Clinical research of the effects of Xi’s cortex erythrinae Decoction with external wash in the treatment of varicose ulcer of lower extremity

YAN Shao-qing; WANG Li-xiang; YANG Xiao; ZHANG Lei; LIU Guo-bin; XI Jiu-yi

您当前的位置：

首页 >

文章列表页 >

Clinical research of the effects of Xi’s cortex erythrinae Decoction with external wash in the treatment of varicose ulcer of lower extremity

更新时间：2022-08-31

- Clinical research of the effects of Xi’s cortex erythrinae Decoction with external wash in the treatment of varicose ulcer of lower extremity
- Shanghai Journal of Traditional Chinese Medicine Vol. 51, Issue 2, Pages: 54-57(2017)
- 作者机构：
  
  1. 上海中医药大学附属曙光医院周围血管科,上海,201203
  2. 上海市中西医结合医院脉管病科,上海,200086
- 作者简介：
- 基金信息：
- DOI：
  CLC：
扫描看全文
YAN Shao-qing, WANG Li-xiang, YANG Xiao, et al. Clinical research of the effects of Xi’s cortex erythrinae Decoction with external wash in the treatment of varicose ulcer of lower extremity. [J]. Shanghai Journal of Traditional Chinese Medicine 51(2):54-57(2017)
DOI：

YAN Shao-qing, WANG Li-xiang, YANG Xiao, et al. Clinical research of the effects of Xi’s cortex erythrinae Decoction with external wash in the treatment of varicose ulcer of lower extremity. [J]. Shanghai Journal of Traditional Chinese Medicine 51(2):54-57(2017) DOI：

摘要

目的：观察奚氏海桐皮汤外洗治疗下肢静脉曲张性溃疡(臁疮)的临床疗效。方法：将60例臁疮患者随机分为治疗组和对照组,每组30例。对照组予常规治疗,治疗组在对照组治疗措施基础上加予奚氏海桐皮汤外洗。两组疗程均为30天,观察临床疗效,比较临床症状及体征(溃疡大小、深浅、数量、色泽等方面)积分、炎症相关指标(WBC、hs-CRP)的变化情况。结果：①治疗组、对照组临床治愈率和总有效率分别为42.86%、95.24%和33.33%、88.89%；组间临床疗效比较,差异有统计学意义,治疗组显著优于对照组(P<0.05)。②组间治疗后比较,溃疡大小明显缩小,溃疡深浅和色泽明显好转,溃疡数量和渗液量明显减少,新生肉芽组织和新生上皮组织明显增多,疼痛程度明显缓解(P<0.05)。③治疗前后组内比较,两组WBC、hs-CRP水平差异有统计学意义,均显著降低(P<0.05)；组间治疗后比较,治疗组WBC、hs-CRP水平降低程度较对照组更甚(P<0.05)。结论：奚氏海桐皮汤外洗治疗下肢静脉曲张性溃疡(臁疮),能明显改善患者临床症状及体征,加快溃疡愈合速度。

Abstract

Objective:To observe the clinical efficacy of Xi’s cortex erythrinae Decoction with external wash in the treatment of varicose ulcer of lower extremity (ecthyma). Methods 60 patients with ecthyma were randomly divided into the treatment group and control group,30 cases in each group. The control group was received the conventional treatment,the treatment group was treated with Xi’s cortex erythrinae Decoction for external wash based on the treatment for the control group,with a course of 30 days. The clinical efficacy was observed,the scores of clinical symptoms and signs(the size,depth,quantity,color of ulcer and so on)and inflammation related indicators white blood cell(WBC),high sensitivity C-reactive protein(hs-CRP)were compared. Results: ①The clinical cure rate and total effective rate in the treatment group were 42.86% and 95.24% respectively,those in the control group were 33.33% and 88.89%. There were statistically significant differences on the clinical efficacy between the two groups,and the effect of the treatment group was significantly better than that of the control group(P<0.05). ②Compared with the control group after treatment, the size of ulcer was significantly reduced and the depth and color of ulcer was obviously improved in the treatment group, the quantity of ulcer and exudant were decreased obviously, and the neonatal granulation tissue and neonatal epithelial tissue were significantly increased, and the degree of pain was significantly relieved(P<0.05). ③For the comparison of treatment before and after within group,the levels of WBC and hs-CRP were significantly decreased in the two groups,with statistically significant differences(P<0.05). For the comparison between groups after treatment,the decrease of WBC and hs-CRP levels in the treatment were more significant than those in the control group(P<0.05). Conclusion: Xi’s cortex erythrinae Decoction with external wash can be used in the treatment of varicose ulcer of lower extremity (ecthyma),which significantly improve the clinical symptoms and signs of patients and accelerate ulcer healing.

关键词

臁疮下肢静脉曲张性溃疡奚氏海桐皮汤中药外洗炎症反应

Keywords

ecthymavaricose ulcer of lower extremityXi’s cortex erythrinae Decoctionexternal wash of Chinese materia medicainflammatory reaction

references

Views

338

下载量

CSCD

CNKI被引量

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of Xifeng Zhidong Decoction on inflammatory reaction of microglia induced by lipopolysaccharide in mice

Study on Yigong Powder promoting repair of spleen tissue structure by inhibiting inflammatory reactions in mice with anemia of chronic disease

Clinical observation of Tongyu Decoction in preventing cardiovascular events after castration of prostate cancer

Clinical study of Zizhu Ointment with external application in the treatment of venous ulcer in lower limb

Effects of Compound Fo’ercao Mixture on inflammatory factors in peripheral blood and expression of Toll like receptors in monocytes of AECOPD patients:A randomized, double-blind, placebo-controlled study

Related Author

No data

Related Institution

Deparment of Pediatrics， Shenzhen Traditional Chinese Medicine Hospital

Deparment of Traditional Chinese Medicine， Hangzhou Children’s Hospital

Deparment of Pediatrics， First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

Department of Hematology, Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine (Baoshan Branch of Shuguang Hospital, Shanghai University of Traditional Chinese Medicine)

Department of Traditional Chinese Medicine, Shanghai Fourth People’s Hospital Affiliated to Tongji University

⁰