratory questionnaire score and life quality score were compared before and after treatment. Results:The total effective rate was 84.72% in the treatment group and 58.33% in the control group,the clinical efficacy of the treatment was better than that of the control group(P,<,0.01). After treatment,the FEV,1,% in both groups was increased compared with the treatment before(P,<,0.05),but there was no statistically significant difference between the two groups(P,>,0.05). After treatment,the 6min walking distance and the scores of St. George’s respiratory questionnaire and life quality were increased in both group compared with the treatment before(P,<,0.01),and the increase in the treatment group were more significant than those in the control group(P,<,0.05). Conclusion: Kechuan Liuwei Mixture can enhance the clinical efficacy of COPD and improve the lung function and life quality of patients.

关键词

咳喘六味合剂慢性阻塞性肺疾病肺功能生活质量

Keywords

Kechuan Liuwei Mixturechronic obstructive pulmonary diseasepulmonary functionlife quality

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